Research works

COMPARATIVE EVALUATION OF SEALING ABILITY OF THREE INJECTABLE BIOCERAMIC PUTTIES IN PERFORATION REPAIR USING DYE PENETRATION METHOD

Background: Injectable bioceramic putty provide effective sealing in perforation repair. Materials with superior marginal adaptation and bioactivity may improve long-term prognosis and reduce endodontic failure due to microleakage. Aim: The present in vitro study aimed to evaluat...

PENTALINON LUTEUM A DETAILED PHARMACOLOGICAL APPROACH

The data were collected from Current Contents and Scientific Journals, which included in publications. Pentalinon luteum have anti-inflammatory activity along with their phytochemical constituents and also mention the family, leaf of platinon leutium play a significant role in hu...

POLYMER STABILIZED BARIUM TUNGSTATE (BAWO4) NANOPARTICLES FOR ENHANCED PLANT GROWTH AND ANTIFUNGAL ACTIVITY

This study investigates the potential of polymer-encapsulated barium tungstate (BaWO4) nanoparticles (NPs) as an agent for promoting plant growth and suppressing fungal pathogens. BaWO4 nanoparticles were synthesized via a chemical route and coated with polyvinyl pyrrolidone (PVP...

A CASE STUDY – EFFECT OF KUSHTHADI CHURNA IN THE MANAGEMENT OF PRAMEHA (DIABETES MELLITUS TYPE II)

Diabetes is a major health problem affecting mankind since ancient times. Both developed and developing countries are witnessing a rapid rise in glycaemic level among the population. Diabetes is a metabolic disorder characterized by impaired carbohydrate utilization and enhanced...

INTRANASAL GEL TO TREAT PARKINSON DISEASE

Parkinson disease the second most common neurodegenerative disease caused due to the degeneration of dopaminergic neuron in substantial nigra results in the depletion of striatum dopamine.[1] The symptoms of this disease are classified into motor and non-motor symptoms. The motor...

EFFECT OF INDRAYAVADI YOGA IN THE MANAGEMENT OF SHWETA PRADARA – A CASE SERIES

Background: Shweta Pradara is described in Ayurveda as excessive, white vaginal discharge caused predominantly by vitiation of Kapha Dosha along with involvement of Rasa Dhatu and Artavavaha Srotas. It can be clinically correlated with leucorrhoea in modern gynecology. Improper d...

COMPREHENSIVE ANALYSIS OF THE ANTI-INFLAMMATORY POTENTIAL OF KSHARAGAD EXTRACTS: AN INVITRO STUDY

Inflammation is a protective response of the body against harmful stimuli such as infection, injury, toxins, and immune reactions. In Ayurveda, inflammatory conditions are broadly described under the concept of Shotha, which is caused by the imbalance of Doshas and other external...

AYURVEDIC INTERVENTION IN COMBATING CHEMO-RADIOTHERAPY-INDUCED OTOTOXICITY: A TWO - CASE SHORT COMMUNICATION

Cancer treatment commonly includes surgery, chemotherapy, radiotherapy, or a combination of these modalities. While these approaches have substantially improved survival, many patients continue to experience late adverse effects that affect long-term quality of life. Ototoxicity...

IDENTIFYING RISK FACTORS ASSOCIATED WITH MUSCULOSKELETAL SYMPTOMS IN FREQUENT COMPUTER USERS IN PATHANAMTHITTA, KERALA: A COMMUNITY-BASED PROSPECTIVE STUDY

Background: Globally, musculoskeletal conditions has increased by 25 percent over the past decade and makes up 2% of the global disease burden. As the use of computer at school, work and for social media is growing, people are suffering from musculoskeletal symptoms and its disor...

UV VISIBLE SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF FINASTERIDE AND DUTASTERIDE

A simple, accurate, precise, and economical UV-visible spectrophotometric method was developed and validated for the simultaneous estimation of Finasteride and Dutasteride in bulk drug samples and pharmaceutical dosage forms. The method was developed according to International Co...

