University of Padua

The Behavior of the External Limiting Membrane and Ellipsoid Zone in Diabetic Macular Edema: A Population AI-Assisted Optical Coherence Tomography Study

Purpose: To investigate the behavior of the external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema (DME) using artificial intelligence (AI)-based optical coherence tomography (OCT) quantification. Methods: This was a cross-sectional study. OCT scans of...

Delivering the EU Safe Hearts Plan: the essential role of laboratory medicine in cardiovascular health

Abstract The European Union Safe Hearts Plan provides an opportunity to strengthen cardiovascular prevention, early detection, treatment, and monitoring across Europe. This EFLM position paper argues that laboratory medicine must be recognized as a central component of its implem...

DARE to wear: digital health promotion and disease prevention using wearable devices

Global healthcare systems are under increasing strain to ensure long-term sustainability, necessitating a transition towards proactive, preventive healthcare strategies. Wearable sensor technologies are uniquely positioned to facilitate this paradigm shift by allowing continuous...

Revisiting the Normalization of the Moran's I Index: A Correlation‐Based Approach With Inference

Summary Moran's index, the canonical measure of spatial autocorrelation, may take values outside the interval when arbitrary spatial weight matrices are used. This lack of boundedness complicates interpretation and may lead to misleading conclusions. We systematically evaluate se...

Learning fuzzy normal-operation regimes for interpretable power system anomaly detection

This paper presents an interpretable one-class anomaly detection framework for power systems based on adaptive neuro-fuzzy inference systems (ANFIS). The proposed method is trained exclusively on benign operational data and learns a compact set of fuzzy regimes describing normal...

An Alternative Test to Evaluate the Assistance Provided by Back-Support Exoskeletons: A Pilot Study

OCCUPATIONAL APPLICATIONSThe test proposed in this study, assimilable to a maximal isometric mid-thigh pull, appears to detect the acute assistance provided by the exoskeleton, expressed as the difference in performance with and without donning the device; the test can be perform...

Challenge from nomenclature changes: the case of ascidian biodiversity

The stability of biological nomenclature is essential for estimating biodiversity and is ensured by the International Codes for Nomenclature. However, species names change over time due to advances in scientific knowledge and new technologies, such as DNA barcoding. While barcodi...

Regional signaling controls stem cell-mediated regeneration in an invertebrate chordate

Many tissues harbor quiescent stem cells that activate after injury, yet how local signals regulate this transition is not well understood. The solitary ascidian Ciona robusta provides a unique model, as bottom body fragments regenerate while upper fragments fail to do so. By com...

The Italian Nanomedicine Platform (INP): national integration within the European nanomedicine ecosystem

Italy’s nanomedicine expertise has long developed in fragmented manner, with limited coordination across academia, clinical institutions, industry and regulatory bodies. The Italian Nanomedicine Platform (INP) was established to integrate discovery, preclinical validation, regula...

A comprehensive assessment of dairy farming sustainability based on stakeholder priorities and concerns: a case study in Northern Italy

Improving the sustainability of dairy farming requires the identification of practices and indicators that are both scientifically robust and applicable under different farming conditions. This study aimed at identifying priority practices, perceived barriers and monitoring indic...

A cross-sectional study on illness perception and resiliency among cancer patients, in Bhaktapur cancer hospital

Cancer, characterized by uncontrollable abnormal cell growth, is one of the leading causes of death worldwide. According to the WHO, cancer accounted for nearly 1 in 6 deaths in 2020. Most research has focused on the physical well-being and quality of life of cancer patients. How...

Early Multicentre Outcomes of Endovascular Aortic Arch Repair Using a Custom-Made Triple-Branch NEXUS TRE Endograft System (TRE-ASURE Study)

Objective: To report the first multicentre European experience with the custom-made NEXUS TRE triple-branch endograft for fully endovascular, debranch-free repair of complex aortic arch pathology, focusing on technical feasibility and early safety outcomes. Methods: This retrospe...

Neural Interfaces for Bidirectional Sensory Restoration in Limb Prostheses: Current Evidence and Clinical Translation

Background: Restoration of sensory feedback has become one of the major goals of modern bidirectional neuroprosthetic rehabilitation, enabling the transition from conventional prosthetic replacement toward bidirectional neuroprosthetic systems capable of restoring physiological s...

In-Line Power Screwdrivers Recoil: A Pilot Computational Methodology to Assess Differences Among Workstations from a Human-Centric Perspective

Background/Objectives: Mechanical shocks generated by the recoil of hand-held power screwdrivers are a significant biomechanical stressor for the operator’s hand–arm complex. Currently, vibration exposure is measured at the tool-handle level, while operator-centered practical mea...

Transnationality as practice. An analytical proposal for applying Bourdieu in transnational studies

This article develops a praxeological approach to migrant transnationality drawing on Pierre Bourdieu’s theory. Based on qualitative research with Tunisian migrants and their descendants in Italy, it reconstructs the transnational social space of this community by identifying its...

Transverse Myelitis and Guillain–Barré Syndrome in Pediatric Lymphoid Malignancies: An International Retrospective Study

Central and peripheral neurotoxicity after methotrexate is a rare but challenging complication of therapy for pediatric lymphoid malignancies. In this Ponte-di-Legno Toxicity Working Group and international Berlin-Frankfurt-Münster Group study, we describe nine children and adole...

Ghettoising habitus, symbolic violence and migratory stratification: the experience of Italy’s Romani people

Analysing data collected by two studies on Italy’s Romani people, this article introduces the concept of ghettoising habitus. Building on Bourdieu, we show how the material segregation experienced by the Romani transformed into a symbolic disadvantage in various domains. Unlike o...

Optimizing LaNiO3 Perovskite as Catalyst Precursor for the Revalorization of Biogas by Dry Reforming of Methane

The Dry Reforming of Methane (DRM) is an efficient route to produce syngas (which is the feedstock for the production of synthetic fuels via the Fischer–Tropsch process) or hydrogen from methane and carbon dioxide. This work evaluates several nickel-based perovskite-type mixed ox...

Integrating Deep Neural Networks with Support Vector Machines for Gene Expression Classification

Gene expression classification remains a challenging task due to the high dimensionality and heterogeneity of available datasets. In this study, we present a comprehensive empirical analysis combining neural networks and Support Vector Machines (SVMs) for gene expression classifi...

4D printing modular twisting metamaterials with reprogrammable functionality and reconfigurable deformation

Developing torsional mechanical metamaterials capable of delivering reconfigurable and adaptive responses through compression-torsion coupling remains a significant challenge. Here, we present a bioinspired multifunctional twisting mechanical metamaterial (MTMM) featuring a modul...