Tongji University

Machine learning–driven structural health monitoring of a high-rise building on thick sediments via seismic ambient noise

Seismic ambient noise enables non-invasive monitoring of high-rise buildings, but existing indicators trade floor-level localization for operational simplicity. Resonance-frequency changes track whole-building stiffness but poorly localize structural variations, whereas inter-flo...

Formation of a silica scaffold with a hyperbolic surface structure as a time-frozen glimpse by ultraviolet curing

Abstract Triply periodic hyperbolic surfaces have been extensively investigated in various natural and artificial self-assembled systems and have attracted great attention because of their complexity and geometrical beauty. However, understanding their formation during bottom-up...

In Situ Growth of Silver Nanoparticles in Electrospun Polyvinylidene Fluoride Composite Membranes for Photocatalytic Degradation of Dyes and Antibiotics

Photocatalytic degradation technology has been widely acknowledged for its low cost and high degradation efficiency. However, the loss, migration and difficult recovery of powdered catalysts are still critical bottlenecks for practical applications. In this study, silver nanopart...

A self-driven probiotic nanosystem reshapes extracellular matrix by knockdown of DDR1 for enhanced tumor immunotherapy

Immunotherapy represents a promising therapeutic approach for tumor suppression, yet its efficacy is significantly limited by the immunosuppressive extracellular matrix (ECM) characteristic of solid tumors. To achieve simultaneous ECM remodeling and immune activation within a sin...

Mefatinib versus gefitinib as a first-line treatment for EGFR-mutated non-small cell lung cancer: a randomized, double-blind, multicenter phase III study

Mefatinib, a novel second-generation epidermal growth factor (EGFR) tyrosine kinase inhibitor that has shown promising antitumor activity in targeting non-small cell lung cancer (NSCLC) with common and uncommon EGFR- activating mutations. In this phase III, randomized, double-bli...

Non-Linear Impacts and Spatial Variations in Multidimensional Built Environments on E-Shopping Decisions: Evidence from Shanghai

While e-commerce has transformed consumption patterns, online shopping behavior remains influenced by the physical environment. Using Shanghai as a case study, this research applies machine learning, SHAP analysis, and K-Means clustering to examine the nonlinear impacts and spati...

Metal–OrganicFrameworks (MOFs) for the Deliveryof Small-Molecule Therapeutics

Abstract As cutting-edge porous materials, the properties of metal–organic frameworks (MOFs) are governed by their metal nodes and organic linkers, as well as the assembly mode of these subunits. This allows the loading capacity of MOFs for small-molecule drugs to be readily tail...

METTL3-mediated m6A modification of TP73-AS1 enhances HCC progression by activating Wnt/β-catenin signaling

Long noncoding RNAs (lncRNAs) play key roles in the onset and progression of hepatocellular carcinoma (HCC). Tumor protein 73 antisense RNA 1 (TP73-AS1), a recently identified lncRNA, has been implicated in cancer occurrence, drug resistance, and prognosis; however, its function...

Mechanical Response and Damage Behavior Analysis of Asphalt Pavements Using a 3D Coupled Thermomechanical Multiscale Modeling Method

Abstract Asphalt concrete (AC) exhibits complex damage behavior under the combined effects of environmental factors and loads. Phenomenological models may encounter difficulty in deeply explaining its damage evolution mechanisms. To solve this issue, this study developed a multis...

Integrated Risk Assessment of Landfill Flowslides: Sensitivity Analysis of the Initiation Mechanism and Hazard Potential

Abstract Numerous landfill flowslide disasters have occurred globally, posing a significant threat to the environment and human lives and property. The progressive evolution of flowslides, encompassing both the slope failure and postfailure motion stages, is influenced by waste p...

Photoinduced Switching-onof Intermolecular FerromagneticExchange in a Cobalt–Viologen Donor–Acceptor Assembly

Abstract Crystal engineering of anisotropic molecular solids that translate photoinduced charge transfer into switchable magnetic exchange offers a route to optically addressable exchange-correlated magnetic states. Here, we show that (MV)[Co(pdms)2](MeOH)2(MeCN), a donor–accepto...

Clinical predictors of early treatment response across systemic therapies in psoriasis: a prospective cohort study

Background Baseline clinical factors may help estimate early response in psoriasis, but real world evidence across biologics, methotrexate, and phototherapy remains limited. We used SPEECH registry data to evaluate factors associated with Physician Global Assessment (PGA) ≤ 1 at...

MonovalentIon SelectivityIncomparability of GrapheneOxide Membrane in Different Separation Systems: A Microscopic Understanding

Abstract Precise monovalent ion sieving is essential for water treatment and resource recovery. However, ion selectivity reported from diffusion-based and electro-driven membrane processes is often inconsistent and difficult to reconcile due to unclear mechanistic understanding....

Visual Branding and the Politics of Gentrification: Barcelona through Three Urban Mirrors

When I first arrived in Barcelona, the city seemed unusually aware of its own image. Its pavements, façades, monuments, shopfronts, housing photographs, and museum narratives form a visual system that makes the city easy to recognise and consume. This essay asks what that system...

Visual Branding and the Politics of Gentrification: Barcelona through Three Urban Mirrors

When I first arrived in Barcelona, the city seemed unusually aware of its own image. Its pavements, façades, monuments, shopfronts, housing photographs, and museum narratives form a visual system that makes the city easy to recognise and consume. This essay asks what that system...

MXene-Based Conductive Microneedle Patch Promotes Diabetic Wound Healing by Regulating Oxidative Stress and Immune Microenvironment

Abstract Excessive reactive oxygen species (ROS) generation and the release of inflammatory mediators create a pathological microenvironment in diabetic wounds, severely impairing the healing process. Coupling endogenous electric fields has shown great therapeutic potential for i...

Chemotherapy remains effective in ALK-TKI therapy: a retrospective analysis in ALK-positive advanced NSCLC

Tyrosine kinase inhibitors (TKIs) are the standard therapy for advanced non-small cell lung cancer (NSCLC) harboring anaplastic lymphoma kinase (ALK) fusions. However, acquired resistance remains a major challenge, necessitating strategies to prolong therapeutic efficacy. This st...

Monolithic AgX/Biomass Carbon Aerogels (X = Br, Cl) for Recyclable Photocatalytic Degradation of Multiple Pollutant Classes

While silver halides (AgX) are promising visible-light photocatalysts for water remediation, their practical deployment is severely hindered by intrinsic photocorrosion, rapid charge recombination, and macroscopic recovery challenges. Here, we demonstrate a monolithic AgX/biomass...

Targeting the ANKRD54/ELOVL6 axis suppresses malignancy in BRAF mutant colorectal cancer by disrupting fatty acid metabolism and promoting ferroptosis

Abstract Background BRAF-mutant (BRAF-MT) colorectal cancer (CRC) represents a clinically aggressive subtype characterized by distinct biological features and significantly worse prognosis compared to BRAF wild-type (BRAF-WT) CRC, with median survival reduced by approximately 40%...

Elastic modulus recovery in concrete incorporating biomimetically mineralized recycled aggregates

Abstract The structural application of recycled aggregate concrete (RAC) is severely hindered by its low elastic modulus, primarily caused by porous adhered mortar and defective interfacial transition zone (ITZ). This study proposes a novel biomimetic mineralization strategy to c...