Research works

The HEADSpAcE Data Center: An international data and biospecimen resource for head and neck cancer translational research

Head and neck cancer (HNC) comprises a heterogeneous group of malignancies with substantial variation in incidence, risk factors, and outcomes across populations. Existing studies are often limited by regional scope or lack integration of epidemiological, clinical, and molecular...

Optimizing subtraction-based approaches in time-domain diffuse optics by a time-window analysis

Diffuse optics measurements performed in the time domain provide the highest information level, but are plagued by a low spatial resolution and significant sensitivity to superficial regions (e.g., extracerebral changes). Here we compare the two main analysis methods (namely, sta...

A mixed Petrov-Galerkin Cosserat rod finite element formulation

This paper presents a total Lagrangian mixed Petrov-Galerkin finite element formulation that provides a computationally efficient approach for analyzing Cosserat rods that is free of singularities and locking. To achieve a singularity-free orientation parametrization of the rod,...

Differentiable Bilevel Programming for Stackelberg Congestion Games

In a Stackelberg congestion game (SCG), a leader aims to maximize their own gain by anticipating and manipulating the equilibrium state at which the followers settle by playing a congestion game. Often formulated as bilevel programs, large-scale SCGs are well known for their intr...

Australia’s current wildfire crisis linked to colonial land-use change

The global wildfire crisis1 is often attributed to climate change, a framing that overlooks crucial historical drivers. Biomes at the forefront of this crisis, such as the temperate eucalypt forests of Australia, have seen alarming increases in large, intense wildfires in recent...

A thorium-229 optical nuclear clock with feedback loop

Abstract The laser-accessible nuclear transition in the thorium-229 isotope has been identified as a candidate for realizing an optical nuclear clock 1 that might outperform current optical clocks based on electron-shell transitions in atoms or ions 2 . It is expected to be more...

AI in supply chain risk assessment: a systematic literature review and bibliometric analysis

Abstract Supply chain risk assessment (SCRA) is pivotal for ensuring resilience in increasingly complex global supply networks. While existing reviews have explored traditional methodologies, they often neglect emerging artificial intelligence (AI) and machine learning (ML) appli...

Shayatin al-Ins: The Human Partners of the Satanic Franchise, Civilizational Mode Collapse, and the Architecture of the Endgame

Bismillahir-Rahmanir-Rahim This paper is dedicated to all the humans who are being subjugated and threatened by Satanists amongst the concealed beings, including Farwa Fatima Eraj of Bellaire, Texas. Her immediate family, and their extended families are at risk of being tortured...

Threshold effects of net interest margin on bank sustainable profitability in emerging economies

Abstract While sustainable bank profitability is critical for emerging economies, prior literature predominantly relies on linear models or arbitrary size classifications to evaluate the impact of Net Interest Margin (NIM), leaving scale-dependent structural breakpoints unexplore...

A conceptual methodological approach for addressing complex interdisciplinary challenges

Abstract Complex challenges are multi-faceted and, therefore, require the input of knowledge and expertise from different disciplines. However, the prevailing structures of academic institutions tend to be based on specialized disciplinary knowledge and expertise, rather than cro...

The Dunning–Kruger effect does not account for Covid-scepticism or vaccine hesitancy

Abstract Vaccine-scepticism and vaccine hesitancy are sometimes explained using the Dunning–Kruger effect (DKE), which posits that individuals with low knowledge in relevant domains are overconfident in their understanding. However, prior evidence often relies on discrepancy-base...

Contraception requirements in clinical HIV research: a qualitative analysis of adolescent perspectives from Malawi and Botswana

Abstract Background Clinical HIV research involving investigational or newly approved medications requires women of childbearing potential to use two forms of contraception to minimize fetal risk. These requirements also apply to adolescents who can become pregnant, yet ethical a...

The memory and purity cost of immediate delivery

How much memory does a device need to apply one quantum channel n times, if each output must leave before the next input arrives? The paper counts the qubits the device keeps, the qubits it exchanges for fresh ones, and the purity it is given, with error measured on the whole exp...

Assessment of infection prevention practices in office-based surgery: a multicentre regional audit

Abstract Background Office-based surgery (OBS) is increasingly used due to organizational constraints and perceived benefits. However, data on infection prevention and control (IPC) practices in OBS settings remain limited. This study aimed to assess the conditions in which OBS a...

Genome-wide identification and characterization of the galactinol synthase (GmGolS) gene family and its expression under drought, heat, and combined stress in soybean

Abstract Galactinol synthase (GolS) catalyzes the first committed step in raffinose family oligosaccharide (RFO) biosynthesis and is implicated in plant adaptation to abiotic stress. Although GolS gene families have been characterized in several plant species, a comprehensive gen...

From pelvic geometry to modal compliance: sex-specific deformation pathways in the human pelvic ring

Abstract Walking, posture and childbirth all depend on the pelvic ring, yet human pelvic dimorphism is usually interpreted from static birth-canal dimensions. We asked whether sex differences in pelvic function are explained by overall size and static pelvimetry or by available m...

Designing for access: implementation determinants of harm reduction vending machines in veterans supportive housing

Abstract Background Harm reduction vending machines (HRVMs) are an emerging strategy to provide convenient, low-threshold access to harm reduction and other health-related supplies, yet evidence and practical guidance on implementation, particularly in supportive housing and for...

Ant brain metabolomics reveals contrasting purine and amine dynamics in a reversible trematode-induced host manipulation

Abstract The neurochemical mechanisms underlying parasite-induced host manipulations remain poorly understood. Formicid ants infected with lancet fluke, Dicrocoelium dendriticum, attach to vegetation with their mandibles during cool conditions, facilitating ingestion by grazing m...

Effects of one night of sleep deprivation on single- and dual-task gait

Abstract Sleep deprivation (SDEP) impairs cognitive control, which may affect movements that rely on these processes, such as walking. To test whether gait changes after one night of SDEP reflect reduced cognitive capacity, we compared its effects with those of dual-task walking...

Five Maximal Incoming Classes Suffice: Exact Certificates and Structural Constraints for Seymour's Second-Neighbourhood Conjecture

This research preprint develops exact incoming-core certificates and structural restrictions related to Seymour's second-neighbourhood conjecture. Its principal computer-assisted theorem proves that every finite nonempty oriented graph with at most five inclusion-maximal incoming...