University of Manitoba

Tibial migration of a novel cementless total knee arthroplasty

Aims The search for enhanced fixation and longevity in total knee arthroplasty (TKA) continues. Radiostereometric analysis (RSA) allows early detection of implant migration predictive of future aseptic loosening and is the recommended method for evaluating new implants. This mult...

From Awareness to Action: Co‐Designing Culturally Safe and Equitable Rehabilitation in Canada – Protocol for the Two‐Phase Ireach Qualitative Study

ABSTRACT Background Inequities in access, engagement, and outcomes persist across outpatient rehabilitation services in Canada, disproportionately affecting Indigenous Peoples, newcomers and refugees, gender‐ and sexually‐diverse individuals, and people with lower income. Althoug...

NORAD and USNORTHCOM revisited: or what I learned from Joel Sokolsky

Joel Sokolsky's scholarship profoundly shaped how generations of students and scholars understood North American defence, particularly the evolving relationship between Canada, the United States, NORAD, and USNORTHCOM. Inspired by his insights, this paper revisits a question Soko...

Antibiotic-resistant Acinetobacter calcoaceticus-baumannii complex in the environment: a narrative review

Abstract Acinetobacter calcoaceticus–baumannii complex comprises of both environmental and pathogenic bacterial species. Pathogenic species are responsible for nosocomial infections, which are increasingly difficult to treat due to growing resistance to antibiotics. In addition t...

A scoping review of positive youth development coach education programmes: implications for future research

Many positive youth development-focused coach education programmes (PYD-focused CEPs) have been designed to help coaches learn the processes and mechanisms associated with fostering life skills and values, amongst other PYD outcomes. Previous reviews of PYD through sport have foc...

Acceptability of My Ten: a physical activity intervention for family caregivers of people with advanced cancer

Abstract Background The caregiving experience can have a significant impact on family caregivers’ (caregivers) health and well-being, particularly those of patients with advanced cancer. Interventions to support caregivers through health-promoting strategies are needed. The physi...

The Impact of Corporate Governance on Corporate Performance – A Study of Technological Companies on the FTSE 250 London Stock Exchange

The significance of effective corporate governance cannot be overemphasized, since it directly affects the entire functioning of a firm. Corporate governance is a brand theory concerned with the alignment of management and shareholder interests. This study examined the impact of...

The Impact of Undiagnosed Child ADHD on Family Outcomes

Objective This study examined the relationship between child attention-deficit/hyperactivity disorder (ADHD) diagnosis and family outcomes (i.e., parenting stress, coparenting relationship quality, and family quality of life). Background While previous research has studied the ef...

Effects of Renin–Angiotensin Inhibitors, Sodium–Glucose Cotransporter 2 Inhibitors, Mineralocorticoid Receptor Antagonists and Glucagon‐Like Peptide 1 Receptor Agonists on Kidney Outcomes in Patients With Type 1 Diabetes: A Systematic Review and Meta‐Analysis

ABSTRACT Aims While the new kidney protective therapies have transformed chronic kidney disease (CKD) management in patients with Type 2 diabetes mellitus (T2DM), treatment options for CKD in Type 1 diabetes mellitus (T1DM) have remained unchanged for 30 years, limited to renin–a...

Balancing data quality and participant burden: a comparative analysis of abbreviated vs extended symptom diaries in the CanTreatCOVID trial

Abstract Background Symptom diaries are widely used in acute respiratory infection trials to capture patient-reported symptom severity and recovery. Longer questionnaires may provide a more complete clinical picture but can increase participant burden and reduce adherence. Eviden...

Theory–simulation–application framework to enhance biostatistical capacity for HIV and cancer data analysis in sub-Saharan Africa: lessons learnt from Tanzania

Enhancing biostatistical capacity in sub-Saharan Africa (SSA) is imperative for the efficient analysis of routinely collected health data and for clinical and public health decision-making. We describe the experiences and lessons learnt from implementing advanced statistical capa...

Tree-based structural equation model for assessing measurement invariance in patient-reported outcome measures

Evidence of measurement invariance (MI) is essential to ensure that scores based on patient-reported outcome measures (PROMs) are comparable across groups or over time. Conventional methods for evaluating MI in PROMs are mostly group-based methods that require that relevant diffe...

European Association of Palliative Care White Paper on research priorities for family caregiving in palliative care: A systematic review of reviews

BACKGROUND: Family carers are central to providing high quality palliative care. However, gaps remain in our understanding of how best to support carers. In 2010, the European Association for Palliative Care published a White Paper on 'Improving Support for Family Caregivers'. Th...

Comparative Effectiveness of Surgical and Non-Surgical Management of Pediatric Femoral Shaft Fractures: MetaAnalysis of Radiological Outcomes and Complications

ABSTRACT: Pediatric femoral shaft fractures can be managed using both surgical and non-surgical strategies, with treatment selection influenced by age, body weight, fracture stability, and associated injuries. This systematic review and meta-analysis aim to compare radiological,...

Food-Derived l -tryptophan and α-Casein (90–95) Differentially Potentiate Porcine Calcium-Sensing Receptor Signaling and Improve Enteroendocrine–Epithelial Responses Under Peptidoglycan Challenge

Abstract The calcium-sensing receptor (CaSR) is a nutrient-sensing class C G protein-coupled receptor implicated in intestinal hormone release, yet the signaling pharmacology of the porcine receptor and its relevance to epithelial homeostasis remain poorly defined. Here, a stable...

Comparative Effectiveness of Surgical and Non-Surgical Management of Pediatric Femoral Shaft Fractures: MetaAnalysis of Radiological Outcomes and Complications

ABSTRACT: Pediatric femoral shaft fractures can be managed using both surgical and non-surgical strategies, with treatment selection influenced by age, body weight, fracture stability, and associated injuries. This systematic review and meta-analysis aim to compare radiological,...

Religious Affiliation and Reported Dual Menstrual Material Use Among Young Women in India

Background: Dual-method menstrual hygiene use, defined as the use of both modern menstrual hygiene products (e.g., sanitary pads) and traditional materials (e.g., cloth), remains under-researched among young women in India. While socioeconomic factors are associated with menstrua...

Ebola Virus RNA Persists in Reproductive Tissues and Sperm of Male Ifnar1−/− Mice After Resolution of Viremia

Ebola virus (EBOV) has been shown to persist in the reproductive tracts of male Ebola virus disease (EVD) survivors ranging from months to years following recovery, with shedding of EBOV in semen leading to chains of disease transmission. In the current study, we used a mouse mod...

Diabetes and Driving: How Predictive Technologies Will Alter Ethical and Legal Responsibilities

In 2023, a 67-year-old man with long-standing type 1 diabetes experienced a severe hypoglycemic episode and drove into an outdoor dining area in Victoria, Australia, killing 5 people and injuring several others. Although the charges against the driver were dismissed, future cases...

Transforming Science with Large Language Models: A Survey on AI-assisted Scientific Discovery, Experimentation, Content Generation, and Evaluation

With the advent of large multimodal language models, science is now at a threshold of an AI-based technological transformation. An emerging ecosystem of models and tools aims to support researchers throughout the scientific lifecycle, including (1) searching for relevant literatu...