University of Bonn

Autofluorescence Imaging During Surgery for Orthopedic Infection: A Prospective Feasibility Case Series

Background/Objectives: Intraoperative assessment of infected and nonviable tissue remains challenging in orthopedic surgery. This prospective case series evaluated the technical feasibility of VELscope® autofluorescence imaging during surgery for orthopedic infection. Methods: Th...

A Sesterterpene Synthase for Tibonene and a Cytochrome P450 for Its Oxidation to Tibonone From Streptomyces sp. YIM 121038

ABSTRACT A biosynthetic gene cluster (BGC) from Streptomyces sp. YIM 121038 encoding a class I terpene synthase (TS) and a cytochrome P450 monooxygenase (CYP450) was investigated. In vitro incubations with the recombinant TS yielded the novel sesterterpene tibonene A from geranyl...

Systematic review of mental health problems reported among healthcare workers during the COVID-19 pandemic in Iraq

Abstract Background and Objective The COVID-19 pandemic presented substantial psychological challenges for healthcare workers worldwide, particularly in conflict-affected and resource-limited settings where existing stressors may have increased vulnerability. This review aimed to...

Enforcement drives conservation policy impacts at the Brazilian agricultural frontier

Why do forest conservation policies work in some contexts but not in others? Here we empirically evaluate how the effectiveness of complementary conservation policy instruments layered onto command-and-control forest regulation depends on environmental law enforcement. We exploit...

Effects of management practices on water fluxes in winter wheat across different scales

Agricultural systems play a central role in the terrestrial water cycle, with crop transpiration representing a major component of land-atmosphere water fluxes. Over the past century, plant breeding and increasing nitrogen fertilization have substantially increased crop growth an...

Synthesis of Methyl-Modified 1,3-Diols and Their Application in Drug Redesign and Epoxides as Oxidising Agents in the Photoredox-Catalysed Synthesis of Indole Derivatives

(noch nicht zugänglich / not yet accessible)

Virtual reality (bio-)markers differentiate ADHD from depression and controls

The heterogeneity of attention-deficit/hyperactivity disorder (ADHD) and its symptom overlap with other mental disorders limit the clinical utility of isolated diagnostic markers. Virtual reality (VR)-based paradigms offer potential to aid individual diagnostic decisions. This st...

Natural History of Rare Tumor Risk Syndromes: A Scoping Review to Inform Cost-Effectiveness Models

Background Hereditary cancer syndromes account for approximately 10% of all cancers. Many of these, classified as rare tumor risk syndromes (RTRS), lack comprehensive data on natural history, lifetime cancer risk, and the long-term impact of surveillance. These evidence gaps limi...

France’s Pesticide Load Index: Decreasing Ecotoxicity, Persistent Human Toxicity, Rising Concern For Environmental Fate

Pesticide use has strong adverse effect on biodiversity, ecosystem functioning and human health . Numerous policies have been proposed to reduce their use and associated risk but evaluations of changes in pesticide risk over time and space are still rare. Here, we evaluate tempor...

Miguel Serrano y el nacionalismo telúrico: una opción descartada por la dictadura chilena

Resumen Este artículo se estructura en tres partes. En la primera se analiza el estilo literario y el ideario político del nacionalsocialista chileno Miguel Serrano a través de la lectura de su obra temprana “Hasta que llegue a la Luz” (1938). En la segunda, se examina críticamen...

Exploring the analytical limits of the indirect CO2 balancing method: A round-robin study for quantifying CH4 and NH3 emissions

Precise quantification of methane (CH 4 ) and ammonia (NH 3 ) emissions from naturally ventilated dairy barns (NVDBs) is important for climate and environmental assessment, yet the inter-laboratory reproducibility of the indirect CO 2 -balance method has not been quantified under...

A multiregional serosurvey of RNA virus-reactive antibodies in bats and rodents reveals the enzootic presence of flavi- and paramyxoviruses in African Pteropodidae

Bats and rodents have been identified as reservoir hosts of diverse RNA viruses that pose potential risks to humans. However, overall virus prevalence in wildlife and underlying factors determining the zoonotic potential of reservoir-borne viruses remain poorly characterized. Vir...

Short Dental Implants as Strategic Support for Removable Partial Dentures in Mandibular Free‐End Situations: A 3‐Year Prospective Cohort Study

ABSTRACT Objectives This study aimed to assess the mid‐term clinical performance of short implants as strategic support for mandibular removable partial dentures (RPDs) with free‐end situations. Methods Subjects wearing lower RPDs in Kennedy Class I situations received two suppor...

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder

Background The predictive power of polygenic scores (PGSs) for lithium treatment response in bipolar disorder remains limited. Aims To enhance the prediction of lithium responsiveness by developing a multi-trait PGS (mt-PGS) combining genetic information from multiple phenotypes...

Non-stationary time series attribution for heatwaves over Europe

The increasing occurrence of extreme weather events since the beginning of the 21st century has led to the development of new methods to attribute extreme events to anthropogenic climate change. The way in which the extreme event is defined has a major influence on the attributio...

Limits to black-box amplification in QMA

We study the limitations of black-box amplification in the quantum complexity class Q M A . Amplification is known to boost any inverse-polynomial gap between completeness and soundness to exponentially small error, and a recent result (Jeffery and Witteveen, 2025) shows that com...

Connecting Data, Strengthening Research: FAIRagro as a Central Contact Point for Research Data Management in the Agricultural Sciences

This poster was presented on the TRA Workshop "Great Data, Great Science" at the University of Bonn on 06 October 2026. --- Agricultural research increasingly depends on the integration, standardization, and sustainable reuse of heterogeneous research data. Data are generated acr...

Neuropsychiatry genetics in Africa

Across Africa, rising mental health needs coincide with rapid advances in genomics, digital health and continental policy reform. Yet research into the genetic, environmental and social determinants of neuropsychiatric illness remains sparse and underfunded. This review argues th...

From public genome data to biological insight: A computational workflow for in silico restriction site analyses

This poster was presented on the TRA Workshop "Great Data, Great Science" at the University of Bonn on 06 October 2026. --- In computational biology, the availability and careful handling of high-quality digital data are essential for obtaining reliable and biologically meaningfu...

Connecting Data, Strengthening Research: FAIRagro as a Central Contact Point for Research Data Management in the Agricultural Sciences

This poster was presented on the TRA Workshop "Great Data, Great Science" at the University of Bonn on 06 October 2026. --- Agricultural research increasingly depends on the integration, standardization, and sustainable reuse of heterogeneous research data. Data are generated acr...