LINGO1-targeted antibody-drug conjugates improve efficacy and tolerability of antineoplastic therapies in Ewing sarcoma models
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Abstract
We reported LINGO1 as a potential marker on Ewing sarcoma cells that could enable targeted drug delivery, improving treatment effectiveness while reducing side effects.
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Authors: Zhichuan Zhu, Yusha Liu, Yu Deng, Zhijun Li, Albert S. Baldwin, Pengda Liu
Institutions: Cancer Research And Biostatistics, University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Segeberger Kliniken, Institute of Molecular Biology and Biophysics