University Medical Center Hamburg-Eppendorf

Female psychiatrists on screen: Cinematic stereotypes and therapeutic authority, 1935–2021

Throughout the 20th century, women entered psychiatry, yet cinematic representations remained structured by masculinised archetypes such as Dr Evil, Dr Wonderful, and Dr Dippy. This article interrogates depictions of female psychiatrists in nineteen films and one paradigmatic tel...

“We could do more”: exploring violance prevention measures in German outpatient primary care — a qualitative study

Healthcare workers in general practice are exposed to verbal and physical violence from patients and accompanying persons. While research has predominantly focused on hospital settings, evidence on violence prevention in primary care remains limited. General practice staff often...

Current Techniques for Inorganic Polyphosphate Detection and Characterisation

Polyphosphate (polyP) is an evolutionarily conserved linear polymer of orthophosphate residues with diverse functions across organisms from bacteria to mammals. In addition to its roles in phosphate and energy storage, polyP has been implicated in thrombosis, inflammation, cancer...

Felt and expressed needs regarding occupational health services from the perspective of micro-, small and medium-sized enterprises: a scoping review

BACKGROUND: In the context of the changing need for health care and prevention due to climate, digital and demographic change, occupational health services are of enormous relevance, as many people can be reached. Of particular interest are the occupational health services in mic...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...

Differences in health outcomes of orthopedic rehabilitation after hip or knee replacement: a prospective pilot study benchmarking 23 rehabilitation facilities using Patient-Reported Outcome Measures (PROMs)

Abstract Background Patient-reported outcome measures (PROMs) are increasingly used for benchmarking hip and knee arthroplasty, yet evidence on their feasibility for public reporting of short-term rehabilitation outcomes remains limited. International initiatives such as ICHOM re...

β1- and β2-adrenergic receptor mediated spontaneous contractions and ryanodine receptor channel opening in human failing heart

Abstract In heart failure, β-adrenergic receptor (β-AR)-Gsα-cAMP-protein kinase A (PKA) signalling predisposes to delayed-afterdepolarisation-mediated arrhythmias. Phosphodiesterases (PDEs) hydrolyse cAMP, and PDE3 restrains β 1 -AR, β 2 -AR-mediated inotropic responses in failin...

The emergence of hybrid super-resolution microscopy

Abstract Super-resolution microscopy (SRM) has transformed biological imaging, yet many techniques remain constrained by limited accessibility. Expansion Microscopy (ExM) and fluorescence fluctuation-based super-resolution microscopy (FF-SRM) methods provide complementary strateg...