Research works

FORMULATION AND EVALUATION OF MANTELUKAST SODIUM CHEWABLE TABLET

Montelukast sodium is a selective leukotriene receptor antagonist widely used for the prophylaxis and chronic management of asthma and allergic rhinitis. The present study aimed to formulate and evaluate Montelukast sodium tablets with improved tablet performance, rapid drug rele...

FORMULATION AND CHARACTERIZATION OF HERBAL ANTI-AGING CREAM ENRICHED WITH CAMPHOR AND SEA BUCKTHORN OIL

Skin aging is a natural biological process influenced by intrinsic and extrinsic factors such as ultraviolet radiation, oxidative stress, environmental pollution, and lifestyle. These factors lead to collagen degradation, reduced skin elasticity, wrinkle formation, and dryness. H...

AN INTERESTING CASE OF ACUTE FLACCID PARALYSIS: A DIAGNOSTIC CHALLENGE

Acute Flaccid Paralysis (AFP) is a complex, neurological clinical syndrome characterized by the rapid onset of profound muscle weakness, hypotonia, and diminished or absent deep tendon reflexes. The progression of weakness can be aggressive, occasionally leading to devastating co...

YUKTI TO NANO-PHARMACOLOGY: UNDERSTANDING ALPAMATRA MAHARTHATVAM AND THE THERAPEUTIC POTENTIAL OF RASAUSHADHIS

Background: Rasaushadhis represent a unique class of herbo-mineral formulations in Ayurveda, distinguished by three remarkable characteristics: administration in minute doses (Alpamatra), rapid therapeutic action (Kṣipramarogyadayitvat), and patient palatability (Arucheraprasanga...

फलसव WSR To KAJAVASAVA IN KAPHAJA KASA PHALASAVA: WSR To KAJAVASAVA IN KAPHAJA KASA

Kaphaja Kasa is a common respiratory disorder described in Ayurveda, primarily caused by the vitiation of Kapha Dosha, leading to symptoms such as productive cough with thick, white or Pandu-coloured sputum, heaviness, and chest congestion. The management of Kaphaja Kasa focuses...

PRECISION THERAPEUTICS IN PRIMARY IMMUNE REGULATORY DISORDERS: CURRENT ADVANCES AND FUTURE DIRECTIONS

Primary immune regulatory disorders (PIRDs) are a heterogeneous group of inborn errors of immunity characterized by impairment of immune tolerance and homeostasis leading to autoimmune, autoinflammatory, lymphoproliferative diseases and recurrent infections. Recent developments i...

ASSOCIATION OF ANTIBIOTIC RESISTANCES AMONG MYCOBACTERIUM TUBERCULOSIS AMONG SALAH-ALDEEN COMMUNITY

Background: Mycobacterium tuberculosis, the etiological agent causing tuberculosis, is one of the most common contagious diseases that poses a serious threat to human health. As per the recent WHO report, TB incidence throughout the world amounts to 10.7 million and the total dea...

PREVALENCE OF TINEA AMONG PATIENTS ATTENDING DERMATOLOGY CONSULTATION UNITS IN MOSUL CITY

Dermatophyte infections (tinea) are common superficial fungal infections of the skin, hair, and nails that constitute a substantial public health burden, particularly in developing countries. This cross-sectional study aimed to determine the prevalence, demographic distribution,...

MANAGEMENT OF INDRALUPTA (DRUG INDUCED ALOPECIA)- A CASE STUDY

Introduction: Indralupta falls under one of the Urdhwajatrugata Vyadhi characterized by the patchy hair loss over hair-bearing skin that includes scalp and beard. According to the Acharya Sushruta, Indralupta is due to the vitiated pitta in association with vitiated Vata causing...

SUCCESSFUL PREGNANCY FOLLOWING INTEGRATIVE AYURVEDIC MANAGEMENT IN A WOMAN WITH UNILATERAL TUBAL BLOCKAGE, HYPERTHYROIDISM, POOR OVARIAN RESERVE, AND PREVIOUS ECTOPIC PREGNANCY: A CASE REPORT

Background: Tubal factor infertility accounts for approximately 25–35% of female infertility. Women with unilateral salpingectomy following ectopic pregnancy and contralateral tubal blockage have limited options for natural conception and are frequently advised assisted reproduct...

