University of Basel

Integrating human rabies vaccines into routine immunization services in Tanzania: A participatory systems mapping study

Abstract Study aim : Human rabies is 100% preventable with post-exposure prophylaxis (PEP) administered immediately after exposure to a rabid animal. In low-income countries, access to PEP is hampered by challenges, including frequent vaccine stockouts, limited facilities providi...

Exit, voice, and adaptive livelihood diversification: Reframing coffee abandonment as transformative climate adaptation in East Africa

Climate change adaptation discourse has a habit of casting smallholder farmers as passive recipients of interventions designed to keep them producing for global market demand. This framing obscures both farmer agency and the power relations embedded in sustainability governance....

Introducing the Peace Observatory: Peace Negotiations and Mediation in Armed Conflicts

This article introduces the Peace Observatory, a new global dataset that captures over 10,000 rounds of peace negotiations in interstate, intrastate, and non-state conflicts between 1989 and 2023 with regular updates planned for additional years. The Peace Observatory disaggregat...

One Health epidemiology of cystic echinococcosis in Bhutan: A hospital-based study with complementary abattoir surveillance data

Abstract Background : Cystic echinococcosis (CE) is a neglected zoonosis that disproportionately affects rural and economically disadvantaged populations worldwide. Although CE cases have been reported in Bhutan, epidemiology of CE remains unclear, and evidence integrating human...

Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression

Abstract Prenatal maternal depression may have intergenerational effects on offspring brain development, with potential socioemotional consequences. This observational follow-up study examines brain development and subsequent negative emotionality among 109 infants born to mother...

Perspective: Quantum Computing on Magnetic Racetrack

ABSTRACT Magnetic domain walls have long been pursued as carriers of classical information for storage and processing. With the ability to create, control, and probe domain walls at the nanoscale, they are recently recognized as an ideal platform for studying macroscopic quantum...

Protocol for a cluster randomized controlled trial among young people and their peers to reduce substance use and inequitable gender beliefs in Southern Africa

BACKGROUND AND AIMS: Substance use and the internalization of traditional gender norms, or inequitable gender beliefs, are co-occurring risk behaviors for poorer health and well-being in young people in Southern Africa. Addressing the social and structural factors that reinforce...

Predicting Climate Adaptation Intention and Collective Climate Action

Abstract: Individual adaptation to climate hazards (e.g., create an emergency plan) and collective climate action (e.g., participate in a protest) arises from the interplay of numerous variables. Traditional linear models often fail to capture this complexity. This study employed...

Synoptic and regional-scale meteorological controls of stratus altitude in the Namib Desert

Abstract. In the Namib Desert, fog is an essential water source and occurs when and where advected marine stratus clouds intersect with the land surface. However, the meteorological controls of the cloud base height are still insufficiently understood. This study aims to develop...

Longitudinal Functional Magnetic Resonance Imaging to Assess Lung Disease in Cystic Fibrosis

Abstract Rationale Matrix pencil decomposition magnetic resonance imaging (MP-MRI) enables quantitative assessment of lung ventilation and perfusion and was shown to correlate with contrast-enhanced (CE) perfusion MRI. Objectives To determine the longitudinal course of MP-MRI par...

Cardiac Myosin‐Binding Protein C for Diagnosis of Myocardial Infarction in Patients With Prior Coronary Artery Bypass Grafting

Background Diagnosing myocardial infarction in patients with prior coronary artery bypass grafting (CABG) remains challenging, primarily because of lower diagnostic accuracy of high‐sensitivity cardiac troponin (hs‐cTn). cMyC (cardiac myosin‐binding protein C), because of its fas...

The relationship between evolvability and plasticity under experimental warming across species’ elevational ranges

Phenotypic variation among individuals of a population arises from genetic and environmental effects. These may be correlated if they have similar underlying developmental mechanisms or selection histories. We tested empirically for such links over elevation gradients, on which s...

Die vergangene Zukunft der Literaturtheorie. Zur temporalen Dimension disziplinärer Arbeitsteilungen

Abstract The essay departs from the so-called »end of theory« and relates it to transformations of temporal horizons: the loss of an emphatic conception of the future, ecological crises, and artificial intelligence. It engages in conversation with two developments, each starting...

Produktive Fehlinterpretation. Zu drei Reflexionsfiguren in Jurij M. Lotmans Die Innenwelt des Denkens

Abstract The article examines Jurij M. Lotman’s Universe of the Mind from the perspective of productive misinterpretation. Proceeding from the observation that misunderstanding, incomplete translation, and communicative disruption are conceptualised by Lotman not as deficiencies...

Th2/Th17 Inflammation: Pathogenic Drivers and Therapeutic Targets in Darier and Hailey‐Hailey Diseases

ABSTRACT Background The inherited acantholytic dermatoses Darier disease (DD) and Hailey‐Hailey disease (HHD) are characterized by a barrier dysfunction of the epidermis susceptible to inflammation and microbial infections. Objectives This study aimed at investigating the express...

European joint programme HBM4EU - Bridging science and policy: experiences and lessons learned from the key partners in the scientific steering of the initiative

The European Joint Programme HBM4EU was established to address politically relevant questions on chemical risks to public health through a targeted human biomonitoring research programme. Running from 2017 to 2022, it was co-financed by the EU's Horizon 2020 Research and Innovati...

Incidence and predictors of delirium-associated violence towards healthcare workers in a Swiss ICU: results from the CAVE study

Abstract Background To assess the frequency of delirium coinciding with aggressive and/or violent patient behavior in intensive care unit (ICU) patients as documented by nurses and to identify clinical associations or risk factors. Methods This was a retrospective observational c...

Surgeon task load, ergonomics, and clinical outcomes in laparoscopic versus robotic-assisted inguinal hernia repair: a systematic review and meta-analysis of randomized controlled trials

Abstract Conventional laparoscopic inguinal hernia repair (LIHR) is common and robotic-assisted techniques (RIHR) are increasingly being implemented. Current literature is indecisive on whether RIHR offers clinical and ergonomical benefits. This systematic review compares LIHR an...

Transient receptor potential channel activation targets multiple stages of the schistosome parasite

Schistosomiasis, a neglected tropical disease caused by infection with parasitic blood flukes of the genus Schistosoma , affects more than 250 million people worldwide. Currently, patients rely on a single medicine, praziquantel (PZQ), discovered half a century ago. To combat dru...

Pharmacological Individuality: The Twists and Turns of My Journey

The intent of this review is a nearly chronicle tale of my life as a physician-scientist, recounting the events, fortuitous encounters, and sites that shaped my career. Intrigued as a clinician by the large individual variation in response to drug therapy, my research efforts cen...