Tongji University

Spatially Decoupled Cascade Oxygen Reduction on Bi Single‐Atom and Cluster‐Hybrid Sites for Hydroxyl Radical Generation

ABSTRACT The two‐electron oxygen reduction reaction (2e − ORR) for H 2 O 2 production and the subsequent in situ activation to ·OH are constrained by linear scaling relationships, making it difficult for a single active site to simultaneously optimize O 2 activation and H 2 O 2 c...

CD147+ Cancer‐Associated Fibroblasts Promote PD‐L1 Expression in Hepatocellular Carcinoma via TIMP2/MMP2/IL‐6 Signaling

BACKGROUND: Targeting CD147 on hepatocellular carcinoma (HCC) cells has demonstrated therapeutic efficacy. Cancer-associated fibroblasts (CAFs) have been identified as critical components of the tumor microenvironment. The role of CD147 in CAFs is still unclear, and this study ai...

Empowering Drivers as Collaborative Social Agents: Enhancing Pedestrian Interaction through Cooperative Interfaces in Autonomous Vehicle Systems

While autonomous driving technology reduces the operational burden on drivers, it may also diminish their sense of engagement, for example, by interrupting social interactions between drivers and other road users such as pedestrians. To address this, this article proposes a “Soci...

Prediction and optimization of tire-pavement noise for ultra-thin friction course based on surface texture

Tire–road noise is a major component of traffic noise and becomes increasingly dominant under medium- and high-speed driving conditions. Pavement surface texture plays a critical role in tire–road noise generation; however, existing prediction approaches remain limited in capturi...

Metacognition and pathway dynamics in generative AI supported design thinking: A process-sensitive evaluation with network-based cognitive mapping

Generative AI (GenAI) is embedded in design education, yet little is known about how different tools reshape metacognition and the pathways linking ideas to outcomes. We compare three conditions, ChatGPT-4o, DeepSeek-R1, and a no-AI control, in a virtual reality cultural heritage...

A reduced angular-coordinate equilibrium formulation with exact embedding of prescribed angular data for inextensible Kirchhoff rods

In the reduced-order static analysis of inextensible Kirchhoff rods, locally prescribed tangent directions and material-twist angles are still often enforced only after discretization as external constraints. This increases the constrained-system burden and can offset the benefit...

UBE2K-FBXO11 complex activates Wnt signaling by stabilizing β-catenin through lysine 63-linked polyubiquitination

Abstract Β-catenin is regulated by phosphorylation and lysine (K)48-linked ubiquitination, which target it for proteasomal degradation. While the degradation machinery of β-catenin, including the destruction complex, has been extensively studied, regulators that stabilize β-caten...

Photo‐Controlled Treatment for Psoriasis‐Like Skin Lesions by UVB‐Photoactivated Hydrogen Sulfide Donors and Pterostilbene

ABSTRACT Smart and efficient drug delivery is always desirable, especially for chronic diseases, such as psoriasis. We developed an ultraviolet B (UVB) light‐triggered scaffold, 1,4,2‐dioxazol‐5‐thione (DOT), for the controlled release of hydrogen sulfide (H 2 S), a pivotal endog...

Differentiated time-frequency envelope kurtosis-gram guided adaptive variational multi-harmonic mode extraction for fault diagnosis of offshore wind turbine slewing bearings

Early fault characteristics of offshore wind turbine slewing bearings are weak and easily masked by noise, making accurate extraction difficult. To address this problem, a differentiated Time-Frequency Envelope Kurtosis-gram (TFEKgram) guided Adaptive Variational Multi-Harmonic M...

Lactylation‐Mediated HER2 Stabilization Promotes Trastuzumab Resistance in Gastric Cancer

ABSTRACT Trastuzumab is the standard first‐line targeted therapy for human epidermal growth factor receptor 2 (HER2)‐positive gastric cancer (GC). Unfortunately, its clinical efficacy is often compromised by the development of drug resistance. The Warburg effect, a hallmark of ca...

Mediating Soviet architecture in China, 1930s–1940s: translation, intermediation, and knowledge circulation

The paper examines the introduction and representation of Soviet architecture in Chinese mass media and professional journals during the 1930s and 1940s. It analyzes how Soviet experiences in urban construction and architectural theory were translated, interpreted, and integrated...

RISMO: Riemannian Information-Geometric Swarm Motion Orchestration for Heterogeneous UAV–UGV Cooperative Exploration in Unknown Environments

Abstract The orchestration of heterogeneous swarm systems, such as Unmanned Aerial Vehicle (UAV) and Unmanned Ground Vehicle (UGV) teams, in unknown, GPS-denied environments requires coordination among active perception, collision avoidance, and topological flexibility. Tradition...

Influence of Grain‐Scale Heterogeneity on Crack Propagation in Crystalline Rocks Based on Phase‐Field Modeling

ABSTRACT The mesoscopic heterogeneity of crystalline rocks, primarily manifested in mineral distribution and content, critically controls crack path selection and macroscopic strength. However, a mechanistic and quantitative understanding of these grain‐scale controls remains lim...

Persistent Mn 3+ Sites on Reduced MnO Enable Efficient Syngas Conversion

ABSTRACT Mn‐based materials are widely used for syngas conversion, where MnO is generally regarded as the catalytically active phase under reducing conditions. Yet catalysts derived from different Mn oxide precursors often exhibit markedly different performances despite evolving...

Alkylene Spacer Engineering for Boosting Circularly Polarized Luminescence in Homopolypeptide Self-Assembly

Abstract Functional materials with circularly polarized luminescence (CPL) property featuring both high luminescence efficiency and strong chiroptical activity are highly desirable for advanced photonic applications such as three-dimensional displays, optical encryption, asymmetr...

Spatially Uneven and Seasonally Intensified Water Competition Between Agriculture and Energy Production in China

data_Gridded_water_withdrawal.zip: gridded monthly water withdrawal data for China at a spatial resolution of 0.1° × 0.1°, covering the agriculture, coal mining and washing, coking, and thermal power generation sectors, for the years 2000, 2010, 2015, 2019, and 2024 data_WCI.zip:...

Sliding friction-based lateral-gravity decoupling system for concrete modular building

Balancing seismic performance with degree of prefabrication remains a primary challenge in concrete modular buildings. Existing connection methods have difficulty achieving both high prefabrication efficiency and reliable seismic performance. Conventional connections either incre...

Targeting REV7 confers cervical cancer cell radiosensitivity and ferroptosis by negatively regulating SFXN1

Cervical cancer is the 4th most common malignancy in women. Radiotherapy (RT) plays an essential role in cervical cancer treatments, and this study reports the role of REV7 in cervical cancer RT. Results showed that loss of REV7 contributed to increased the radiosensitivity of ce...

How Industry Types Shape Commuting and Non-Commuting Network Centrality: A Geographical Detector Analysis of Shanghai and Its Adjacent Areas

The polycentric spatial structure of metropolitan areas has become a frontier topic in urban studies. Yet existing research has largely remained descriptive regarding commuting networks, with limited investigation into how different industry types are associated with commuting an...

Modeling non-equilibrium water-ethanol condensation: Ideal and non-ideal approaches

Accurate prediction of non-equilibrium wall-film condensation of water-ethanol mixtures in Baijiu distillation condensers is essential for reliable modeling of heat and mass transfer. Yet, it remains challenging because of strong coupling among vapor partial pressures, saturation...