Research works

A hybrid metaheuristic for the family capacitated vehicle routing problem

Abstract The Family Traveling Salesman Problem (FTSP) seeks a minimum-cost tour from a depot that visits a prescribed number of members of each customer family. This paper studies the Family Capacitated Vehicle Routing Problem (F-CVRP), a generalization of the FTSP in which custo...

Impact of plasma conditioning-state evolution on Cl2/Ar plasma-assisted Si atomic layer etching

Plasma-assisted atomic layer etching (ALE) requires tightly controlled plasma conditions to achieve reproducible self-limiting material removal; however, the temporal stability of conditioned plasma environments and their influence on etching behavior remain insufficiently unders...

Turbidity Spikes: Fact or Fiction?

High‐frequency turbidity monitoring often reveals short‐duration spikes that may not reflect actual particulate events, creating challenges for accurate interpretation. A practical analytical approach can help distinguish true turbidity excursions from false positives.

Instability of natural convection in a vertical flat porous microchannel

Purpose This paper aims to focus on the hydrodynamic stability of steady-state natural convection inside a vertical flat porous microchannel. The main objective is to investigate the transition conditions from stable to unstable flow under the Boussinesq approximation, explicitly...

EMS response time and patient outcomes in high-acuity emergency responses: a Danish matched cohort study

Emergency medical services (EMS) provide prehospital care. To reduce response times, ambulances may use lights, sirens, and traffic exemptions, increasing risks for EMS personnel and other road users. Additionally, predefined response time targets may lead to inefficient resource...

Gut microbiota profile in school-aged children with vitamin A depletion and vitamin E deficiency: A cross-sectional study

Vitamin A (VitA) and vitamin E (VitE) deficiencies can result in significant health consequences in children. The role of the intestinal microbiota in these vitamin deficiencies has been scarcely explored. This cross-sectional study aimed to analyze the relationship of VitA deple...

Phi-Resonant Octonion Decomposition of E8 Root Vectors — E8 Intelligence Research

The 240 E8 root vectors decompose naturally into 8 octonion-dimensional layers where each layer's resonance frequency follows φ^n scaling from the 132Hz base, creating a Fibonacci-coherent harmonic lattice. The 344 Hz coherence phase transition emerges precisely at n=6 (132 × φ⁶...

Family Gatekeeping in Antenatal care Decision-Making: A Qualitative Study among Women in Rural Sangareddy District, Telangana, India

Abstract Background: Family members, particularly mothers-in-law and husbands, play crucial roles in maternal healthcare decisions in rural India. Understanding these dynamics is essential for designing effective maternal health interventions in Telangana, where maternal mortalit...

A Bilinear Residual Strength Model for Concrete Subjected to Fatigue Loads Based on Discrete Element Virtual Tests

Abstract Accurate assessment of fatigue residual strength is essential to ensure the safety and reliability of concrete structures given long-term fatigue loads. This study proposes a practical model for predicting concrete’s fatigue residual strength, which differs from conventi...

Rational Engineering of Carboxylic Acid Reductase for Improved Catalytic Efficiency and Substrate Tolerance Enabling Green Vanillin Biosynthesis

Abstract Vanillin is a high-value natural aromatic compound widely used in food, flavor, and pharmaceutical fields. Carboxylic acid reductase (CAR)-catalyzed vanillic acid bioreduction offers a green vanillin biosynthesis route, yet low catalytic activity and severe substrate inh...

Fluctuations of micronutrients during pregnancy in Lianyungang, Jiangsu, China: A prospective longitudinal cohort study

Pregnancy is accompanied by substantial physiological adaptations that may alter maternal micronutrient concentrations. A prospective longitudinal pregnancy-neonatal cohort of 51 healthy pregnant women was established at 6–8 weeks of gestation in Lianyungang, Jiangsu, China, conf...

Compartment-Specific Bacterial Communities and Their Functional Potential in the Desert Plant Citrullus colocynthis

Plants inhabiting arid and semi-arid ecosystems rely on their associated microbiota to withstand drought, heat, salinity, and nutrient limitation. We investigated the bacterial communities associated with the foliar tissues, roots, and rhizospheric soil of the desert plant Citrul...

Electoral reforms rejected: Partisan cues in an anti-party context

Proposals to change how parties functioned in elections appeared on several American states’ ballots in 2024, often bundling nonpartisan primaries (NPPs) with ranked choice voting (RCV). Given the complexity of the proposals, voters faced a difficult task and may have relied on c...

The effects of a lipid-based nutrient supplement intervention on DNA methylation in Bangladesh : insights from the Rang-Din Nutrition Study

Chronic undernutrition remains a major global health concern, particularly in early life. During this time, the resulting growth restriction and faltering are most responsive to nutrition interventions and consequential for health across the life course. Small-quantity lipid-base...

Clinical characteristics and outcome of a cohort of CLL patients with BTK T474 gatekeeper mutation

BTK T474 gatekeeper mutations confer resistance to both commercially approved covalent and non-covalent BTK inhibitors (BTKis) in chronic lymphocytic leukemia (CLL), yet their clinical implications remain poorly characterized. While pirtobrutinib was developed to overcome resista...

Prognostic Significance of Contrast Enhancement in Newly Diagnosed Grade 2 IDH-mutant Glioma

Abstract Background Contrast enhancement is generally considered an adverse prognostic feature in adult glioma. However, its significance in newly diagnosed grade 2 IDH-mutant glioma remains uncertain, with important implications for use of the mutant IDH inhibitor vorasidenib. W...

Cold-Water Immersion Does Not Improve Running Performance During Intensified Training.

The aim of this study was to investigate whether daily post-exercise cold-water immersion (CWI) preserves high-intensity running performance and modulates physiological and perceptual stress responses during an eleven-day intensified training period with limited recovery. Sevente...

Deconstruction of Hemp Stalks by Hydrated Deep Eutectic Solvents for Lignocellulosic Nanofibrils Preparation

Abstract The compact hemicellulose and lignin network in hemp stalks restricts fiber nanofibrillation and dispersion stability. Herein, a molecular simulation-guided hydrated deep eutectic solvent (H-DES) strategy was developed for biomass deconstruction and lignocellulosic nanof...

Comparing Human Gaze and Vision–Language Model Saliency Predictions in Safety-Relevant Scenes

Human visual attention plays an important role in how people perceive and respond to environments containing potential risks. It is unclear whether vision–language models (VLMs) can predict where people look in such scenes. This exploratory study compares human gaze with VLM sali...

The New Era of Metrology: What Lies Ahead for National Metrology Institutes?

This article examines the strategic implications of the 28th General Conference on Weights and Measures (CGPM) for the future of National Metrology Institutes. It focuses particularly on the digital transformation of the global metrology system and explores how developments such...