University of Padua

Understanding the dynamics of decision-making in palliative care within collectivist contexts: integrative review

End-of-life decision-making in palliative care requires timely and compassionate communication to align care with patients’ goals and values. While shared decision-making is regarded as optimal for patient-centered care, its application in collectivist societies, where familial,...

The Sexual Allure of Intelligence: From Cognitive Intimacy to Erotic Desire - A Neuropsychological Theory of Epistemic Attraction

This conceptual article develops epistemic attraction as a provisional process construct for understanding how socially represented cognition can acquire sexual, romantic, and affective significance. Rather than treating sapiosexuality as a simple preference for intelligence, the...

UNet for automatic pneumothorax detection on canine and feline CTs

Abstract Pneumothorax is defined as the pathological presence of air or gas in the pleural space. This can be due to penetration of airthrough a pleuro-cutaneous, pleuro-pulmonary or pleuro-esophageal pathway. Pneumothorax is a potentially life-threateningcondition and its detect...

KDM6A loss enhances oxidative phosphorylation uncovering tissue-level convergent evolution

Abstract The tumor suppressor KDM6A / UTX , a histone demethylase and a 2-oxoglutarate-dependent dioxygenase, is frequently lost in many cancer types. We show that KDM6A loss pervasively activates oxidative phosphorylation in several solid tumors, generating a pseudo-hyperoxic en...

Updating the Prevalence of H. pylori and Extensive Precancerous Lesions in the Stomach: Results of a Multicenter, Endoscopic Study

Background/Objectives: H. pylori is the main preventable risk factor for gastric cancer through the development of extensive precancerous lesions, namely mucosal atrophy and intestinal metaplasia. Methods: This multicenter, nationwide study enrolled consecutive patients who under...

GRASP: a plant transformation-independent CRISPR-based system for affinity purification of specific chromatin loci

ABSTRACT Chromatin organization regulates genome stability and gene expression by controlling DNA accessibility to transcription factors and regulatory complexes. DNA-protein interactions are commonly investigated using chromatin immunoprecipitation (ChIP), which relies on specif...

Pediatric Arboviral Infections in Europe: Epidemiology, Clinical Features, Diagnosis and Prevention

Arboviral infections, including West Nile virus (WNV), dengue virus (DENV), chikungunya virus (CHIKV), Zika virus (ZIKV), and, to a lesser extent, Oropouche virus (OROV), pose a heterogeneous and evolving challenge for pediatric health in Europe. The increasing presence of compet...

Beyond mortality: behavioural disruption and reduced plasticity as sublethal effects of per- and polyfluoroalkyl substances

Abstract Environmental pollution represents a major global threat to biodiversity, interfering with a wide range of biological processes and functions. In recent years, behaviour has gained attention as a key focus for detecting the subtle adverse effects of pollution, as polluta...

Soft tissue sarcomas prognosis based on clinical-pathological profile: a retrospective population-based study

Soft tissue sarcomas (STSs) account for less than 1% of adult cancers and encompass a diverse range of neoplastic diseases. This population-based study evaluates the five-year overall survival rates of a cohort of STS patients. The study examined 325 incident cases of nonmetastat...

Aflibercept 8 mg for diabetic macular edema and neovascular age-related macular degeneration: an italian expert consensus paper

To provide consensus recommendations on the clinical use of aflibercept 8 mg in managing neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME) in the real-world setting. A modified Delphi study was undertaken, involving ophthalmologists from special...

Turning Failure into Success: Prosthetic Rehabilitation After Surgical Setback in Gingival Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is a common malignancy that can develop from precancerous conditions such as oral lichen planus (OLP). This case report describes the clinical management and complication reporting of a patient with OLP who developed an exophytic lesion on the...

Toward harmonized reporting of Alzheimer’s disease biomarkers in clinical practice

Abstract Cerebrospinal fluid biomarkers, and more recently blood-based biomarkers, are playing a pivotal role in reshaping the clinical management of neurodegenerative diseases, supporting early detection, biological diagnosis, patient stratification, prognostic assessment, thera...

Image-based estimation of ambient particulate matter: a scoping review

Abstract Air quality is a major public health concern, while particulate matter (PM) measurements remain limited by the spatial coverage and high operational costs of reference monitoring stations. This scoping review synthesises the literature on image-based PM estimation from o...

Severe Refractory Hypotension Following Patent Blue V Injection: A Case of Atypical Perioperative Anaphylaxis

Background and Clinical Significance: Patent Blue V (PBV) is widely used for sentinel lymph node mapping but may rarely cause severe hypersensitivity reactions. These reactions can present atypically, with predominant cardiovascular collapse and minimal cutaneous manifestations,...

Systemic reorganization of the photosynthetic apparatus underlies acclimation to nitrogen starvation across leaf ages in barley

Nitrogen (N) deficiency severely constrains global crop productivity, yet acclimation strategies in cereals remain incompletely understood. Hydroponically grown barley ( Hordeum vulgare ) plants were subjected to N starvation for 14 days. Photosynthetic properties were monitored...

Shape coexistence in 94Zr from a model-independent analysis

Low-lying states of 94Zr were investigated via low-energy multi-step Coulomb excitation. From the measured γ-ray yields, 16 reduced E2 transition probabilities between low-spin states were determined, together with the spectroscopic quadrupole moments of the 2+1,2 states. Based o...

Interpretable brain-age modeling reveals network-level reorganization in functional brain aging

Brain-age models based on functional connectivity have shown promise for characterizing large-scale age-related network changes and advancing understanding of neural aging mechanisms. However, existing approaches still face challenges in achieving both robust predictive performan...

Autochthonous chikungunya virus outbreak in Verona province, Italy, 2025

Abstract Background Chikungunya virus (CHIKV), primarily transmitted by Aedes mosquitoes, has increasingly caused autochthonous outbreaks in temperate regions, including Italy. In 2025, a local CHIKV outbreak occurred in Verona province, Veneto Region. We report the findings of i...

Estimating the Extent of Missed Opportunities for Osteoporosis Treatment Before Hip Fracture Occurrence

Abstract Hip fractures (HF) are among the most serious consequences of osteoporosis. Many individuals who subsequently sustain a HF may already fulfill recognized criteria for fracture risk assessment, bone mineral density (BMD) evaluation, or anti-osteoporosis treatment before t...

One vs twelve month aspirin after percutaneous coronary intervention for acute myocardial infarction: individual patient-data analysis of TARGET-FIRST and ULTIMATE-DAPT trials

Giuseppe Tarantini, Xiaojuan Zhang, Luca Nai Fovino, Jing Kan, Zhen Ge, Guillaume Cayla, Pieter C Smits, Benjamin Honton, Valeria Paradies, Yann Poezevara,