University of Minnesota

Training investment indicators beyond cost: analyzing the impact of training on organizational outcomes

Organizations invest heavily in employee training, yet firms and firm-level research typically evaluate that investment by cost alone. Cost, however, reveals little about how training is delivered, how widely it reaches employees, or whether the firm has the resources to translat...

Exploring the Mutual Effects of Excipients and Proteins in Complex Coacervation

Abstract Complex coacervation is a type of associative liquid−liquid phase separation driven by the electrostatic complexation of oppositely-charged macromolecules. Coacervate materials have shown significant potential for the formulation of proteins and viruses with improved the...

Intellectual Humility Promotes Balanced and Integrated Understandings of Controversial Information in Multiple Documents

This study examined associations between individual differences and construction of mental representations of belief-consistent and belief-inconsistent claims. Individual differences included topic beliefs, confidence in belief accuracy, and interest, and the focal construct (int...

SN 2024iss: A Multiwavelength Exposé of a Type IIb Supernova with an Early-time Ultraviolet Spectrum and Shock-breakout Constraints

Abstract We present multiwavelength observations and analysis of SN 2024iss, a Type IIb supernova (SN IIb) located at ∼14 Mpc. The first Zwicky Transient Facility detection of SN 2024iss is ∼40 minutes after first light (one of the earliest detections of a SN IIb to date) and a H...

Beyond nation-state rhetoric: exploring the transnational mobility narratives of Vietnamese international undergraduate students in the US

Abstract This paper examines how Vietnamese international undergraduate seniors in the US make sense of their trajectories abroad and, in doing so, challenge the dominant discourses on international education in US-Vietnam relations. While the US frames international students as...

Foliar metabolomes of woody plant communities across an elevational gradient on Mount Washington (New Hampshire, USA)

Abstract Background and Aims Plants produce myriad specialized metabolites that constitute the metabolome and mediate responses to abiotic and biotic factors. Elevational gradients, where environmental conditions change predictably over short distances, are natural laboratories f...

Targeting pancreatic cancer with adenoviral vectors equipped with transgenes

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, and current therapeutics provide limited benefits to patients. Desmoplasia and the highly immunosuppressive tumor microenvironment (TME) play a huge role in PDAC being elusive to current therapeutics. Here...

LLMs in Wikipedia: Investigating How LLMs Impact Participation in Knowledge Communities

Large language models (LLMs) are reshaping knowledge production as community members increasingly incorporate them into their contribution workflows. At the same time, participating in knowledge communities involves more than just contributing content - it is also a deeply social...

Second‐Sphere Aromatic Substitutions That Tune H‐Atom Transfer Reactivity Observed for a Series of S = 1 Nonheme Fe IV =O Complexes: An Enthalpy‐Entropy Compensation Effect

ABSTRACT Synthetic nonheme Fe IV ═O complexes reported thus far often have S = 1 ground states, demonstrating markedly lower oxidative reactivity in C─H bond breakage compared to their S = 2 counterparts. Recently, we have identified that incorporating cycloalkyl groups into the...

Compartmental-Reaction Diffusion Framework for Microscale Dynamics of Extracellular Serotonin in Brain Tissue

Abstract. The neurotransmitter serotonin (5-hydroxytryptamine) shapes the plasticity and integration of network dynamics in the entire brain. In contrast to axons that have well-defined targets and form classical synapses, serotonin-releasing (serotonergic) axons often produce ra...

Unique challenges, unique solutions: end-user designed strategies to improve PTSD treatment initiation in U.S. Special Operations Forces

Abstract Background Despite the effectiveness of evidence-based psychotherapies for posttraumatic stress disorder (PTSD), uptake of treatment remains particularly challenging for some subgroups at high risk for PTSD. United States (U.S.) Special Operations Forces (SOF) Operators/...

AI Quality and Clinical Roles Impact Decision Quality in AI-Augmented Medical Decisions More than AI Explanations

BACKGROUND: Explainable AI has garnered significant attention in recent years, particularly in high-risk domains such as health care. Despite the enthusiasm, empirical evidence on the impact of AI explanations remains mixed. This study explores the effects of AI-generated recomme...

Reliability of computational versus noncomputational metrics of working memory and episodic memory in serious mental illness.

= 76). These participants were tested in working memory and episodic memory paradigms. We applied a computational model that yielded parameters corresponding to memory storage capacity, memory precision, and the rate of attention lapses. We also examined a noncomputational metric...

Hospitalisation in cirrhosis is linked to distinct gut microbiome structural and functional profiles: a multinational metagenomic study

Background Hospitalisations represent major clinical events in cirrhosis, yet prediction based on clinical variables alone remains limited. Objective Given the role of the gut microbiome in disease progression, we evaluated whether gut metagenomic profiles are associated with 90-...

Algebraic Localization Implies Exponential Localization in Non-periodic Insulators

Abstract Exponentially-localized Wannier functions are a basis of the Fermi projection of a Hamiltonian consisting of functions which decay exponentially fast in space. In two and three spatial dimensions, it is well understood for periodic insulators that exponentially-localized...

Bridging the data latency gap: automated extraction of genomic biomarkers from unstructured clinical documents to support real-world oncology data

Abstract Purpose Real-world oncology data are essential for clinical research and precision cancer care. However, genomic biomarkers are often embedded in scanned, unstructured clinical documents requiring manual abstraction before becoming available in cancer registries, delayin...

Five-expert PDE: lean formalization

Lean formalization for the explicit solution of the 5-expert PDE.

Terrestrial paleoenvironments and paleoclimate during the Miocene climate optimum at Buluk, East Turkana, Kenya

Understanding the environmental and climatic context of Neogene fossil localities in eastern Africa is critical for determining potential drivers of evolution in our hominoid ancestors and their floral and faunal communities. In this study, we reconstructed paleoenvironments and...

Framing Homelessness as a Public Health Emergency: Dominant Narratives & Policy Implications in Minneapolis Local TV News

Abstract Homelessness reflects a housing system in crisis, a profound public health challenge, and a manifestation of structural racism that has produced stark racial disparities in exposure to homelessness. While framing homelessness as a public health issue may highlight struct...

Ventricular Fibrillation Mapping in a Large-Animal Model Using Dual Mechanical Circulatory Support: Electroanatomic Substrate Preservation Without Ischemic Changes

BACKGROUND: Ventricular fibrillation (VF) remains a leading cause of sudden cardiac death with an incompletely characterized electrophysiological substrate. Traditional large-animal VF models are limited by hemodynamic collapse and myocardial ischemia. This study establishes a re...