Research works

AN APPLIED STUDY OF NINE-CENTER MEDITATION FOR REDUCING MOBILE PHONE ADDICTION IN SCHOOL STUDENTS

This randomized experimental investigation examined the effects of a structured Nine-Center Meditation programme on mobile phone addiction among school students. The investigators hypothesized that consistent participation in Nine-Center Meditation would result in significant red...

DEVELOPMENT AND CHARACTERIZATION OF AMLODIPINE LOADED SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEM NEEDS FOR EFFECTIVE HYPERTENSION TREATMENT

Through the development of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS), the current project aims to improve the oral bioavailability and therapeutic efficacy of amlodipine, a weakly water soluble hypertension medication. Tween 20 was used as the surfactant and peppermint...

FORMULATION AND EVALUATION OF GLIPIZIDE MICROEMULSION

Glipizide is a second-generation sulfonylurea used in the treatment of Type 2 diabetes mellitus. Because of its poor aqueous solubility (BCS Class II), its oral bioavailability is limited by a slow dissolution rate. Microemulsion-based drug delivery systems are thermodynamically...

A REVIEW ON PHYTOPHARMACOLOGICAL SCREENING OF CASSIA FISTULA LINN. IN EXPERIMENTAL ANIMAL MODELS

Medicinal plants have been used for thousands of years as an important source of therapeutic agents for the prevention and treatment of various diseases. Even with the rapid advancement of synthetic pharmaceuticals, plant-derived medicines continue to play a significant role in m...

COMPREHENSIVE ANALYSIS OF THE ANTI-INFLAMMATORY POTENTIAL OF KSHARAGAD EXTRACTS: AN INVITRO STUDY

Inflammation is a protective response of the body against harmful stimuli such as infection, injury, toxins, and immune reactions. In Ayurveda, inflammatory conditions are broadly described under the concept of Shotha, which is caused by the imbalance of Doshas and other external...

FORMULATION AND EVALUATION OF MANTELUKAST SODIUM CHEWABLE TABLET

Montelukast sodium is a selective leukotriene receptor antagonist widely used for the prophylaxis and chronic management of asthma and allergic rhinitis. The present study aimed to formulate and evaluate Montelukast sodium tablets with improved tablet performance, rapid drug rele...

YUKTI TO NANO-PHARMACOLOGY: UNDERSTANDING ALPAMATRA MAHARTHATVAM AND THE THERAPEUTIC POTENTIAL OF RASAUSHADHIS

Background: Rasaushadhis represent a unique class of herbo-mineral formulations in Ayurveda, distinguished by three remarkable characteristics: administration in minute doses (Alpamatra), rapid therapeutic action (Kṣipramarogyadayitvat), and patient palatability (Arucheraprasanga...

NEW ONSET STATUS EPILEPTICUS AND MULTIFOCAL HAEMORRHAGE IN A YOUNG ADULT, A RARE CLINICAL PRESENTATION OF CNS VASCULITIS

Primary central nervous system vasculitis (PCNSV) is a rare inflammatory disorder affecting the blood vessels of the brain and spinal cord, without systemic involvement or underlying connective tissue disease. It usually presents with a wide range of nonspecific symptoms in the f...

MEDHYA RASAYANA WSR TO JATAMANSI FOR BUDDI, SMRITI & MEDHA

Jatamansi (Nardostachys jatamansi DC.) is a well-known Ayurvedic drug described for its Medhya (nootropic) and Manas-balancing properties. In the present era of increasing mental stress, anxiety disorders, and cognitive decline, there is a growing need to explore safe and effecti...

MANAGEMENT OF REFRACTORY SACROCOCCYGEAL PILONIDAL SINUS (SHALYAJA NADI VRANA) VIA MINIMALLY INVASIVE PARA-SURGICAL ABLATION USING SNUHI-APAMARGA KSHARSUTRA: A CARE-COMPLIANT CLINICAL CASE REPORT

Background: Sacrococcygeal pilonidal sinus disease (PNS) is a chronic inflammatory disorder predominantly affecting the young adult male population. Characterized by hair penetration into the subcutaneous tissues of the natal cleft, it yields blind epithelized tracts presenting w...

