University of Padua

Real-world Italian experience with asciminib in chronic myeloid leukaemia–chronic phase: case series and drug profile overview

Abstract Asciminib selectively targets the myristoyl pocket of ABL1, offering high specificity and a potentially improved safety profile. Its efficacy has been demonstrated in both clinical trials and real-world settings, including heavily pretreated patients and those with T315I...

Frailty and longitudinal pulmonary function trajectories in lung transplant recipients

Abstract Background Frailty is increasingly recognized as a marker of biological vulnerability associated with adverse clinical outcomes. Lung transplant recipients may be particularly susceptible to frailty, yet its impact on longitudinal pulmonary function improvement after tra...

Deterministic mean field games on networks and related optimal control problems

We study deterministic mean field games and related optimal control problems, with finite time horizon and a network as state space. An agent controls her velocity and, when she occupies a vertex, she can either remain still or enter any adjacent edge. The costs are continuous in...

Italian Fluvial Sediment Transport Database: a comprehensive hub for archiving and analyzing hydrological data

Fluvial sediment transport plays a key role in geomorphological and hydrological processes, influencing river morphology, watershed and coastal sediment balances, and the environmental response to climatic and anthropogenic changes. In Italy, the availability of homogeneous and l...

Epidemiology, impact on oncologic treatments, and management of community-acquired respiratory virus (CARV) infections in pediatric onco-hematology patients: a survey among Italian pediatric oncology hematology centres (AIEOP)

Abstract A survey was conducted across Italian Pediatric Onco‑Hematology centres to assess epidemiology of community‑acquired respiratory virus (CARV) infections, chemotherapy management, Oseltamivir use and vaccination policies. Most reported infections were mild and managed out...

Protein-Based Biomaterials for Bio-Optoelectronics: A Review of Bio-Integrated and Biodegradable Optodevices

Growing development of biomaterials has stimulated the biomedical sector to seek innovative alternatives to conventional medical technologies. Bio-optoelectronic devices are emerging as promising tools, integrating biologically derived components, biodegradable end-of-life approa...

Oxygen‐Tolerant, Controlled Synthesis of Degradable and Water‐Soluble Poly(Vinyl Amide)s via Radical Ring‐Opening Copolymerization of Cyclic Dithiothreitol

ABSTRACT Radical ring‐opening polymerization (rROP) has emerged as a powerful strategy for introducing degradable linkages into vinyl polymer backbones. In this study, we report an oxygen‐tolerant photoinduced electron/energy transfer reversible addition–fragmentation chain trans...

A survey on the institutional practices of the use of isavuconazole in onco-hematological children, on behalf of the Infectious Working Group of AIEOP

Isavuconazole is a broad-spectrum antifungal agent approved for the treatment of invasive fungal infections (IFIs) in adults and, recently, in pediatric patients aged 1 year and older. Use in the pediatric setting remains limited, but available data indicate generally favorable s...

Neuroradiological spectrum of sarcoma intracranial metastases: a single center study

Sarcomas are a heterogeneous group of rare tumors sharing a common origin from connective or other non-epithelial tissues. Although clinical case series of intracranial sarcoma metastases have already been published, their neuroradiological findings are poorly known. This study a...

A Scoping Review of Neurobiological and Brain Structural Alterations Following Child Exposure to Intimate Partner Violence

Intimate partner violence (IPV) is one global issue that can lead to neurobiological consequences and affect brain development across the lifetime. However, evidence is scattered across domains and age groups, making it difficult to map the breadth of empirical findings regarding...

Beyond optimisation: Revisiting energy demand management

Energy demand reduction (EDR) in households has re-emerged as a central pillar of climate and energy transition strategies in Europe and beyond. While energy efficiency has long dominated policy frameworks, growing evidence shows that efficiency alone is insufficient to achieve a...

The Flying Phase in Sprint Runners: Exploring Biomechanical Factors Associated With Performance

Abstract Faggian, S, Lei, LW, Ghezzo, E, Bucciol, M, Airale, M, Del Giudice, M, Breban, SG, Bozzato, M, Costa, I, Cutti, AG, Petrone, N, and Marcolin, G. The flying phase in sprint runners: Exploring biomechanical factors associated with performance. J Strength Cond Res XX(X): 00...

Sport, exercise, and physical activity in children with cardiovascular disease. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) of the ESC, the Association of Cardiovascular Nursing & Allied Professions (ACNAP) of the ESC, and the Association for European Paediatric and Congenital Cardiology (AEPC)

Regular physical activity offers numerous benefits to children's health and well-being and is essential for reducing cardiovascular risk in children with cardiovascular disease. Despite increasing evidence supporting its benefits, many young patients remain insufficiently active...

Effect Modification of Rescue Stenting in ICAS-Related Middle Cerebral Artery Occlusion: The Role of Thrombectomy Failure, Stenosis Severity, and ASPECTS

Rescue stenting (RS) is increasingly used for intracranial artery stenosis-related large vessel occlusion (ICAS-LVO), but optimal patient selection remains uncertain. We investigated the baseline and procedural factors associated with receiving RS and whether they modified the as...

Knowledge Improvement After a Neonatal Resuscitation Course in a Low-Resource Setting

Background: The application of neonatal guidelines developed for high-resource settings is often difficult in low-resource settings due to structural differences and lack of equipment and personnel. The Helping Babies Breathe (HBB) program has been developed to overcome this limi...

Vitamin D in coronary heart disease: a Mendelian randomization meta-analysis of data stratified by 25(OH)D levels

Maria Fusaro, Pasquale Perrone Filardi, Gianfranco Sinagra, Maria Luisa Brandi, Maurizio Gallieni, Jean-Yves Reginster, Eugene McCloskey, Etienne Cavalier,

A Dialogical Epistemology for Catholic Religious Education: Disciplinary Identity and Educational Openness in Plural Societies

Growing religious and cultural pluralism has placed dialogue at the centre of the international debate on Religious Education (RE). Contemporary scholarship has emphasised its importance for the study of religions, personal development, freedom of conscience, democratic citizensh...

The line, the strip and the duality defect

In the Symmetry Topological Field Theories (SymTFT) that describes the exotic models XY-plaquette and XYZ-cube, we construct codim-1 condensation defects by higher gauging with discrete torsion the non-compact symmetry of the bulk. In the framework of SymTFT Mille-feuille, which...

Beyond the class effect: Rethinking anticoagulation in liver disease

The use of direct oral anticoagulants (DOACs) has transformed hepatology. Initially introduced as an alternative to vitamin K antagonists and low-molecular-weight heparin for portal vein thrombosis (PVT), DOACs are now increasingly used across the spectrum of vascular liver disea...

The Behavior of the External Limiting Membrane and Ellipsoid Zone in Diabetic Macular Edema: A Population AI-Assisted Optical Coherence Tomography Study

Purpose: To investigate the behavior of the external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema (DME) using artificial intelligence (AI)-based optical coherence tomography (OCT) quantification. Methods: This was a cross-sectional study. OCT scans of...