Tongji University

The fluoride channel genes crcB1 and crcB2 contribute to high-level fluoride resistance and virulence in Staphylococcus aureus

Staphylococcus aureus ( S. aureus ) can colonize the oral cavity and cause infections ranging from localized disease to systemic illness. Fluoride is widely used in oral care for caries prevention and can inhibit many oral microorganisms. However, S. aureus exhibits high-level fl...

Aging and Antiaging Mechanisms of Nano-ZnO–Modified Asphalt under Various Aging Conditions

Abstract Natural solar radiation, high temperatures, and precipitation act synergistically to induce progressive aging in road asphalt. The incorporation of nano-ZnO has been shown to enhance the asphalt’s resistance to aging. Thus, this study aims to investigate the aging behavi...

Donor-Type-Dependent Heterogeneity of Ischemia–Reperfusion Injury in Lung Transplantation: A Multi-Cohort Transcriptomic Interaction Analysis of DCD Versus DBD Lungs

Background: Donation after circulatory death (DCD) and donation after brain death (DBD) donor lungs are widely used in lung transplantation yet managed as equivalent with respect to ischemia–reperfusion injury (IRI), despite fundamentally different ischemic backgrounds: warm isch...

A Hybrid Framework Combining Autoregression and Common Factors for Matrix Time Series

Matrix-valued time series are ubiquitous in modern economics and finance, yet modeling them requires navigating a trade-off between flexibility and parsimony.We propose the Matrix Autoregressive model with Common Factors (MARCF), a hybrid structured Reduced-Rank Matrix Autoregres...

Mitophagy induction promotes the maturation of hiPS-derived cardiomyocytes

Mitophagy dysfunction is an important contributor to the occurrence of cardiovascular diseases. Parkin-mediated mitophagy directs perinatal cardiomyocyte metabolism maturation, but its role during the earlier stage of cardiomyocyte differentiation is not fully elucidated. Human-i...

Result-Oriented Generation Meets Process-Oriented Creation: Understanding the Tension Between Generative AI and Craft Practice

Generative artificial intelligence (GenAI) is reshaping creative work, yet research focuses mainly on digital creation, with limited attention to embodied practices grounded in material interaction and physical making. Taking craft as an entry point, we examine GenAI in craft thr...

Facing inevitable decline: a systematic review and thematic synthesis of progression-related fears in amyotrophic lateral sclerosis

Abstract Background Amyotrophic lateral sclerosis (ALS) is characterised by inevitable and continuous deterioration, yet the psychological experience of anticipating future decline has not been systematically synthesised. Although qualitative studies have described loss, uncertai...

Anion‐Programmed Lewis‐Acidity‐Amplified Cellulose Separators for Dual Interphase Regulation in Li||NCM811 Batteries

ABSTRACT Separators in lithium metal batteries are typically treated as passive ion‐transport membranes, despite their strategic position between two unstable electrode‐electrolyte interfaces. Inspired by Lewis acid‐base regulation in liquid/ solid state electrolyte systems, we r...

Interaction-enhanced lane-change early warning in congested traffic: a spatial risk propagation-aware approach

This paper presents an interaction-enhanced Lane-Changing Early Warning (LCEW) system designed to issue reliable early warning signals through a spatial risk-propagation-aware approach. The system is built upon interpretable multi-vehicle trajectory predictions and collision risk...

Characteristics and Genetic Types of Authigenic Quartz in Paleogene ES 3 and ES 4 Shales, Dongying Sag

ABSTRACT Authigenic quartz is a key mineral controlling reservoir quality and rock brittleness in continental shales; however, its silica sources and diagenetic evolutionary pathways in lacustrine fine‐grained sediments remain insufficiently constrained. Taking the Paleogene ES3...

Coupled Surface and Pore Diffusion of Neutral Organic Molecules in Nanopores

Abstract The transport of neutral organic molecules through nanoscale pores is central to a wide range of processes, yet the molecular factors governing their mobility remain difficult to predict. Here, we use all-atom molecular dynamics simulations under a nonpolarizable force f...

A Two-Layer Simulation-Based Optimization Framework for Coordinated Metro Rescheduling: Integrating Machine Learning Surrogates with Metaheuristics

Abstract Metro systems are prone to unplanned disruptions that can trigger cascading delays across the network, particularly when transfer stations are involved. Existing rescheduling approaches often treat the disrupted line in isolation or rely on indirect operational metrics (...

Targeting endothelial CYP3A5 in lung adenocarcinoma remodels the immunosuppressive microenvironment via VEGF inhibition: Mechanistic insights from Diosmetin

The tumor endothelium not only promotes angiogenesis but also actively fosters an immunosuppressive microenvironment in lung adenocarcinoma (LUAD). Cytochrome P450 enzymes, particularly CYP3A5, have emerged as potential regulators of endothelial function, yet their role in shapin...

Effect of CO2–Water–Coal Coupling on the Mechanical Stability of Deep Coal Seams

Abstract CO2 geological storage in deep coal seams provides dual benefits of carbon storage and enhanced coalbed methane recovery. However, the CO2–water–coal interactions during storage significantly deteriorate the coal’s mechanical properties through swelling and softening mec...

Mapping Multimodality in Translation Studies: A Systematic Review

ABSTRACT This systematic review examines recent developments in how multimodality has been conceptualised and investigated within translation studies, based on 113 articles identified through a search of 14 selected translation journals published between 2019 and 2024. Four main...

Multi-layer predictor feedback design for nonlinear integro-differential equations with state-dependent input delays

We develop a novel multi-layer predictor feedback to achieve exact compensation of state-dependent input delays of general nonlinear integro-differential equations. The system of interest is an unconventional mixed Partial Differential Equation (PDE)-Ordinary Differential Equatio...

Seismic Assessment of a Full-Scale Perimeter-Fixed Ceiling with Hook-And-Loop-Secured Lay-In Tiles Using Shake Table Tests

Grid-and-tile ceiling systems are widely installed in commercial buildings but have frequently experienced damage in past earthquakes, resulting in safety risks, costly repairs, and operational interruptions. The present study examines the seismic performance of a perimeter-fixed...

Active Droplet Formation in a Microfluidic Cross-Junction Using Stacked Piezoelectric Actuators

On-demand droplet formation is of crucial importance to the engineering applications of droplet microfluidics. This work presents an experimental investigation on active control of droplet formation using stacked piezoelectric actuators. Two stacked piezoelectric actuators are pl...

Station-Based Evaluation of AI Weather Models for Near-Surface Temperature, Pressure, and Wind Forecasts over Eastern Coastal China

Accurate prediction of near-surface meteorological variables is important for weather services and coastal risk management. However, the station-level performance of global artificial intelligence (AI) weather models remains insufficiently characterized in complex coastal environ...

Allergic Rhinitis: From Pathology to Novel Therapeutic Approaches

Allergic rhinitis (AR) is a common chronic inflammatory disorder of the upper airway in which allergen sensitization interacts with epithelial, neural, and immune responses, as well as comorbidity and treatment context, to shape clinical expression[...]