University of California, Irvine

Trends in Spending on Corrective Lenses

Importance About 50% of the population has a refractive error, but corrective lenses can impose cost barriers on patients given the lack of widespread vision insurance. Objective To describe temporal trends and sociodemographic variation in corrective lens spending and payment so...

Self-starter or sidekick? Independent and spillover effects of Opportunity Zones on housing supply in cities

The Opportunity Zone (OZ) program, created under the 2017 Tax Cuts and Jobs Act, offers capital gains tax incentives to encourage investment in low-income communities. While proponents argue the program catalyzes new development, critics contend it may subsidize projects that wou...

A genetic algorithm–optimized EWMA control chart integrating machine learning-based risk prediction for multistage thyroid cancer treatment monitoring

Effective monitoring of thyroid cancer treatment requires timely detection of clinically meaningful changes across complex, multistage care pathways. Traditional monitoring approaches often rely on static thresholds and periodic assessments, limiting their sensitivity to subtle y...

Anthropogenic aerosol reduction contributes to faster flash drought onset in a changing climate

Flash droughts have emerged as severe hazards, posing growing challenges to natural and socioeconomic systems, yet the influence of recent aerosol reductions on their onset remains unclear. Here, we investigate the impacts of aerosols and their underlying mechanisms using multi-s...

Investigating Buoyant Plume Dynamics Induced by Localized Fire‐Simulated Heating Over Plant Canopies Using LES

Abstract Plume interaction with a forest canopy results in flow features distinct from those in grasslands. Here, we model the turbulence dynamics of a buoyant plume in a homogeneous plant canopy with a crosswind using Large‐Eddy Simulations. As the plume interacts with the cross...

Emergency Department Visits After Heightened Immigration Enforcement in Los Angeles County

This cross-sectional study examines whether an increase in immigration enforcement activity in Los Angeles County during June 2025 was associated with changes in emergency department and inpatient utilization by patient country of birth.

A Multi-Institutional Digital Twin and AI Educational Platform for Advanced Microelectronics Fabrication and Device Packaging Training

Technology today is at a crossroad between Industry 4.0 and 5.0, where products and services are manufactured and designed to be ‘human-centered’ and sustainable. Such objectives have always been expected in education, especially in the way the workforce is trained. Leveraging on...

Stress, Support, and Resilience During Wartime: A Dyadic Longitudinal Study of Parental Exhaustion

ABSTRACT Objective This study aimed to broaden the understanding of how parental exhaustion evolves during war, and how war exposure and social support are associated with these changes within individuals and between partners. Background Wars exert strain on parents. The Balance...

Breaking the Code: Creating Engaging Lock-Based Activities to Transform Student Learning Experiences

Abstract General Chemistry serves as a foundational course for STEM students, where early engagement and confidence are critical to academic success. To reinforce core concepts from college-level introductory chemistry courses, we developed an interactive puzzle box game focused...

Deterministic Fully-Static Whole-Binary Translation without Heuristics

We present Elevator , the first binary translator capable of statically translating entire x86-64 binary executables to AArch64 without using debug information, source code, or any assumptions about code patterns or layouts within the original binary. Unlike existing binary trans...

D-allose reprogrammes the mitophagy–mtDNA–cGAS–STING–ADM2 axis to restore nucleus pulposus cell homeostasis in intervertebral disc degeneration

Intervertebral disc degeneration (IVDD) is driven by progressive loss of nucleus pulposus cell (NPC) homeostasis, yet the stress-responsive mechanisms governing this process remain incompletely defined. Here, we identify a mitochondrial stress-innate immune signalling axis in whi...

Superoxide Release from Macrophages upon Exposure to Secondary Organic Aerosols, Biomass, and Plastic Burning Particulate Matter

Abstract Oxidative stress induced by reactive oxygen species (ROS) is a key process for adverse health effects upon respiratory deposition of particulate matter (PM). Alveolar macrophages can release superoxide upon phagocytosis of PM through a process called the respiratory burs...

Reading Incivility Through Camp: Moral Binaries in Nursing Education.

In the United States context, incivility in nursing education is widely studied as a behavioral problem to be measured and remedied. In contrast, civility has been conceptualized as a professional virtue that is foundational to nursing identity. Together, these civility and inciv...

Towards Explorative IRBL: Combining Semantic Retrieval with LLM-Driven Iterative Code Exploration

Information Retrieval-based Bug Localization (IRBL) aims to identify buggy source files for a given bug report. Traditional and deep learning-based IRBL techniques often suffer from vocabulary mismatch and dependence on project-specific metadata. In contrast, recent Large Languag...

Evaluating Glanceable Multi-Device Family Health Tracking with Smartwatches and Home Displays

While ubiquitous computing research has explored diverse devices for personal health tracking, we know less about multi-device designs for family informatics, where health management is inherently collaborative. To understand how families adopt and perceive ubiquitous access to s...

Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in a multiethnic US population

Abstract Neuroinflammation is associated with depression and anxiety risk, both of which demonstrate a bilateral relationship with cardiometabolic disorders. Systemic inflammation was also commonly described in patients with cardiometabolic disorders. It is, thus, unclear whether...

Entangled photon pair excitation and time-frequency-filtered multidimensional photon correlation spectroscopy as a probe for dissipative exciton kinetics

In quantum aggregates, delocalized exciton states across energy manifolds interact with phonon modes, making state-resolved spectroscopic monitoring of dynamics challenging. We propose a scheme that combines photon-entanglement-enhanced narrowband excitation of two-exciton states...

Unusual Presentations of Uterine Rupture: A Case Series

Uterine rupture is an uncommon, but serious intrapartum complication. It is most often seen in patients with a prior low-transverse cesarean delivery undergoing a trial of labor (TOLAC). In our experience, not all ruptures present in patients with clear risk factors or with the c...

Generative AI‐Enabled Discovery and Experimental Demonstration of Ultra‐Broadband Epsilon‐Near‐Zero Perfect Absorbers

ABSTRACT Artificial intelligence is reshaping the discovery and engineering of photonic materials. Here, we introduce a data‐driven framework that employs a generative deep neural network to create ultrathin, multilayer epsilon‐near‐zero absorbers with record‐breaking broadband p...

Estimating VO 2 max With the Timed Mile Run: An Updated Equation for Today's Youth

ABSTRACT Background School‐based physical fitness testing (SB‐PFT) is an important tool to address youth physical inactivity. However, the widely used Fitnessgram equation that converts timed mile run performance into estimates of cardiorespiratory fitness (VO 2 max) may not be v...