UNSW Sydney

Chemovaccination with a late-liver-stage antimalarial induces durable immunity against malaria

Plasmodium falciparum sporozoite vaccines, in which parasites are attenuated at the liver stage, provide high efficacy but require complex manufacture and intravenous administration of high sporozoite doses. We found that a single low-dose P. berghei sporozoite exposure (intraven...

Genomic catalogue of giant viruses reveals expanded diversity and functional potential

Nucleocytoplasmic large DNA and Mirusviricota viruses exhibit taxonomic richness which continually expands due to metagenomic sequencing. Here we curate a database of giant virus metagenome-assembled genomes (GVMAGs V2), comprising 8,508 species-level representatives from 18,727...

John Stewart Turner

Abstract Black and white portrait showing John Stewart Turner, an older man with a receding hairline, wearing thick-framed glasses, a light-colored textured suit jacket, a white shirt, and a light-colored tie with a dotted pattern. He smiles slightly and looks directly forward. B...

Prevalence and Determinants of Sexually Transmitted Infections Among Thai Men Who Have Sex with Men Enrolled in National Pre-Exposure Prophylaxis Program: A Real-World Cross-sectional Study

Background: Sexually transmitted infections (STIs) remain a major public health concern among men who have sex with men (MSM). This study estimated STI prevalence and associated factors among MSM enrolled in Thailand’s national pre-exposure prophylaxis (PrEP) registry under the U...

Multifactorial ecological framework for intestinal-type gastric cancer

Gastric cancer (GC) remains one of the leading causes of cancer-related mortality worldwide, with projections indicating increasing incidence and marked geographic variability across populations. Although multiple hypotheses have been proposed to explain this heterogeneity, inclu...

Everyday journeys, everyday risks: examining adolescent road safety knowledge, practices and perceptions in Delhi, India

Background Adolescents represent a high-risk group for road traffic injuries, particularly in rapidly motorising cities in India. This study aimed to document the travel patterns and understand the road safety knowledge, practices and safety perceptions of adolescents during thei...

Why Are Cascade Birth Interventions Rising?

The increasing use of birth interventions has prompted global policy and research focus. This study attempts to enhance our understanding of why this increase is occurring. Using a population-based dataset of over 1.3 million births in New South Wales, Australia (2004–2018), we i...

Maximising the ‘co’ in co-design through facilitator actions: co-designers’ perspectives on what makes their participation in co-design meaningful

Co-design is a participatory approach to service development and research that is increasingly expected within the mental health sector. It involves end users being involved throughout a design process, not simply by providing opinions, but through shared decision making. Evidenc...

Does TikTok promote or cannibalize music streaming? Estimands and identification with heavy-tailed outcomes

Abstract We study how TikTok affects demand for music on paid streaming platforms in the context of Universal Music Group’s (UMG) global withdrawal of its catalog from TikTok. Recent studies using this quasi-natural experiment have reached different conclusions about whether TikT...

A Stock Market Price Prediction Model Integrating a CNN–Transformer Dual-Channel Dynamic Attention Architecture

Stock market price prediction remains a persistent challenge owing to the non-stationarity, high noise content, and intricate spatiotemporal dependencies that characterize financial time series. Existing approaches typically excel at either local pattern extraction or long-range...

Optimizing Informed Consent for Australian Newborn Bloodspot Screening and Research: Consensus Workshop Insights and Recommendations

Informed consent is fundamental to Australian newborn bloodspot screening (NBS), but emerging genomic screening technologies pose new challenges to clinical care and research. Optimizing consent processes is necessary to support ethical practice and maintain public trust as NBS e...

Effects of Morning and Evening Narrowband Blue Light and Myopic Defocus on Axial Length in Humans

Purpose To investigate the effects of morning and evening narrowband blue light exposure on axial length, and to examine the short-term effect of morning blue light combined with myopic defocus on axial length.Methods For objective 1, 18 individuals underwent 60 minutes of narrow...

Numerical investigation of the energy absorption mechanisms of the selected ground support elements

Abstract Ground support systems are critical in ensuring safety while maintaining excavation stability to support continuous production. In burst-prone mines, these systems must also withstand dynamic loading and large deformation. To achieve this, underground mines employ a comb...

Health Care Stigma and HIV/Sexually Transmitted Infection Prevention Service Uptake Among Cisgender Men and Gender-Diverse Individuals Who Have Sex with Men in Five Asian Countries: Implications for Differentiated Service Delivery

Health care stigma remains a key barrier to HIV and sexually transmitted infection (STI) prevention, yet its effects may differ across health care systems. We examined associations between health care stigma and HIV/STI prevention service uptake across five Asian countries. A cro...

Transdiagnostic symptoms of psychopathology interact with changes in environmental uncertainty

Abstract Uncertainty is a potential driver of poor mental health outcomes, and uncertainty is mounting across domains of daily life. It remains unclear how symptoms of anxiety and depression emerge in response to uncertainty in real-life contexts. The current study investigated h...

Gender-affirming psychiatry: a minority stress and phenomenological framework for child and adolescent mental health

This perspective article introduces Gender Affirming Psychiatry (GAP), a conceptual framework that integrates queer phenomenology, the gender minority stress model, and gender-affirming care to guide psychiatric assessment, formulation, and treatment of transgender and gender div...

Molecular mechanisms of dust-induced lung disease: exploring the role of physicochemical composition and cellular pathways

Respirable dust and fibres in occupational settings are major contributors to lung dysfunction, imposing a significant societal burden. Following the ban on asbestos in most countries, silica and coal mine dust have emerged as primary concerns due to their abundance and persisten...

Narcissism re-framed as a superiority motive: unifying evolutionary and clinical perspectives

Objective Narcissism is commonly described through grandiosity, entitlement, admiration seeking, exploitation and impaired empathy. This perspective article proposes that these features can be clinically organised around a common function: the regulation of felt superiority. Conc...

Factors associated with bowel cancer screening participation among First Nations Peoples receiving home health care services in New South Wales, Australia

First Nations Australians consistently exhibit lower bowel screening participation rates than non-First Nations Australians. However, limited studies have been conducted to understand the factors associated with bowel cancer screening participation among First Nations Australians...

Issues in the clinical assessment and management of people living with motor neurone disease (MND): a survey of Australian healthcare professionals

Objective: To inform the development of the Australian MND Guideline, this study aimed to identify challenges Australian healthcare professionals (HCPs) face in the clinical assessment and management of people living with MND (plwMND) including where practice varies from evidence...