UNSW Sydney

The effect of 0.1% topical ciclosporin a for 12-weeks on the ocular surface innate and adaptive immune response in dry eye disease: protocol for a randomized controlled clinical trial

Background Ocular surface immune cells and pro-inflammatory cytokines have been reported to be increased in Dry eye disease (DED). Immunosuppressive agents such as topical cyclosporine A (CsA) can inhibit dendritic cell and T cell activation. However, CsA’s impact on ocular surfa...

A novel geofoam-geogrid composite for protecting buried pipelines against blast loads

This study investigates the performance of a novel geofoam-geogrid composite in mitigating the impact of surface and subsurface blasts on API-× 65 steel pipelines buried 2 m below ground level. A 3D nonlinear finite element method was employed to analyze the effects of blast char...

Women’s cursing practices in the Lari language

Abstract This paper aims to investigate the structure and pragmatics of cursing expressions in Lari, an endangered language spoken in the south of Iran as well as other countries such as the United Arab Emirates (UAE) and Kuwait. This study adopts a descriptive approach in method...

RNA-guided transposases: the successors to CRISPR

CRISPR undoubtedly transformed genome editing, but it left two crucial problems unsolved. Cas nucleases cut the chromosome and leave the cell to repair the break, an error-prone process that is inefficient for installing new DNA, and Cas9 is large relative to the cargo that viral...

The Development and Validation of a Preliminary Model for Classifying Technology Facilitated Child Sexual Exploitation and Abuse by Men in the General Population

The current study aimed to develop and validate a preliminary model for classifying self-reported TF-CSEA perpetration in general population samples. Data were based on census-weighted samples of adult men from Australia ( n = 1,939), the U.K. (n = 1,506), and the U.S.A. ( n = 1,...

Probing context-sensitive expectations through user-driven personality configuration in conversational AI

Abstract Conversational agents are increasingly expected to adapt across contexts and evolve their personalities through interactions, yet most remain static once configured. We present an exploratory study of how user expectations form and evolve when agent personality is made d...

Prenatal substance exposure and developmental outcomes at age 5: a population-based cohort of 260 000 children in New South Wales, Australia

Objectives We quantified the risk of developmental support needs at school entry among children with and without prenatal substance exposure, to inform service delivery initiatives in the first 2000 days of children’s lives. Methods We assembled a cohort using population-level pe...

Ferroelectric phase transformations in the spinodal decomposition framework

This perspective reviews phase transitions in ferroelectric topologies through a spinodal decomposition framework. It focuses on the thermodynamic and kinetic pathways that determine non-trivial topological phases and their evolution. By drawing analogy to chemical spinodal decom...

Short fire-interval and drought lead to decline in an obligate seeding Banksia

Context Fire frequency is predicted to increase with climate change and represents a major threat to plant communities around the world. Despite this, there are few published examples quantifying impacts of short fire-intervals, even for those species most at risk. Aims We examin...

DOES ROBOTIC-ASSISTED SURGERY OR FUNCTIONAL ALIGNMENT IMPROVE INTRAOPERATIVE BALANCE IN TOTAL KNEE ARTHROPLASTY? A SECONDARY ANALYSIS OF THE RASKAL TRIAL

Abstract Background This study assessed rates of imbalance in total knee arthroplasty (TKA) and its effect on patient-reported outcome measures (PROMs), comparing robotic-assisted surgery (RAS) versus computer-assisted surgery (CAS), and functional alignment (FA) versus mechanica...

Measurement of cervical cancer quality indicators using a population-based linked dataset in New South Wales, Australia

The aims of this study were to assess feasibility of measuring cervical cancer quality indicators (QIs) using a population-based linked dataset, assess the quality of care in the treatment of cervical cancer at a population level and to evaluate whether any sociodemographic varia...

Why She Stays: A Role-Based Analysis of Women’s Motivations in Construction

The construction industry is actively promoting female participation, but the motivation to drive their entry and stay, particularly into different job roles, remains underexplored. Previous studies typically treated extrinsic motivation as a single, undifferentiated construct. T...

High-Performance and Scalable Hydrovoltaic Power Generation via Seawater-Driven Ion Transport in 3D Porous Non-Woven Fabrics

This study reports a simple, high-performance, and cost-effective hydrovoltaic power generator driven by natural seawater. The device combines 3D porous non-woven fabrics with asymmetric copper–aluminum electrodes, offering flexible design and excellent environmental adaptability...

Heat-Transfer-Driven Voxel-Based Simulation: An Exploratory GPU-Accelerated Framework for Urban-Scale 3D Fire Spread

The rapid growth of high-resolution 3D voxel datasets derived from LiDAR, BIM, and urban digital twin platforms has created new opportunities for volumetric environmental simulation. However, existing fire-spread models are often surface-based or computationally intensive for lar...

Respirable Particulate Matter Induces Natural Killer Cell Dysfunction via Oxidative Stress-Mediated Lysosomal and Mitochondrial Injury: Implications for Mineral-Rich Mining Dust Exposure

Abstract Epidemiological and occupational studies increasingly link respirable particulate matter (PM), including mineral dust, exposure with elevated lung cancer risk, yet the immunological mechanisms underlying these associations remain poorly defined. In this study, we investi...

Multicentre Prospective Cohort Study of Continuous Antibiotic Infusion via Peripheral Intravenous Cannula in the Hospital in the Home Setting

Importance Continuous intravenous (IV) antibiotic infusion via peripheral intravenous cannula (PIVC) is utilised in some Hospital in the Home (HITH) services, but current Australian guidelines advise against this practice due to concerns about device failure and complication risk...

Diversity and Plasticity of Hydraulic Traits Across a Relative Moisture Supply Gradient: Results From Multiple Common Gardens

ABSTRACT Maintaining cellular hydration is essential for plant metabolic activity and carbon gain. Plants typically maintain hydration through efficiency of water transport networks, the ability to avoid network disruption, and retention of water via accumulation of osmotica. Giv...

Debt, Power, and Play: Modeling Sovereign Restructuring with Creditors and the IMF

This paper develops a continuous-time stochastic model of sovereign debt sustainability with endogenous restructuring and an active multilateral lender. The sovereign interacts with two heterogeneous creditor classes and the IMF within a dynamic stochastic game featuring jump–dif...

Heads or tails: selective body part feeding by scavengers across species and season

Abstract Many wild species regulate their nutritional intake and respond dynamically to nutritional stressors, yet little is known about the targeted feeding behaviours of carnivorous scavengers—specifically, which body parts they consume. Using camera traps to monitor 40 experim...

Potential predation impacts of invasive non-native rodents (black rats) on plant species from a Pacific Island (Lord Howe Island, Australia)

Context Invasive non-native rodents pose a significant threat to a range of plants on oceanic islands, particularly where there are high levels of endemism. Aims On Lord Howe Island in the western Pacific Ocean, prior to rodent eradication measures, we used selective caging and c...