DEVELOPMENT AND EVALUATION OF FINASTERIDE NANO-SUSPENSIONBASED TOPICAL DELIVERY FOR ENHANCED THERAPEUTIC EFFICACY

Finasteride is an effective 5α-reductase inhibitor used in the management of androgen-dependent hair disorders; however, oral administration is associated with systemic adverse effects and limited patient compliance. The present study aimed to develop and evaluate a finasteride n...

SAMHITA PRINCIPLES IN THE MANAGEMENT OF DISEASES: AN AYURVEDIC REVIEW

Ayurveda, the traditional system of medicine of India, has made a significant contribution to healthcare since ancient times and continues to gain worldwide recognition. Among its fundamental concepts, Samhita Siddhanta forms the cornerstone of understanding the etiology, pathoge...

STABILITY-INDICATING HPTLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF GABAPENTIN AND NORTRIPTYLINE IN BULK DRUG AND MARKETED FORMULATION

Gabapentin and nortriptyline are co-formulated (100 mg/10 mg and 200 mg/10 mg strengths) and used for the management of neuropathic pain, yet no stability-indicating high-performance thin-layer chromatographic (HPTLC) method for their simultaneous estimation has been reported to...

ARTIFICIAL INTELLIGENCE IN HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY: TRANSFORMING METHOD DEVELOPMENT, OPTIMIZATION, AND DATA ANALYSIS- A COMPREHENSIVE REVIEW

High-Performance Liquid Chromatography (HPLC) is a critical analytical technique for separating, identifying, and quantifying compounds, but traditional gradient method development is resource-intensive and time-consuming. This review explores the integration of artificial intell...

IN VIVO EVALUATION OF THE ANTI-ALZHEIMER'S POTENTIAL OF THE ETHANOLIC EXTRACT OF ARTOCARPUS HETEROPHYLLUS SEEDS IN SCOPALAMINE- INDUCED MALE ALBINO RATS

Alzheimer's disease (AD) is a chronic, progressive neurodegenerative disorder and the leading cause of dementia worldwide. It is characterized by progressive deterioration of memory, cognition, language, executive function, and behavior, ultimately affecting activities of daily l...

IMPACT OF HEADPHONES AND IN-EARBUDS ON HEARING PERCEPTION AND KARNANADA (TINNITUS) AMONG YOUNG ADULTS: AN OBSERVATIONAL CROSS-SECTIONAL STUDY

Background: The widespread adoption of personal audio devices (PADs), particularly headphones and in-earbuds, has increased the risk of recreational noise-induced hearing loss (NIHL) and tinnitus among young adults. Ayurveda describes similar auditory manifestations under Karnana...

PREVALENCE OF TINEA AMONG PATIENTS ATTENDING DERMATOLOGY CONSULTATION UNITS IN MOSUL CITY

Dermatophyte infections (tinea) are common superficial fungal infections of the skin, hair, and nails that constitute a substantial public health burden, particularly in developing countries. This cross-sectional study aimed to determine the prevalence, demographic distribution,...

AN AYURVEDIC APPROACH IN THE MANAGEMENT OF VIPADIKA (PALMOPLANTAR PSORIASIS) - A CASE REPORT

Palmo-plantar psoriasis is a non-infectious chronic inflammatory dermatological condition that predominantly affects the palms and soles and is capable of producing significant functional disability. It is characterized by erythema, scaling, itching, fissuring, pustule formation,...

INDIVIDUALIZED AYURVEDIC MANAGEMENT RESULTING IN NATURAL CONCEPTION AFTER REPEATED FAILED ASSISTED REPRODUCTIVE TECHNOLOGY CYCLES: A CASE REPORT

Background: Infertility is a multifactorial condition that can significantly affect the emotional, psychological, and social well-being of couples. Repeated failures of assisted reproductive techniques such as intrauterine insemination (IUI) and in vitro fertilization (IVF) often...

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF IMEGLIMIN IN BULK AND PHARMACEUTICAL DOSAGE FORM

Imeglimin Hydrochloride is a novel anti-diabetic drug used in the management of Type 2 Diabetes Mellitus. The present study focuses on the development and validation of a simple, precise, accurate, and economical Reverse Phase High-Performance Liquid Chromatography (RP-HPLC) meth...