SCANNING ELECTRON MICROSCOPIC EVALUATION OF ROOT SURFACE ALTERATION INDUCED BY DIFFERENT ROOT BIOMODIFICATION AGENTS: AN IN-VITRO COMPARATIVE STUDY

Successful periodontal regeneration requires the establishment of a biologically compatible root surface that facilitates the attachment, migration, and proliferation of periodontal ligament cells and gingival fibroblasts. Mechanical instrumentation by scaling and root planing (S...

DIFFERENT FORMULATION AND EVALUTION OF CARICA PAPAYA LINN

Carica papaya Linn. is a medicinally important plant widely used in traditional systems of medicine due to its antioxidant, anti-inflammatory, antimicrobial, and wound-healing properties. The present study focuses on the formulation and evaluation of different dosage forms prepar...

UV SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION OF PREGABALIN

The objective of this study was to develop and validate a simple, sensitive, and economical UV-visible spectrophotometric method for the estimation of Pregabalin in bulk drug and pharmaceutical dosage forms. Pregabalin is commonly prescribed for the treatment of neuropathic pain,...

AN UNUSUAL PRESENTATION OF ICTERUS DURING SAMSARJANA KRAMA FOLLOWING VIRECHANA: A CASE REPORT

Background: Urticaria (Shitpitta) is an Ayurvedic disorder characterised by recurrent episodes of itching, erythema, and skin eruptions resulting from vitiation of Doshas, predominantly Pitta and Vata. Virechana Karma is considered the principal Panchakarma therapy for the manage...

LIPOSOMAL DRUG DELIVERY OF HERBAL EXTRACT

Nanoliposome-based delivery systems for drugs have been proposed as a promising strategy to improve the therapeutic efficacy of herbal extracts. Although herbal bioactive compounds have important pharmacological activities including antioxidant, anti-inflammatory, antimicrobial,...

EFFECT OF INDRAYAVADI YOGA IN THE MANAGEMENT OF SHWETA PRADARA – A CASE SERIES

Background: Shweta Pradara is described in Ayurveda as excessive, white vaginal discharge caused predominantly by vitiation of Kapha Dosha along with involvement of Rasa Dhatu and Artavavaha Srotas. It can be clinically correlated with leucorrhoea in modern gynecology. Improper d...

RARE MEDICINAL PLANT HUGONIA BELLI SEDGW. PHYTOCHEMICAL PROFILING AND IN VITRO ANTIMICROBIAL PROPERTIES OF THE METHANOLIC LEAF EXTRACT

Hugonia belli, popularly known as Modira kanni gida, is a rare plant species in India. The main objective of this study was to examine the phytochemical constituents and in vitro antimicrobial activity of this plant. Qualitative screening revealed the presence of phenols, alkaloi...

DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME SUBSTITUTED 1,3,4- THIADIAZOLE DERIVATIVES AS AN ANTI-INFLAMMATORY AGENT

Background: Inflammation is a fundamental pathological process implicated in numerous chronic diseases. Current anti-inflammatory therapies, are associated with significant adverse effects, prompting the search for safer and more effective agents. 1,3,4-Thiadiazoles, have demonst...

AN APPLIED STUDY OF NINE-CENTER MEDITATION FOR REDUCING MOBILE PHONE ADDICTION IN SCHOOL STUDENTS

This randomized experimental investigation examined the effects of a structured Nine-Center Meditation programme on mobile phone addiction among school students. The investigators hypothesized that consistent participation in Nine-Center Meditation would result in significant red...

A CRITICAL REVIEW OF INDRIYASTHANA OF CHARAKA SAMHITA: ARISHTA LAKSHANA AS PROGNOSTIC BIOMARKERS — A COMPARATIVE STUDY WITH PALLIATIVE MEDICINE AND TERMINAL ILLNESS INDICATORS

Ayurveda places primary emphasis on the prevention of disease and embraces a holistic philosophy in addressing diverse states of ill-health. Among the pillars of clinical practice, prognosis occupies a position of central importance, since a reliable estimate of the residual cour...