Institution
Université Paris-Saclay
Recent research
- Engineering & Technology
Abstract Injector staging has recently been demonstrated to control thermoacoustic instabilities in an annular combustor, but its effects were investigated at a single operating point. This work extends this concept to a wide operating domain comprising a range of thermal powers...
- BiologyOpen access
Triple-negative breast cancer (TNBC) accounts for 10–15% of newly diagnosed breast cancer, and its aetiology is poorly understood compared to other breast cancer subtypes. We applied untargeted metabolomics to identify novel biological pathways associated with TNBC risk and poten...
- Health & MedicineOpen access
Background/Objectives: Medication safety is a critical concern in older adults due to age-related vulnerability, multimorbidity, and polypharmacy. Pro Re Nata (PRN, “as needed”) prescribing is common in geriatric care but may be interpreted inconsistently across healthcare profes...
- Climate & EnvironmentOpen access
Brick kilns across India: A temporal analysis of brick kiln distribution and technology types
Thousands of brick kilns operate across India, significantly contributing to air pollution and CO 2 emissions due to outdated practices and non-compliance with environmental standards. Regulations promoting cleaner kiln technologies have been introduced, yet detailed information...
- Physics & SpaceOpen access
Abstract We investigate the impact of phenomenological prescriptions in the Collins–Soper–Sterman (CSS) approach for global extractions of Transverse Momentum Distributions (TMDs). We show that fits to low-energy Drell–Yan data with different choices of $$b_*$$ <mml:math xmlns:mm...
- Health & MedicineOpen access
Minimally invasive surgical approaches have gained widespread adoption, yet comparative evidence integrating multiple hierarchical endpoints remains limited. Our objective was to compare the surgical approaches for lung cancer resection (thoracotomy, VATS, robot-assisted surgery)...
- Physics & SpaceOpen access
Electrical control of exchange bias in sub-10 nm regime enabled by single-nanotube patterning
Achieving stable magnetization in sub-10 nm ferromagnetic layers represents a fundamental bottleneck in spin-orbit torque magnetic random-access memory development. While exchange bias potentially offers stabilization at such scales through antiferromagnetic coupling, conventiona...
- Climate & Environment
Visible mould and blood inflammatory phenotypes of asthma in adults: the CONSTANCES cohort
Studying the associations between indoor mould contamination and blood inflammatory phenotypes may provide further insight into the mechanisms by which this environmental factor affects asthma. Among 1870 adults with current asthma from a population-based cohort, 29.6% reported v...
- Engineering & Technology
Abstract Reducing carbon footprint of the aviation sector is essential for its sustainability. A promising solution for short-to-medium-haul flights is to replace kerosene with hydrogen combustion. This switch leads to significant changes in the architecture of the combustion cha...
- Physics & Space
The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...
- Climate & EnvironmentOpen access
Abstract Thin-film nanocomposite (TFN) membranes have received significant attention because of their excellent separation performance, structural flexibility, and tunability. As the demand for high-efficiency membrane technologies in industry grows, it becomes imperative to tran...
- Climate & EnvironmentOpen access
Accelerating biomass loss from forest disturbances across Europe
Abstract Forest disturbances are rising globally due to climate change and land-use pressures, weakening the terrestrial carbon sink. However, declines in aboveground biomass from tree cover loss remain poorly quantified, limiting our understanding of the role of disturbances in...
- Materials & EnergyOpen access
Mitochondrial dysfunction is a primary pathogenic mechanism underlying dopaminergic neuron loss in the nigrostriatal pathway in Parkinson's disease (PD). To investigate mitochondrion-targeted therapeutic strategies, we utilized the MitoPark mouse model, in which mitochondrial tra...
- Climate & EnvironmentOpen access
Abstract. Reduced-Complexity Models (RCMs) are a critical tool for synthesising climate science knowledge and providing climate projections for a wide range of emissions scenarios. The Reduced-Complexity Model Intercomparison Project (RCMIP) provides a framework for the coordinat...
- Health & Medicine
Accelerating Translation of NK Cell Therapies to the Clinic: A European Perspective
Adoptive immunotherapies have emerged as a promising strategy in the treatment of hematological malignancies. To date, seven chimeric antigen receptor (CAR)-T cell products have obtained market authorization in Europe for B-cell malignancies, where they have revolutionized treatm...
- BiologyOpen access
OBJECTIVES: This study analysed a large French collection of carbapenemase-producing Klebsiella oxytoca complex (KoC) isolates (2017-2023) to map species and carbapenemase distributions and identify emerging lineages. We further investigated virulence traits to understand the epi...
- BiologyOpen access
Nested contextual change and the temporal compression of episodic memory
Abstract How does the structure of events influence the when and the where of life experiences in comparison to the what? We developed a novel virtual reality (VR) environment to understand how the quantity of information within nested structures influence participants’ memory fo...
- BiologyOpen access
Fibroblast growth factor receptor 3 ( FGFR3 ) is one of the most frequently altered genes in bladder cancer, primarily through activating mutations that drive oncogenesis and are enriched in luminal tumors. However, the underlying gene regulatory network (GRN) remains poorly char...