Universidade do Porto

Event-related potentials reveal enhanced processing of social media over monetary rewards

Since the first online social media platform, using social media has emerged as one of the defining behaviors of the new millennium. For most users such behavior is recreational. However, for some individuals, the use of social media may develop to problematic, compromising their...

Viperin as a putative antiviral effector in rainbow trout (Oncorhynchus mykiss) cells identified by CRISPR-Cas9 functional analysis following exposure to inactivated viral hemorrhagic septicemia virus

Abstract Viperin is recognized for its potent broad-spectrum antiviral activity; however, its role in the antiviral immune response of rainbow trout ( Oncorhynchus mykiss ) remains poorly characterized. In this study, the contribution of viperin to the innate immune response agai...

Dynamics of the Leftmost Particle in Heterogeneous Semi-infinite Exclusion Systems

We study the behaviour of the leftmost particle in a semi-infinite particle system on Z, where each particle performs a continuous-time nearest-neighbour random walk, with particle-specific jump rates, subject to the exclusion interaction (i.e., no more than one particle per site...

Validation of the Individuation Test for Emerging Adults-Short (ITEA-S) in Spanish and Portuguese Emerging Adults

We evaluated the factorial validity and reliability of the Individuation Test for Emerging Adults–Short (ITEA–S) among Spanish ( n = 373) and Portuguese ( n = 351) emerging adults. Results of confirmatory factor analyses supported the original five-factor structure (Support Seeki...

Emergency Construction in Remote Locations Using Large-Scale 3D Printing: Literature Review and Research Perspectives

Large-scale 3D printing has emerged as a potentially transformative technology for emergency construction in remote and disaster-affected areas, offering rapid, sustainable, and economically viable solutions. This article presents a literature review examining the advances, chall...

Effect of Dentin Pretreatment Strategies on Bond Strength to Natural Caries-Affected Dentin: A Systematic Review

Background: This systematic review aimed to evaluate the effect of dentin pretreatment strategies on bond strength to natural caries-affected dentin (NCAD) in permanent human teeth. Methods: A systematic search was conducted in PubMed, Web of Science, and Scopus databases up to A...

Nature-Based Solutions for Office Workers: A Randomized Controlled Trial on Indoor Plants to Enhance Well-Being and Productivity

Most of the global population lives and/or works in urban areas with limited access to green spaces. Integrating nature-based solutions (NBS) into indoor environments has emerged as a promising intervention strategy for enhancing indoor environmental quality (IEQ) and promoting h...

From Transparency to Transport: Optoelectronic and Interfacial Signatures of n-Type ITO, FTO, ZnO and TiO2 Semiconductors

Transparent conducting oxides and electron transport layers are central to optoelectronic devices, yet their interfacial electronic behavior remains strongly dependent on substrate chemistry, defect states, and surface potential alignment. Here, we compare ITO and FTO transparent...

Navigating Uncharted Waters: Steering the Course and Confronting Challenges of Brain Metastases in EGFR-Mutant Non-Small Cell Lung Cancer

Brain metastases represent a major clinical challenge in the management of non-small-cell lung cancer, particularly in patients with epidermal growth factor receptor mutations, constituting a leading cause of morbidity and mortality. In recent years, significant advancements have...

Running-Related Injuries in Recreational Runners: Prevalence, Anatomical Distribution, and Associated Physiological and Training Factors

Background: Running-related injuries are a common issue among recreational runners and may affect training continuity and long-term participation. However, injury-associated factors remain unclear due to methodological heterogeneity and reliance on self-reported data. Objective:...

Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates

ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic...

Preclinical Evaluation of Combined Polo-like Kinase 1 Inhibition and Navitoclax in Experimental Models of Lung Cancer

Targeted therapies have substantially advanced cancer treatment; however, therapeutic resistance remains a major challenge, particularly in lung cancer. Polo-like kinase 1 (PLK-1), a key regulator of mitosis, is frequently overexpressed in lung tumors and has emerged as an attrac...

Recovery and characterization of a field derived Bagaza virus with broad cellular host range

Abstract Bagaza virus (BAGV) is an emerging orthoflavivirus that primarily infects wild birds, but its ability to infect other hosts remains poorly understood. We isolated infectious BAGV from the brain of a dead red-legged partridge by transfection of extracted viral RNA and eva...

Bivalve Gut Microbiome Responses to Sediment Characteristics and Anthropogenic Activities in Cerastoderma edule (Linnaeus, 1758)

Abstract Estuaries are dynamic ecosystems influenced by fluctuating environmental conditions and sediment-associated contamination, which may affect host-associated microbiomes. This study investigated the gut microbiome of the bivalve Cerastoderma edule across three estuarine si...

Reconfiguring University Missions in the Knowledge Society: The Case of Portuguese Universities in European Alliances

ABSTRACT This paper examines how European Knowledge Society policy scripts, amplified by the European Universities initiative, are appropriated in the strategic plans of Portuguese public universities. Focusing on nine universities participating in European Universities Alliances...

Validation of the DIVAS-Q (Day-to-Day Impact of Vulvovaginal Atrophic Symptoms Questionnaire): a Portuguese patient-reported outcome measure

Abstract Introduction Portuguese is the fifth most spoken language worldwide. However, no validated patient-reported outcome measure (PROM) is available to assess the impact of vulvovaginal atrophy (VVA) symptoms in Portuguese-speaking women. This study aimed to culturally adapt...

Effectiveness and Safety of a Self-Management Program for Substance Addiction Consequences: A Pilot Clinical Trial

Background: Harmful substance use affects millions of people, producing health and social consequences that require both professional support and effective self-management. This study piloted a self-management program targeting the consequences of substance addiction in adults en...

Active Screening for C. auris Colonisation: A Preventive Step or an Excessive Measure? A Systematic Review

Background: Patients’ and surfaces’ colonisation play a pivotal role in C. auris transmission. Understanding how, when, and where screening for colonisation should be done is important to control the spread. Methods: This systematic review searched studies regarding C. auris pati...

A Multimodal Framework for Analyzing Engagement With Green Social Media Influencers

ABSTRACT In light of growing concerns about environmental degradation and unsustainable consumption patterns, effective communication about sustainability has become crucial in encouraging more environmentally conscious behavior. With their ability to connect with large audiences...

Measuring masses of transiting Earth-like planets: first insights from the PLATO RV Data Challenge

Abstract The PLATO Stellar Variability Mitigation Working Group designed a radial-velocity (RV) data challenge to assess the precision and accuracy achievable on RV semi-amplitudes in the context of the future PLATO follow-up. Using Sun-as-a-star observations obtained with HARPS-...