Research works

EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy

Purpose EIF1, an RNA-binding protein implicated in multiple diseases, remains poorly characterized in diabetic retinopathy (DR). This study therefore investigated EIF1 expression and function in an in vitro model of DR pathogenesis. Methods Human retinal pigment epithelial cells...

Calcyon: An AI-Based Chatbot Framework for Calculus Learning to Support Computational Thinking Skill and Self-Regulated Learning

Abstract* Background The integration of artificial intelligence (AI) into mathematics education has advanced rapidly, yet limited attention has been given to systematic AI based chatbot frameworks that integrate computational thinking (CT) and self regulated learning (SRL) scaffo...

Turkish version of the Carolinas comfort scale: Validation and long-term clinical outcomes after mesh-based inguinal hernia repair

While generic instruments like the short form-36 (SF-36) and the visual analog scale (VAS) are staples in assessing quality of life and pain following hernia repair, they often struggle to capture the full clinical picture (6).The SF-36, being a broad health measure, frequently l...

Adolescent Experiences With Multiple Forms of Biased Victimization: A Typology of Bias Types in a Sample of Victims

As awareness of biased (or, identity-based) victimization and its harmful effects on student mental health has grown, it has become widely acknowledged that biased victimization is a serious problem worthy of specialized inquiry. However, past research has seldom examined youth e...

Persona-prompted LLM agents achieve modest but genuine prediction of human social media reactions

Abstract Social media platforms mediate how billions form opinions and engage with public discourse. As autonomous AI agents increasingly participate in these spaces, understanding their behavioral fidelity becomes critical for platform governance and democratic resilience. Previ...

Weil's Rosetta Stone as a correspondence of clocks, not of spaces

Weil's "trilingual text" — number fields, curves over finite fields, Riemann surfaces — is usually read as a dictionary between objects: primes ↔ points, Galois groups ↔ fundamental groups, and in Mazur's 3-dimensional refinement, primes ↔ knots, Legendre symbol ↔ linking number...

20-year experience of biomet stock alloplastic temporomandibular joint replacement in Chinese patients after technical modifications: a single-center retrospective study.

OBJECTIVES: To evaluate the clinical and radiographic outcomes of the Biomet stock alloplastic temporomandibular joint replacement (ATJR) after seven progressive surgical modifications in Chinese patients at a single center. MATERIALS AND METHODS: Patients who underwent ATJR from...

Early inflammatory response is associated with antibiotic treatment outcomes in acute phlegmonous appendicitis: a retrospective cohort study

Acute phlegmonous appendicitis is considered an intermediate inflammatory subtype between uncomplicated and complicated appendicitis. Although nonoperative management is increasingly accepted for uncomplicated appendicitis, evidence for phlegmonous appendicitis remains limited. T...

Inverse-Casimir Geometry of Nonunital Multipole Transport in Linear-Spin Lindbladians

## Overview This preprint studies the canonical Gorini--Kossakowski--Sudarshan--Lindblad (GKLS) class generated by jump operators linear in the generators of a fixed irreducible spin-$j$ representation. Writing the positive Kossakowski matrix as $C=R+iA$, with $R$ real symmetric...

Knowledge, Attitude and Perception of Dental Professionals and Students Toward Traditional and Complementary Medicine: A Cross‐Sectional Study

ABSTRACT Purpose/Objectives Traditional and Complementary Medicine (TCM) has gained global recognition, and Turkey officially regulates 15 TCM practices within its healthcare system. Despite increasing interest, the knowledge and attitudes of dental professionals and students rem...

Structure–Property Relationships of Tungsten Nitride Coatings on Copper Substrates Prepared by Reactive Direct Current Magnetron Sputtering

Tungsten nitride (WN) coatings were deposited on copper substrates by reactive direct current magnetron sputtering using deposition times of 15, 30, 45, and 60 min. The influence of deposition time on the structural, morphological, and electrical properties of the coatings was sy...

Prime Analysis: Expressing Primes As Triangles

Prime Numbers have been a hot topic around mathematics for centuries. Many theories have been devised such as the Riemann Hypothesis, Twin Prime Conjecture, etc. However, prime theories involve using many advanced concepts such as the imaginary number and contour integration maki...

Design of a High-Resolution Reconfigurable Intelligent Surface for Slowly Time-Varying Scenarios

Reconfigurable intelligent surfaces (RISs) are emerging as a key enabling technology to engineer the wireless propagation environment in 5G/6G systems. This paper presents the design, characterization, and control of a high-resolution RIS targeting slowly time-varying scenarios,...

PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes

Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high intraocular pressure (ph-IOP). Despite the established role of ferroptosis in RGC degeneration, specific molecular...

Reason For Using Frequency And Percentage To Analyse Categorical Data

Data analysis in social science and information management research depends heavily on matching statistical techniques with the correct level of variable measurement. Categorical data, comprising nominal and ordinal scales such as demographic profiles, information access levels,...

The Worldwide Burden of Parkinson's Disease Is Growing, but Its Incidence Is Not: Lessons from Population‐Based Studies

Data sharing not applicable to this article as no datasets were generated or analysed during the current study. Supporting Information. COI_disclosure. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the aut...

Ethylene and 1-methylcyclopropene modulate aroma volatile profiles in kiwifruit (Actinidia spp.) during postharvest storage

Abstract Kiwifruit is a climacteric fruit, and ethylene-mediated ripening accelerates quality deterioration during storage. In this study, volatile compound composition was profiled during storage for 0–10 d under control, ethylene, and 1-methylcyclopropene (1-MCP) treatments. A...

Scalable Fabrication of Highly Ordered Au/Ag Composite Nanoshell Array for Ultrasensitive SERS Detection of Trace Pesticides

Surface-enhanced Raman scattering is highly promising for trace molecular detection but requires substrates with both ultrahigh sensitivity and macroscopic uniformity. Current bimetallic nanostructures struggle to achieve large-area structural reproducibility and high-density “ho...

Glucagon-Like Peptide-1 Receptor Agonists for Obstructive Sleep Apnea

Importance Obstructive sleep apnea (OSA) affects nearly 1 billion adults worldwide and is independently associated with cardiovascular disease, stroke, and increased mortality. While continuous positive airway pressure (CPAP) remains the criterion standard treatment, adherence ra...

Neurocognitive outcomes in pediatric brain arteriovenous malformations: a systematic review

Introduction Pediatric brain arteriovenous malformations (AVMs) are an important cause of hemorrhagic stroke and long-term morbidity. Neurocognitive outcomes remain incompletely characterized. Objective To synthesize reported neurocognitive, educational, and occupational outcomes...