Uppsala University

A Fourth Order Cut Finite Element (cutFEM) Method for the Wave Equation using the Modifed Equation Approach

Abstract A symmetric bilinear form corresponding to the biharmonic operator is combined with a corresponding bilinear form for the Laplacian to create a temporally 4th order corrected leap-frog scheme for the wave equation. The boundary conditions are imposed weakly, which allows...

Prognostic value of risk factors for ischaemic and major bleeding events in chronic coronary syndrome: a SWEDEHEART registry study

AIM: In patients with chronic coronary syndrome, risk factors for ischaemic events and bleeding tend to overlap. However, the combined effects of these factors have scarcely been studied in contemporary real-world settings. METHODS: All patients in Sweden undergoing elective PCI...

Quantification of Urinary NGAL Using Volumetric Dried Urine Sampling

Objective: To evaluate the measurement of urinary neutrophil gelatinase-associated lipocalin (NGAL) from dried urine samples collected using Capitainer qDBS discs compared with liquid urine. Methods: Eighty urine samples from children aged 0–18 years were analysed. NGAL concentra...

Association between urbanicity–cooking fuel type and self-reported respiratory symptoms as a proxy for acute respiratory infection symptoms among children under two years across ten East African countries

Abstract Introduction Evidence remains limited on how urbanicity modifies the relationship between household cooking fuel type and respiratory symptoms in young children in low- and middle-income countries (LMICs). This study examined the prevalence of cough and dyspnea across te...

Genome-wide association study of image-based emphysema scoring in the Swedish CArdioPulmonary bioImage Study (SCAPIS) suggests two new risk loci in smokers

Abstract Background Despite the high prevalence and clinical significance of emphysema, few genetic risk loci have been consistently replicated. We conducted a genome-wide association study (GWAS) of CT-based emphysema, with a particular focus on non-smoking-related genetic deter...

Children's lived experiences of transitioning between hospital and home in paediatric oncology: A qualitative study

PURPOSE: Advances in paediatric oncology have improved survival rates, but intensive treatments and frequent hospitalisations disrupt family life. Hospital-to-home transitions are critical yet underexplored in the cancer trajectory. Existing models of discharge planning primarily...

Functional differences of Munc18 isoforms reflect their affinities for the exocytosis site

Abstract The SM-protein Munc18 and its binding partner syntaxin are crucial for two distinct steps of regulated exocytosis, docking of secretory granules at the release site, and priming reactions that prepare docked granules for Ca 2+ dependent fusion. Both proteins cluster simu...

Combined fibre-optic sensing and nodal recorders for active-source seismic characterization of mine tailings

Abstract As the mining industry shifts toward more responsible and lower-impact practices, mine tailings are increasingly regarded as a secondary resource that can be sourced into the raw-material supply chain. However, limited knowledge of subsurface geometry at many historical...

Solving problems increases provisioning efficiency, enhancing reproductive success in male great tits

Abstract The ecological and selective processes acting on cognitive traits have received recent attention because of the potentially key role of cognition in rapid behavioural adjustments in response to environmental variation. Innovation, a cognitive process involved in the deve...

The influence of age on emotion-regulatory strategies, emotional work demands, and health/work outcomes: a systematic PRISMA literature review with narrative synthesis

BACKGROUND: An increasing age of the workforce necessitates a better understanding of age-related differences in emotions at work to inform age-inclusive workplace policies and practices. This review critically evaluates how age relates to emotion-regulatory strategies at work (e...

The Zooplankton International Geospatial dataset: A global repository of spatiotemporal freshwater zooplankton community composition data from lakes and reservoirs to support ecological research

Abstract Zooplankton transfer substantial energy in aquatic food webs and are used as indicators of environmental change. Syntheses of zooplankton community dynamics globally require datasets that span a wide range of environmental gradients; however, these datasets are limited d...

CO 2 ‐to‐CO Electrochemical Conversion With an Fe(I) Porphyrin Complex in Water

ABSTRACT Iron porphyrin complexes constitute a well‐established and versatile class of molecular electrocatalysts for the reduction of CO 2 to CO. In both organic and aqueous media, the reaction mechanism is typically proposed to involve the interaction of CO 2 with a formally de...

Receiver function imaging reveals Pyrenean-style crustal wedging in the Western Carpathians

The Alpine−Tethys suture in the Western Carpathians records the collision between the northern European passive margin and the Adria-derived Alps−Carpathians−Pannonian (AlCaPa) tectonic unit. Previous tectonic models, largely based on indirect evidence, proposed complex configura...

Introducing HUM19

Abstract This report introduces the HUM19 corpus of 19th century British and Irish novels and describes its construction. We characterise the HUM19 corpus as a specialised reference corpus that can be used both as a comparator against which other corpora or texts may be compared...

Restoring microbial relations and landscapes: a relational conceptual framework for fermentation, culture, and health equity

Introduction: Biodiversity decline in both external environments and internal human microbiomes indicates disrupted relationships between humans, microbes, food systems, and ecological landscapes. These interconnected landscapes are important for global health and sustainability...

Imaging of ROR1 expression in tumors using radiolabeled affibody molecules

Abstract Purpose Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an attractive molecular target for anti-tumor therapies undergoing late-stage clinical development. Quantitative imaging of ROR1 expression could enable identification of patients likely to respond to such...

Drug stock-outs in HIV, tuberculosis, and malaria programs: a systematic review

Background Stock-outs of antiretroviral, anti-tuberculosis, and anti-malarial medicines remain a major challenge in low- and middle-income countries, affecting both health systems and patient outcomes. This systematic review aimed to synthesize evidence on the causes, consequence...