A RANDOMIZED OPEN LABELLED CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF AMLAKYADI GHRITA AND SHATAVARI GHRITA NASYA IN THE MANAGEMENT OF RAJONIVRITTIJANYA LAKSHANAS W.S.R. POST MENOPAUSAL SYNDROME

Background: Menopause is a physiological transition characterized by permanent cessation of menstruation due to ovarian follicular depletion and declining estrogen levels. The associated vasomotor, psychological, musculoskeletal, and urogenital symptoms substantially impair the q...

PREVALENCE AND ANTIBIOTIC RESISTANCE PATTERNS OF MULTIDRUG-RESISTANCE AND ESBL-PRODUCING GRAM-NEGATIVE BACTERIA ISOLATED FROM CLINICAL SAMPLES IN A TERTIARY CARE HOSPITAL

The problem of antimicrobial resistance (AMR) in Gram-negative bacteria has emerged as one of the major dangers to the whole world, threatening the efficacy of antibiotic treatment and raising the rates of morbidity, mortality, and expenditures connected with healthcare. It is es...

LARVAL EATING CAPACITY OF INDIGENOUS LARVIVOROUS FISHES AGAINST LARVAE OF CULEX QUINQUEFASCIATUS SAY IN FIELD OPERATIONAL CONDITIONS IN MONO DEPARTMENT IN SOUTH-WESTERN REPUBLIC OF BENIN, WEST AFRICA

Because of problems with insecticide resistance, alternative vector control methods are necessary. These methods include the use of biological control agents, such as larvivorous fishes. This study aimed to study larval eating capacity of indigenous larvivorous fishes against lar...

ROLE OF INDIVIDUALIZED HOMOEOPATHIC MEDICINE BARYTA MURIATICUM 30 IN THE MANAGEMENT OF ESSENTIAL HYPERTENSION: A CLINICAL STUDY

Background: Hypertension is one of the leading non-communicable diseases worldwide and a major contributor to cardiovascular morbidity and mortality. Despite the availability of effective antihypertensive drugs, many patients continue to experience poor blood pressure control bec...

MATERIALS FOR 3D PRINTING IN PROSTHODONTICS: ADVANTAGES AND DISADVANTAGES

Three-dimensional (3D) printing is a major innovation in digital prosthodontics, enabling the creation of accurate, customized dental restorations. The success of this technology relies heavily on the materials used, as their properties—physical, mechanical, biological, and aesth...

COMPLETE ERADICATION OF A LICHEN SIMPLEX CHRONICUS (LSC) LESIONIN A CASE RECACITRANT TO THERAPY WITH A COCKTAIL OF THERAPIES - A CASE REPORT

Lichen simplex chronicus delineate’s a kind of chronic localized pruritus with a secondary dermatitis, as well as one of the maximum frequent kinds of chronic itch situations, determined to influence greater than 10% of the general population as reviewed earlier. Here we report a...

MANAGEMENT OF PAKSHAGHATA WITH MUSTADI RAJA YAPANA BASTI: A CASE REPORT

Background: Pakshaghata is one of the major Vata Vyadhi described in Ayurveda and is clinically comparable to hemiplegia following ischemic stroke. Although advances in acute stroke management have improved survival, many patients continue to experience persistent neurological de...

PRAMANA SHARIR: THE TRADITIONAL AYURVEDIC METHOD OF BODY MEASUREMENT AND ITS RELEVANCE ACROSS VARIOUS FIELDS OF AYURVEDA

Anthropometry is the systematic and quantitative study of the human body and its physical dimensions. Derived from the Latin terms anthropos (human) and metry (measurement), it involves the measurement of body size, shape, and composition, including skeletal, muscular, and adipos...

UV SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION OF PREGABALIN

The objective of this study was to develop and validate a simple, sensitive, and economical UV-visible spectrophotometric method for the estimation of Pregabalin in bulk drug and pharmaceutical dosage forms. Pregabalin is commonly prescribed for the treatment of neuropathic pain,...

EFFICACY AND MECHANISMS OF PANCHAKARMA IN WOMEN'S HEALTH: A NARRATIVE REVIEW OF POLYCYSTIC OVARY SYNDROME, INFERTILITY, AND MENOPAUSAL DISORDERS

Gynecological and reproductive endocrine disorders, specifically Polycystic Ovary Syndrome (PCOS), female infertility, and menopausal disorders, pose significant global health challenges. Ayurvedic medicine offers systemic therapeutic interventions through Panchakarma (five biopu...