University of Padua

1-Piperidine Propionic Acid Inhibits PAR2/SerpinB3 Signaling and Reduces Glioblastoma Tumor Aggressiveness

Glioblastoma multiforme is the most aggressive primary brain tumor in adults, which displays extremely poor prognosis. Protease-activated receptor 2 (PAR2) and its downstream effector SerpinB3 are overexpressed in aggressive glioblastomas. In this study we evaluated the antitumor...

Feeding and Husbandry Practices in Pet Ferrets ( Mustela putorius furo ): A Cross‐Sectional International Study

ABSTRACT Background The domestic ferret ( Mustela putorius furo ) is an increasingly popular non‐traditional companion animal; however, limited information is available on how caregivers manage feeding and husbandry practices. Objectives This study aimed to investigate feeding an...

Early vs. Late Extubation After Bilateral Lung Transplantation: Predictors and Outcomes

Background: Early extubation after bilateral lung transplantation (LT) may reduce intensive care unit (ICU) complications, but evidence from heterogeneous real-world cohorts and of its impact on mid-term functional recovery remains limited. Methods: We conducted a single-centre o...

Vasoplegia in Cardiac Surgery and Mechanical Circulatory Support: From Cardiopulmonary Bypass to Advanced Circulatory Support Devices

Vasoplegia remains one of the most challenging and incompletely understood complications across the spectrum of mechanical circulatory support (MCS). Initially described following cardiopulmonary bypass, it is increasingly recognized in patients supported with veno-arterial extra...

Use of a nanosecond Q-switched 1064 nm Nd: YAG laser for photoaging management in Asian skin: a retrospective study

Facial wrinkles are a major concern in aesthetic dermatology, particularly in patients with darker phototypes, in whom laser treatments require careful parameter selection to minimize pigmentary adverse events. This retrospective study evaluated the effectiveness and tolerability...

Healing Following Endoscopic Reconstruction of the Anterior Skull Base in Patients With Sinonasal Malignancies

ABSTRACT Background Healing dynamics after anterior skull base (ASB) reconstruction following transnasal endoscopic surgery (TES) for sinonasal malignancies remain poorly characterized. This study aimed to describe the postoperative healing process, quantify time to healing, iden...

Post-Operative Magnetic Resonance Imaging of Canine Cervical Spine After Ventral Slot Surgery; Evaluation of the Porcine-Derived Hemostatic Compound Spongostan™ Specific Imaging Features

Porcine-derived gelatin sponge SPONGOSTAN™ is an adjunct material routinely used in neurosurgery. This study aimed to describe its MRI features, since its imaging features are not available yet in veterinary medicine. Post-operative MR images of dogs that underwent decompressive...

Moral emotion processing in euthymic bipolar disorder: insights from network analysis

Abstract Background Bipolar disorder (BD) is associated with facial emotion recognition (FER) deficits. Among these, impairments in recognizing moral emotions may be especially relevant to social dysfunction, but their relationship with brain structure remains poorly defined. Met...

Double functionalization in chitosan scaffolds for bone tissue engineering improvement

Abstract Chitosan is a natural polysaccharide produced by the deacetylation of chitin. It has been employed for several biomedical applications since it is biocompatible and biodegradable. In this work, two synthetic peptides were covalently grafted to chitosan to enhance cellula...

Vaccination in pediatric transplantation—General recommendations. A position paper by the European Reference Network TransplantChild

Infectious diseases remain a leading cause of morbidity and mortality among pediatric transplant recipients, despite significant advances in transplantation management. Vaccination is the most effective strategy to prevent infections; however, its efficacy is hindered in solid or...

Diosmin Attenuates Age-Associated Vascular Oxidative Stress and Endothelial Dysfunction in Aged Rats

Vascular aging is driven by a self-sustaining interplay between oxidative stress and chronic low-grade inflammation, collectively referred to as inflammaging. Diosmin, a citrus-derived flavonoid with antioxidant and anti-inflammatory properties, has not previously been investigat...

Fusion at scale: Critical enablers in global energy transitions

Fusion is a promising sustainable energy source that can potentially contribute to achieving the most ambitious climate goals with firm carbon-free baseload electricity. Due to recent advancements, fusion is transitioning from a purely research stage to a pre-commercialisation ph...

The Extended Kalman Filter for constraint enforcement in the forward dynamics of multibody systems

<title>Abstract</title> The forward dynamics of multibody systems is widely exploited in engineering applications to simulate the behavior of complex mechanical systems undergoing kinematic constraints. It relies on the integration of the equations of motion of the system. Howeve...

Scanner-Measured Hand Hygiene Performance After Automated Visual Feedback-Supported Training: A Multicenter Quality Improvement Project in Italian Hospitals

Background: Healthcare-associated infections (HAIs) remain a major patient safety issue, and hand hygiene (HH) is a key preventive measure. Technologies providing immediate visual feedback may support HH training by allowing objective assessment of hand-rubbing technique. Methods...

Nutritional Strategies for Recovery–Adaptation Coupling After Exercise: From Muscle Damage to Performance Remodeling

Background/Objectives: Recovery nutrition must restore near-term readiness without indiscriminately suppressing biological signals that contribute to repair and training adaptation. This review evaluates recovery–adaptation coupling (RAC) as a research framework and clarifies its...

Optimal investment and fair sharing rules of incentives in virtual renewable energy communities

Abstract This paper examines two interconnected challenges in Renewable Energy Communities (REC) optimization: investment in renewable technologies and equitable sharing of incentives, usually offered by a central authority. Focusing on a REC under the so-called virtual framework...

Benchmarking and assessment of image-based methods for particulate matter estimation: The AQpictures project

Abstract. Fine particulate matter (PM2.5) is a major air-quality and public-health concern, while conventional monitoring networks remain limited in coverage and costly to deploy and maintain. This work presents the AQpictures project, which investigates alternative low-cost moni...

Direct ink writing of geopolymer adsorbents: A review

Geopolymers (GPs) are amorphous aluminosilicate binders valued as low-cost adsorbents for their cation-exchange capacity, tunable porosity, and chemical stability. Direct ink writing (DIW) has recently emerged as a processing route to shape these materials into structured lattice...

Beam steering and radiation generation of electrons in bent crystals in the sub-GeV domain

Abstract We present an investigation into beam steering and radiation emission by sub-GeV electrons traversing a bent silicon crystal. Using 855, 600, and 300 MeV electron beams at the Mainz Microtron (MAMI), we explored orientational coherent effects in a 15- $$\upmu $$ <mml:mat...

A competency addition procedure for constructing minimal, yet maximally informative tests for skill assessment

Abstract Competence-based test development is a novel method for constructing tests that are as informative as possible about the competence state (the set of skills an individual possesses) underlying item responses. If desired, the tests can also be minimal, meaning that no ite...