Research works

Cataloguing & Referencing Art

In this document, we are creating a collection of objects, such as Internet Hyperlinks, Images, Quotes, etc. This activity is coherent with Mathematics Axiomatic Rules: At the beginning, there was an empty set, and the collection of objects create non-empty sets.

Oligodendrocyte Lineage Dysfunction in Alzheimer’s Disease: A Bidirectional, Stage-Dependent Account

Alzheimer’s disease (AD) has traditionally been framed as a neuronal disorder, yet white matter and myelin abnormalities are consistently detected in the preclinical period, before overt amyloid pathology or cognitive decline. This temporal relationship suggests that oligodendroc...

A Metal–OrganicFramework-Based ElectrochemiluminescenceImmunosensor with Dual Quenching via Resonance Energy Transfer andRadical Scavenging

Abstract This study reports a novel electrochemiluminescence (ECL) immunosensor designed for the highly sensitive detection of alpha-fetoprotein (AFP) via a dual quenching strategy. The sensor architecture employs an aluminum-based metal–organic framework (MIL RuMOF@Pt) as the EC...

Lipidomic and transcriptomic remodeling underlies early retinal pathogenesis in dry age-related macular degeneration

Abstract Dry age-related macular degeneration (AMD) is initiated by retinal pigment epithelium (RPE) dysfunction, yet early metabolic mechanisms linking RPE injury to photoreceptor dysfunction remain unclear. Using a physiologically relevant mouse model, we performed cell-type–re...

Trustworthy Deployment of LLM-Based RAG Systems for Small Businesses: A Security and Confidence-Aware Framework †

Small and medium-sized enterprises (SMEs) are increasingly deploying Large Language Model (LLM)-based agentic systems to support customer service and internal knowledge management. However, practical deployment of retrievalaugmented generation (RAG) systems continues to be challe...

Peripheral Nerve Entrapment Mimics of Overuse Syndromes

Repetitive use injuries are commonly seen by musculoskeletal providers, usually in the form of tendinopathies. However, focal peripheral nerve entrapment can mimic or coexist with tendon pathology, particularly when weakness, sensory symptoms, or imaging findings are subtle or no...

Real-world efficacy and safety of sofosbuvir/velpatasvir/voxilaprevir in treatment-naive and treatment-experienced chronic hepatitis c patients: a single-center study

Although international guidelines primarily position the sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) combination as a salvage therapy for treatment-experienced patients, specific national reimbursement policies in Türkiye have uniquely positioned this regimen as a first-lin...

Cardiac interoception as a mechanistic link between congenital mitral valve prolapse and anxiety disorders: from circuit dissection to neurotechnological modulation

Abstract Background Interoception represents the brain’s ability to sense and interpret internal bodily signals, integrating cardiovascular, autonomic, and cortical processes to maintain homeostasis and shape emotional states. Cardiac interoception links physiological signals wit...

Revealing spatial patterns and depth-dependent controls of soil organic carbon density across China using interpretable machine learning

Abstract Soil organic carbon density (SOCD) is a key indicator of soil health and a critical component of terrestrial carbon storage, yet its large-scale spatial organization and environmental controls remain insufficiently understood. Here, we assessed national-scale patterns an...

Evidence for non-mucinous pulmonary lesions with adenocarcinoma in situ morphology exceeding the current 3 cm WHO threshold

CONTEXT: The World Health Organization (WHO) recognizes adenocarcinoma in situ (AIS) of the lung for tumors up to 3 cm in size. Larger tumors with a lepidic growth pattern are classified as invasive lepidic predominant adenocarcinoma. OBJECTIVE: The aim of this study was to demon...

Redox-Active Ligand-AssistedRuthenium-Catalyzed Lemieux–Johnson-TypeOxidation of Olefins for Aldehyde Synthesis

Abstract This work presents a ruthenium complex catalyst bearing redox-active ligands for highly selective oxidative cleavage of alkenes. The ligand serves as a dynamic electron reservoir with two core functions. Reversible electron transfer between the ligand and the Ru center g...

Surveys of Hintang standing stone sites and excavations at Site 7A, Houaphanh, Lao PDR

Archaeological research conducted by a Lao-Australian team at the Hintang (standing stone) sites in Houaphanh Province, Laos, has permitted the geolocation of standing stone groups and the recovery of excavated archaeological remains from one site, including earthenware ceramics,...

Evidence-based interventions for vocational recovery in first-episode psychosis: A meta-analysis of employment and education rates

Background: Young people with first-episode psychosis experience high rates of disruption in work and education and consistently describe vocational participation as a core priority of recovery. This meta-analysis aimed to evaluate the effectiveness of evidence-based intervention...

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The impact of climate change on the river basins of Parma (Italy) and Kamianka (Ukraine): a comparative analysis

Abstract This study compares climate change impacts on two contrasting European river basins: the Parma River (Italy) and the Kamianka River (Ukraine) representing different ecoregions and climatic zones. The research used QGIS tools and satellite data from Landsat Collection 2 L...

From male caduco to altered consciousness: two Medici recipes through the lens of modern consciousness science

This article examines two therapeutic recipes from the collection of Anna Maria Luisa de' Medici (1667-1743), the last Medici princess: the Polvere da Infantiglioli against the falling sickness (male caduco) and a preparation of amber essence. Together, they provide a case study...

Patterns of peer bullying among adolescents: the role of BMI and socioeconomic factors – a cross-sectional study in Turkey

OBJECTIVES: Peer bullying represent significant public health challenges with profound implications for adolescent psychosocial development. This study investigates the frequency of traditional and cyberbullying among adolescents, specifically examining how BMI and socioeconomic...

Exploratory assessment of the clinical significance of the collateral system between the superior mesenteric artery and inferior mesenteric artery in laparoscopic rectal cancer surgery

Abstract Background Rectal cancer (RC) is a common and lethal malignant tumor, and surgical treatment is essential. The collateral system between the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA) remains controversial, and its potential clinical significan...

Category-based attention facilitates the recognition of actions

Abstract Action recognition relies on efficiently prioritizing relevant sources of information. This study examined the degree to which category-based attention facilitates the identification of basic action categories (climb, jump, run, walk) depicted as static avatar images (Ex...

Treatment with Cistus incanus and Rosmarinus officinalis reduces inflammatory processes in an in vitro virus mimicry approach

Acute respiratory viral diseases caused by single-stranded RNA (ssRNA) viruses like influenza A infection occur frequently in all age groups, with significant impact on morbidity and mortality worldwide. The severity and burden of the disease is tightly connected to host inflamma...