Research works

Multi-trait assessment of Meloidogyne incognita resistance in developed Cucumis spp. inbred lines: horticultural, physiological, biochemical, and histological insights

This study aimed to develop nematode-resistant inbred lines from Cucumis sativus, C. sativus var. hardwickii, and C. metuliferus, and to elucidate their resistance mechanisms against Meloidogyne incognita. Three parental genotypes were self-pollinated across five generations, wit...

Single-Chain Persistence Theory I: The Persistence Chain — From Genes to Memes (A Unified Inductive Framework from the Origin of Earth Life to Human Civilization)

We present Volume I of the Single-Chain Persistence Theory (SCPT-I): the evolutionary history of Earth life can be uniformly summarized as the persistence of a host-transiting information structure — the persistence chain — carried successively by genes (since ~4.0 Ga) and by mem...

Fostering Computational Thinking for an Adaptive Construction Workforce: Experimental Study of VR-Based Human–Robot Interaction

Abstract Construction work is becoming increasingly technology-intensive, requiring transferable skills that enable effective human–robot interaction (HRI). We designed and evaluated a virtual-reality (VR) training environment that pedagogically integrates computational thinking...

A Multi-Modal Pre-training Framework-Driven Active Learning System for Enhanced Protein Evolution of Cs CE

Abstract Protein language models have shown strong potential in modeling fitness landscapes for directed evolution; however, their predictive accuracy and generalization to unexplored sequence space remain limited under few-shot learning conditions. Here, we present MmALS (Multi-...

On the relevance of serial cyclone clustering for Arctic sea ice

Abstract Short-term changes in Arctic sea-ice concentration (SIC) are largely driven by weather, and strong ice loss typically occurs during intense Arctic cyclones causing unusually warm and stormy conditions. Such conditions are prolonged when several cyclones follow rapidly on...

Flexural strengthening of RC beams with NSM technique by vertical and inclined orientation of CFRP laminate

Abstract Retrofitting of reinforced concrete (RC) beams with FRP materials addresses issues of structural deterioration, offering a robust alternative to traditional steel reinforcement. This study experimentally investigates the flexural strengthening of RC beams using near-surf...

Menstrual and Reproductive Function Before and After Metabolic Bariatric Surgery

Abstract Aims To evaluate the impact of metabolic bariatric surgery on menstrual function, hormonal profiles, and reproductive health in women of reproductive age. Materials and methods In this prospective cohort study, women aged 18–45 years undergoing Roux-en-Y gastric bypass o...

Maximal Compound Curvature as a Complete Observable for Finite Partition Functions

Let $Z^g(\beta)=\sum_{j=1}^{m}g_j e^{-\beta e_j},$ $\qquad 0<g_j,\qquad e_1<\cdots<e_m,$ be a primitive finite weighted partition function. Its Hankel compound partition functions are $\tau_r^g(\beta)$ $=\det\!\bigl(M_{a+b}(\beta)\bigr)_{a,b=0}^{r-1},$ $\qquad$ $M_n(\beta)=\sum_j...

Medical information and decision-making in palliative cancer: a qualitative study of patients’ perceptions, needs, and preferences regarding physician communication

BACKGROUND: Patients with advanced cancer are frequently confronted with complex treatment decisions in the context of high emotional burden and potential limited prognostic benefit. Physician communication and the provision of medical information are therefore central to informe...

The impact of twine materials on the catch efficiency of abandoned, lost or otherwise discarded fishing gear (ALDFG) on crustaceans: an experimental study from Turkish inland set net fishery

Context Abandoned, lost or otherwise discarded fishing gear (ALDFG) represent a persistent pollution source in freshwater ecosystems, continuously capturing crustaceans long after being converted into ghost nets. Aim This study aims to experimentally determine the effects of the...

Emerging innovations in movement ecology to address planetary challenges

Abstract Movement ecology—the study of how and why animals move within their environments—stands to offer transformative insights into our rapidly changing world, with benefits for both nature and people. Here, we present the first global horizon scan for movement ecology, engagi...

Scaling up fabrication of thin-film nanocomposite (TFN) membranes: Methods, challenges, and applications

Abstract Thin-film nanocomposite (TFN) membranes have received significant attention because of their excellent separation performance, structural flexibility, and tunability. As the demand for high-efficiency membrane technologies in industry grows, it becomes imperative to tran...

Enhancing energy efficiency in crude distillation units via process simulation and SQP-based optimization

Abstract The paper introduces a unique approach combining Aspen HYSYS simulation, actual refinery operating data (Basrah refinery), ASTM D86-based validation, and sequential quadratic programming (SQP) optimization into one practical framework in the context of energy optimizatio...

Platelets as regulators of anti-tumor immunity: mechanisms and clinical implications

Platelets are increasingly recognized as important contributors to tumor progression and metastatic dissemination. Platelets facilitate cancer cell survival, their safe transit through the hostile bloodstream, arrest at distant organ sites, and ultimate outgrowth into metastatic...

Maximal Compound Curvature as a Complete Observable for Finite Partition Functions

Let $Z^g(\beta)=\sum_{j=1}^{m}g_j e^{-\beta e_j},$ $\qquad 0<g_j,\qquad e_1<\cdots<e_m,$ be a primitive finite weighted partition function. Its Hankel compound partition functions are $\tau_r^g(\beta)$ $=\det\!\bigl(M_{a+b}(\beta)\bigr)_{a,b=0}^{r-1},$ $\qquad$ $M_n(\beta)=\sum_j...

In-depth characterisation of the tumour microenvironment reveals HHV-8-dependent immune regulation in HIV-associated and classic Kaposi sarcoma

BACKGROUND: Kaposi's sarcoma (KS) is the most common malignancy occurring in people living with HIV (PLWH). The clinical course of KS in PLWH established on combined anti-retroviral therapy (cART) resembles that of classic KS. OBJECTIVES: To compare the clinical and biological ch...

Pit stop off the humpback highway: multi agency response to a sub-adult humpback whale Megaptera novaeangliae in Sydney Harbour, Australia

The east coast Australian humpback whale Megaptera novaeangliae population continues to recover post-whaling and is now estimated to be at least 50,000 individuals. The combination of population growth and increased human activities within coastal environments means there is a hi...

Cumulative non-high-density lipoprotein cholesterol exposure and residual cardiovascular mortality risk in patients with peripheral artery disease

Abstract Background Individuals with peripheral artery disease (PAD) face substantial residual cardiovascular risk despite lipid-lowering therapy. Non-high-density lipoprotein cholesterol (non-HDL-C) has been recognized as a more comprehensive marker of cardiovascular risk than l...

Targeting FibroblastActivation Protein for PrecisionMedicine

Conspectus The advancement of precision medicine depends critically on well-defined molecular targets. Pathologically activated fibroblasts drive disease progression in cancer, fibrosis and chronic inflammation through sustained inflammation, extracellular matrix remodeling and p...

Adult mental health service outcomes for patients of child and adolescent mental health services: a total Scottish birth cohort study

Abstract Child and adolescent mental health services (CAMHS) provide a critical opportunity for early mental health interventions. Evidence is still scare, however, on the long-term mental health outcomes of CAMHS patients, including their subsequent adult mental health service u...