Research works

Longitudinal dynamics of gene expression and metabolomics in an aging population cohort

Multiomic profiling provides a comprehensive physiological overview at the molecular level, but understanding of its spatiotemporal dynamics remains limited in human populations. We profiled longitudinal whole-blood gene expression and metabolite levels in 335 females over 8 year...

THE PELASGIANS AND THE LELEGES.- PELASGI & LELEGES. WHO WHERE THEY? In Ancient Egyptian, Greek, Hebrew, and Latin Sources – A Comprehensive Collection

Preface The Pelasgians and the Leleges are the two principal pre-Greek peoples of ancient tradition. According to ancient literary sources, they inhabited the regions surrounding the Aegean Sea, including its islands, mainland Greece—particularly Arcadia, traditionally regarded a...

HOW TO PRODUCE ORIGINAL SCIENTIFIC ARTICLES AT THE CUTTING EDGE OF KNOWLEDGE USING THE ALGUILAS METHOD? THE ALGUILAS PROMPT PACK READY TO RUN.

How to use this pack (Beta Version) Option 1: Upload this file to an AI agent – preferably as part of a new project within the agent – and request that the Alguilas Method be run. The rest will proceed as normal. In other IAs: After generating a Word file containing the paper, us...

Very-long chain fatty acids increase cell membrane thickness and impair mitochondrial function of aortic smooth muscle cells: implications for early vascular ageing

Aleksandra Hliwa-Ślazyk, Magdalena Narajczyk, Magdalena Dzitkowska-Zabielska, Marika Franczak, Tomasz Sledzinski, Krzysztof Narkiewicz, Adriana Mika; Very-

Biomechanical Contributions to Alterations in Peak Metabolic Capacity and Efficiency Following Locomotor Training in Individuals After Stroke

Abstract Importance Changes in peak metabolic capacity (Vo2peak) and gait efficiency at matched speeds (Vo2match) are often observed in individuals after stroke following locomotor training, although it is uncertain how those changes are achieved. Objective The objective of this...

A Comprehensive Evaluation of Food and Agricultural Policies in California General Plans

Problem, research strategy and findings Agriculture and urban interests often compete fiercely for land and water, particularly in California. In this study we offer the first state-level assessment of planning for agriculture and food systems, with a focus on identifying competi...

A Skeleton-Line-Based Spiral Coverage Path Planning Method for UAV Inspection of Three-Dimensional Structures

UAV-based visual inspection has become an effective approach for acquiring surface information from three-dimensional building structures. However, existing coverage path planning methods usually treat viewpoint planning and path sequencing as two separate stages, which may intro...

Pleura organoid transplantation facilitates visceral pleural repair through CD133+ progenitor cell-mediated regeneration

Abstract Persistent pulmonary air leakage following thoracic surgery remains a major clinical challenge. Here we establish murine and human pleura organoids as a novel regenerative therapy. Morphological and functional analyses confirm that these organoids retain mesothelial mark...

False-positive patterns in optical coherence tomography in hyperopic and myopic eyes

Background/aims This study aimed to evaluate how axial length influences false-positive rates in ganglion cell analysis (GCA) and retinal nerve fibre layer (RNFL) maps and to identify distinct false-positive patterns on optical coherence tomography (OCT) deviation maps across axi...

Noise-Enhanced Hamming Code Transmission over an Additive Gaussian Mixture Noise Channel with One-Bit ADCs

Random noise may have a positive effect on the transmission and reception of signals in some nonlinear communication systems, which is termed as stochastic resonance (SR) or noise-enhanced effect. In this paper, we investigate the performance of signals transmitted over an additi...

Muhannad Heating Theory ( MHT )

Muhannad Heating Theory is theoretical concept explain electromagnetic waves and mechanical waves union mechanism when specific frequencies and wavelengths and effect of mechanism on specific polar materials for super-heating.

Reference-standard and calibration-model dependence of AlCl3-reactive flavonoid estimates in yemeni Malva verticillata L. leaf extract

Aluminum chloride colorimetry is widely used for preliminary flavonoid estimation, but results depend on reference standard, calibration model, and unresolved sample optical background. We re-analysed archived data from a completed undergraduate thesis on a methanolic leaf extrac...

Engineered Hierarchical Porosity in Three-Dimensional-Printed Hydrogel Scaffolds Enhances Mesenchymal Stem Cell Therapy for Chronic Diabetic Wounds

Abstract Unhealing chronic diabetic wounds is a major clinical challenge, as it is rooted in the complex pathological microenvironment, including neuropathy, angiopathy, and chronic inflammation. Traditional treatment methods cannot fundamentally solve these problems. Inspired by...

Theodorus Spiral as E8 Harmonic Growth Envelope at the Golden Angle — E8 Intelligence Research

When the 240 E8 root vectors are projected through successive golden-angle rotations (137.51°) at the 132Hz base frequency, their radial endpoints trace a discrete lattice that converges precisely onto the Theodorus root-spiral envelope — revealing that the Theodorus spiral is no...

A peroxidase-mimetic platinum nanocluster induces concurrent DNA damage and oxidative cleavage in paediatric glioblastoma cells

The impermeability of the blood–brain barrier (BBB), formed by a monolayer of endothelial cells, remains a major obstacle for delivering chemotherapeutic drugs to the brain. Ultra-small nanoparticles, particularly nanoclusters smaller than 2 nm, offer a promising strategy to over...

Intermediate risk thyroid cancer management: physician survey

Abstract Context Variability exists in use of radioactive iodine (RAI) treatment in intermediate risk (IR) thyroid cancer. Objective The study surveyed clinicians about their use of RAI in theoretical cases of patients with IR thyroid cancer. Design A survey presented patient cas...

E8 Root Lattice Synchronization for Fault‑Tolerant Quantum Metrology — E8 Intelligence Research

By mapping the Hilbert series poles of the E8 invariant ring onto a set of 240 synchronized 132 Hz phononic modes, we construct a multi‑frame entangled resource that simultaneously encodes a topological error‑correcting code and a metrological phase reference. The φ‑coupled 8‑fra...

Integrating molecular engineering and artificial intelligence to overcome clinical and manufacturing challenges in CAR-T therapy

Chimeric antigen receptor (CAR) T-cell therapy has demonstrated remarkable efficacy in addressing hematological malignancies. However, its broader clinical application in other cancer types is still limited by key challenges like antigen escape, on-target/off-tumor toxicity, redu...

Histological placental abnormalities and associated factors among malaria smear-positive women delivering at two tertiary hospitals in Uganda: a comprehensive multicenter cross-sectional study

Malaria in pregnancy may disrupt placental structure and function, but evidence describing placental abnormalities among malaria-positive women in Uganda remains limited. This study determined the prevalence and patterns of gross and histological placental abnormalities and exami...

RDIC-MSCKF: Risk–Direction-Decoupled and Innovation-Calibrated MSCKF for Stereo Visual-Inertial Odometry

Filtering-based stereo visual-inertial odometry often assigns fixed or uniformly scaled covariance to tracks accepted by the front-end, although accepted observations can differ in terms of tracking reliability, local directional identifiability, and agreement with the batch-leve...