University of Oslo

Carbon source-dependent metabolic states govern redox homeostasis and cofactor biosynthesis in Propionibacterium freudenreichii

ABSTRACT Microbial adaptation to fluctuating nutrient and oxygen conditions requires coordinated regulation of the metabolic network to maintain redox homeostasis within physicochemical and energetic constraints. While oxygen-dependent responses in Propionibacterium freudenreichi...

Attribution assignment for deep-generative sequence models enables interpretability analysis using positive-only data

Generative machine learning models offer a powerful framework for therapeutic design, by efficiently exploring large spaces of biological sequences enriched for desirable properties. Unlike supervised learning methods, which require both positive and negative labeled data, genera...

Major adverse cardiac events and mortality associated with ADHD and its treatment in adults with type 2 diabetes: a multi-national cohort study

Abstract Background Attention-deficit/hyperactivity disorder (ADHD) has been linked to elevated risk of type 2 diabetes (T2D). However, the impact of ADHD and ADHD medication use on prognosis and health outcomes in T2D remains unclear. This study investigates the associations of...

The Responsibility–Power–Justice Nexus: A Framework for Reorienting Behavioral Science Toward Power and Justice

Behavioral science has achieved remarkable policy influence, yet the problems it addresses, such as climate change, health inequality, and financial precarity, have worsened. We argue this is no coincidence. The field suffers from systematic power-blindness: it treats individuals...

More than just smiling: how positive emotions are expressed on the face

To advance the science of positive emotional expressions, we test how 22 positive emotions are spontaneously displayed on the face, using the participant-negotiated episodic recall method. Respondents (n = 163) narrated emotional events from their lives, and we extracted facial b...

Measurements of the production of W$$^{\pm }$$ and Z$$^0$$ bosons in pp collisions at $$\sqrt{s} = 13$$ TeV

Abstract Measurements of the production of the W $$^{\pm }$$ ± and Z $$^0$$ 0 bosons at midrapidity in pp collisions at $$\sqrt{s} = 13$$ s = 13 TeV with ALICE at the Large Hadron Collider (LHC) are presented. The W $$^{\pm }$$ ± and Z $$^0$$ 0 bosons are detected via their (di)e...

The Simons Observatory: Development of a Pipeline to Detect Rapid Transients in Time-Ordered Data

We introduce a method for detecting astrophysical transients evolving on timescales of milliseconds to minutes using cosmic microwave background (CMB) survey telescopes. While previous transient searches in CMB data operate in map space, our pipeline directly processes the raw ti...

Feasibility Study of an Ultra-Low-Cost 3D-Printed Wave Buoy for Water Wave Measurement

Abstract This paper presents a feasibility study of an ultra-low-cost wave buoy for measuring water waves, built from a 3D-printed hull and an off-the-shelf data logger with an integrated MEMS inertial measurement unit. The buoy records continuously and carries no telemetry, whic...

FREE ACTIONS OF POLYNOMIAL GROWTH LIE GROUPS AND CLASSIFIABLE C*-ALGEBRAS

Abstract We show that any free action of a connected Lie group of polynomial growth on a finite dimensional locally compact space has finite tube dimension. This is shown to imply that the associated crossed product C*-algebra has finite nuclear dimension. As an application we sh...

Waiting time and mortality after hip fracture: findings from a large single-center cohort study

Time to surgery after hip fracture is a potentially modifiable factor that may influence mortality, but the evidence for an association is conflicting for waiting time < 48 h. The aim of this study was to investigate the association between waiting time to surgery and mortality,...

Seasonal influences on DNA methylation at birth or at sampling time and their interaction with psychosis risk

Abstract Background Season at birth has been associated with increased risk for psychotic disorders. Epigenetic markers, which can be influenced by environmental exposures, may help to understand the mechanisms of seasonal effects. Aims To investigate two types of seasonal influe...

An integrated spatially defined roadmap of normal and cancer-associated colon fibroblasts

Abstract Cancer-associated fibroblasts (CAFs) promote tumorigenesis and represent potential therapeutic targets, highlighting the need for precise understanding of CAF heterogeneity. In colorectal cancer (CRC), CAF subsets and nomenclature vary widely, and many studies overlook t...

Bounds on the determinant of an exponential matrix

Abstract We derive upper and lower bounds on the determinant of an exponential matrix. They can be transformed into corresponding bounds for the determinant of a univariate Gaussian matrix.

Electric imperialism: Europe, state capital and the global political economy of the energy transition

Foregrounding the growing prominence of European state-owned electric utilities (electricity SOEs) in renewable energy generation, this article sets out to advance a new understanding of the ‘green capitalist state’ and its role in shaping the uneven geographical development of t...

Porphyrin-Cross-Linked Unimolecular Polyglycerol Nanogels: Confinement-Controlled Metalation and Selective Cu2+ Detection

Abstract Unimolecular nanogels (NGs) based on (hyper)branched cyclic polyglycerols ((h)bcPGs) of two molecular weights (Mn = 8 and 60 kDa) were prepared through intramolecular cross-linking with the tetraboronic acid–functionalized porphyrin, 5,10,15,20-(tetra-4-dihydroxyborylphe...

Transcribathon. Building a Sustainable Community of Practice around Historical Transcription and Handwritten Text Recognition

Abstract As the library at Norway’s oldest and largest university, we support research partnerships with academic staff, students, and faculty daily. Increasingly, we receive requests from researchers across disciplines for assistance with transcribing written historical document...

Transcribathon. Building a Sustainable Community of Practice around Historical Transcription and Handwritten Text Recognition

Abstract As the library at Norway’s oldest and largest university, we support research partnerships with academic staff, students, and faculty daily. Increasingly, we receive requests from researchers across disciplines for assistance with transcribing written historical document...

Global policy determinants of national human papillomavirus vaccine introductions in 2006–2025

BACKGROUND: Although safe and effective human papillomavirus (HPV) vaccines have been available since 2006, national introduction in low- and middle-income countries (LMICs) has progressed slowly. HPV vaccine adoption may have been shaped by evolving World Health Organization (WH...

A GENETIC APPROACH TO UNDERSTANDING PSYCHOTROPIC DRUG EFFECTS ON BRAIN STRUCTURE

While neuroimaging studies have reported many brain alterations linked to psychiatric disorders, there has been substantial heterogeneity in findings. Effects of psychotropic medications on brain structure likely contribute to this inconsistency, yet disentangling disorder from d...

Genome-wide analysis of social behaviour across social domains, reporters and developmental stages: a meta-regression approach

Abstract Social behaviour is a heritable trait linked to well-being and mental health, yet it varies across social context, including social domains, informants and development, which may shape its underlying genomic architecture. Here, we conducted a genome-wide meta-regression...