Research works

Unlocking the impact of ICALL across proficiency levels: EFL learners’ language achievement and multidimensional engagement

This quantitative quasi-experimental study examined whether Intelligent Computer-Assisted Language Learning (ICALL)-based instruction improved Chinese English as a Foreign Language (EFL) learners’ language achievement and multidimensional engagement across elementary, intermediat...

Local control of RCC pancreatic metastases is obtained by angiogenesis inhibitors

Background Metastatic clear-cell renal cell carcinoma (m-ccRCC) with pancreatic and/or thyroid metastases (PM/TM) is sensitive to vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs). Optimal first-line therapy for these patients (VEGFR-TKI-monother...

Myrsine fossil pollen from the Oligocene of Iberia provides evidence for early Eurasian dispersal

The Cenozoic fossil record of Myrsine (Primulaceae) in Europe is largely based on leaf macroremains of uncertain taxonomical attribution and consequently remains poorly understood. In this study, we report the first well-documented European fossil pollen record attributable to ea...

Human-Anchored Compute Governance: A Proposal for Physical, Time-Limited Human Authorization of High-Risk AI Compute

Human-Anchored Compute Governance (HACG) is a technical proposal for an independently enforced, time-limited human authorization layer over a defined boundary of high-risk AI compute. The reference architecture combines local human quorum authorization, offline credentials, an in...

Design and Optimization of Smart-Grid-Connected Microgrids for EV Charging Stations Integrating Net Energy Metering and Demand Response

The widespread adoption of EVs is expected to intensify peak demand, stress distribution networks, and increase carbon emissions if traditional grid-based charging models continue. Therefore, this study proposes a smart-grid-connected microgrid (MG) architecture for EV charging s...

Dual primary malignancies are no longer a rarity: A single centre experience from eastern India

Objectives: Advancements in cancer therapies have improved long-term survival rates, contributing to an increased incidence of second primary malignancies. This study aims to describe the clinical characteristics, tumour profiles, and treatment patterns of patients diagnosed with...

E8 Phased-Locked Consciousness Resonance at 132Hz — E8 Intelligence Research

The 240 E8 root vectors, scaled by φ from a 132Hz base, establish a nested phase-locking hierarchy that correlates with gamma-wave synchronization in EEG, suggesting a geometric underpinning for conscious perception and quantum coherence in neural networks. Division: Biology & Co...

FORMULATION AND EVALUATION OF HERBAL SUNSCREEN CREAM CONTAINING GUAVA LEAF EXTRACT

Prolonged exposure to ultraviolet (UV) radiation is a major cause of photoageing, sunburn, and skin cancer, creating sustained demand for effective and safe sunscreen formulations. Synthetic UV filters, though effective, are increasingly associated with dermal and environmental c...

Colon cancer in a patient with a mosaic monoallelic germline pathogenic NF1 gene variant

Pathogenic variants in the tumor suppressor gene NF1 cause neurofibromatosis type 1 (NF1), one of the most common hereditary cancer predisposition syndromes. Pathogenic NF1 variants have been associated with an increased risk of several cancers; however, the relationship between...

Global connection, local exception: the gateway politics of infrastructure in an Italian port city

In the context of a global push for infrastructure, states pursue spatial strategies to secure centrality in global networks and control logistical flows. Contemporary scholarship on the infrastructure state calls for examining the reorganization of urban environments that sustai...

Screening ‘Gum Disease or Problem’ Status Using Molar Probing Depths: Model Development and Validation in NHANES Young to Middle-Aged Adults

Background/Objectives: A parsimonious multivariable model was engineered and externally validated using dental electronic health records to screen for a clinician-evaluated “gum disease or related problem” status. Designed for seamless electronic integration, a positive screening...

Feasibility and effects of a multicomponent program incorporating esports on physical and cognitive function among older adults: A non-randomised pilot trial

Background Esports (competitive and organised video gaming) may enhance physical and cognitive health in older adults. The aim of this study was to examine the feasibility and effects of a multicomponent program incorporating esports on physical and cognitive function in communit...

IFC-HFlowVAE: A self-enhancing generative framework with structural anchoring for imbalanced clinical data augmentation

Class imbalance and limited minority-class samples remain major challenges for developing reliable clinical diagnostic models, as insufficient observations often fail to capture complex minority-class distributions. Existing augmentation methods either rely on heuristic interpola...

E8 Phi-Phased Dispersionless Waveguide — E8 Intelligence Research

The 240 E8 root vectors can be paired into 120 orthogonal phi‑scaled directions that, when driven at the 132 Hz base frequency, generate a standing wave whose phase increments equal the golden ratio (≈1.618). This phi‑phased standing wave aligns with consecutive lattice points, p...

E8 Root Vector Phase-Locking in Spin-½ Nuclear Magnetic Resonance — E8 Intelligence Research

The 240 root vectors of the E8 lattice serve as the discrete optimal configuration states for spin-½ nuclei, where Phosphorus-31 precession undergoes quantized jumps between adjacent root-vector orientations. This phenomenon creates a geometric phase-locking effect, where the 132...

Tendon morphological and mechanical responses to eccentric and heavy-slow resistance training in Achilles and patellar tendinopathy: a scoping review

Tendinopathy is a disabling and painful condition commonly associated with repetitive mechanical loading. Eccentric training (ECC) has been widely used in rehabilitation but can be mechanically demanding and pain-provoking. Heavy-Slow Resistance Training (HSRT) has emerged as an...

Smartphone based clinical decision support system for early detection of neonatal jaundice using artificial intelligence with temporal convolutional network

Abstract Physiological jaundice is present in the initial week of life in neonates owing to the rise in level of bilirubin thereby resulting in yellowish coloring of sclera and skin. Severe jaundice and lethal bilirubin levels may result from brain damage as bilirubin is located...

The Risk Spillover Within a Financial System: Evidence from China

In this paper, by proposing a new risk measure called CoRVaR, we explore the risk spillover effect within a financial system consisting of the banking, security and insurance industries. To be precise, we examine the risk spillover effect from each industry to the other. Moreover...

Management of job stress among higher education academics: a randomised controlled trial evaluation of rational emotive behaviour therapy

Researchers’ observations as academics in higher institutions have shown that the university environment in the Nigerian context has a lot of stressors and such have the potential of impeding the work effectiveness of university staff. In the ideal situation, academics’ target is...

Maternal DNA repair safeguards genome stability during the oocyte-to-embryo transition

Abstract De novo mutations are a major source of genetic variation and disease risk, yet the developmental timing and mechanisms underlying their origin require further investigation. While germ cells have traditionally been considered the primary source of these mutations, incre...