Tongji University

Hepato-Immune Crosstalk Underlies Antipsychotic-Associated Metabolic Dysregulation in Schizophrenia: Quercetin as a Therapeutic Candidate for High-Inflammatory Subtypes

Background: Patients with schizophrenia (SCZ) receiving antipsychotic treatment frequently develop metabolic complications, yet the mechanisms underlying liver-immune crosstalk remain poorly characterized. Methods: This study recruited 340 antipsychotic-treated SCZ patients and 3...

Sleep-disordered breathing is associated with Blood-brain barrier markers across the Alzheimer’s disease spectrum

Sleep-disordered breathing (SDB) is prevalent among older adults and is increasingly recognized as a modifiable risk factor for cognitive decline and Alzheimer’s disease (AD). Blood-brain barrier (BBB) dysfunction is an early and mechanistically relevant feature of AD pathophysio...

Targeted suppression of VOCs and particulate matter emissions from desulfurized crumb rubber modified asphalt using kaolin-expanded graphite composite adsorbents

Desulfurized crumb rubber modified asphalt (DCRMA) improves the compatibility and workability of waste-tire rubber in asphalt, but the associated change in fume composition has not been well defined. This study first compared the temperature-dependent emissions of conventional cr...

Stochastic mesoscale modeling of chloride ingress in coastal concrete structures under climate change

Climate change is intensifying chloride-induced corrosion in marine reinforced concrete (RC) structures, yet conventional durability assessment fails to capture the coupled effects of material heterogeneity, environmental variability, and thermo-hygro-ionic transport. This paper...

Machine learning-enabled prediction and interpretation of spectroscopic properties in Nd and Y co-doped fluorite platform via local coordination engineering

The design of advanced laser materials demands precise control over the relationship between local structure and spectroscopic performance. However, conventional approaches struggle to quantitatively link complex coordination environments with spectral properties in rare-earth-do...

Identifying urban low-altitude traffic corridors: A computational fluid dynamics simulation approach

With the rapid expansion of unmanned aerial vehicle (UAV) applications in urban logistics, inspection, and emergency services, structured low-altitude networks are increasingly needed to support strategic airspace management. This paper proposes a computational fluid dynamics (CF...

Biocatalytic Transformation of Industrial Polyurethane Waste Using Laccases: Toward Environmentally Sustainable Management Strategies for Plastic Pollution

Polyurethane foams (PUFs) account for approximately 5.3% of global plastic production and are highly persistent in the environment due to their resistance to degradation. Their progressive fragmentation into micro- and nanoplastics, together with the presence of hazardous additiv...

Combined femoral nerve block and posterior knee pain-point infiltration for early passive knee training after total knee arthroplasty: a two-center sham-controlled proof-of-concept randomized trial

Abstract Background We assessed whether a combined regional analgesic regimen administered immediately before passive knee training on postoperative day 3 was associated with active knee range of motion (ROM) 90 days after the intervention. Methods In this two-center, parallel-gr...

Structural retrofitting design of Shanghai Indoor Stadium

The data that support the findings of this study are available from the corresponding author upon reasonable request.

REV-based analysis of non-uniform heat transfer in irregular geometries of precast concrete sandwich wall panels

The thermal performance of buildings is largely determined by the weakest point in the envelope. Precast concrete sandwich wall panels are a new type of high-performance, multi-functional integrated component that has been widely adopted. However, local heat loss caused by metal...

Robustness assessment of steel frame structures with novel T-stub connections under lateral impact

The extent to which novel T-stub connections (NTC) enhance the collapse resistance of steel frame structures under lateral impact remains unclear, and there is a lack of a systematic quantitative evaluation approach. To address this issue, a component-based modeling methodology w...

Floor response spectra–oriented acceleration mitigation of base-isolated structures with rate-independent damping

Engineering structures accommodating acceleration-sensitive non-structural equipment exhibit an intrinsic incompatibility in seismic demand control, as base isolation effectively suppresses inter-story drift, whereas the introduction of linear viscous dampers to restrain isolator...

A physics-regularized reliability-aware learning framework for non-contact blink monitoring using millimeter-wave radar

Continuous monitoring of eye-blink activity provides a non-contact behavioral indicator relevant to fatigue-related applications and human-state monitoring. Reliable radar-based sensing remains difficult under the tested single-user office-like desktop conditions because blink-in...

Fatty acid cycling drives metabolic uncoupling and simultaneous nitrogen removal in a low-aeration and no-recirculation activated sludge system

Metabolic uncoupling represents a fundamental strategy for in-situ sludge reduction, yet its underlying metabolic mechanisms under low-aeration conditions remain poorly understood. Here, we investigated activated sludge performance in a reactor with a depth-to-diameter ratio of 4...

Complementary Hydrogel-Based Ionic Thermoelectric Systems for Photovoltaic Waste Heat Harvesting and Energy Storage

Photovoltaic (PV) operation generates substantial low-grade waste heat, motivating energy-recovery strategies that can accommodate dynamically varying thermal conditions. Here, thermogalvanic and thermodiffusive hydrogel-based ionic thermoelectric (iTE) devices were separately in...

Audit-Informed Digital Pathways to Rural Ecological Revitalization: A Configurational Governance Framework Applied to 30 Provincial-Level Regions in China (2018–2022)

Rural regions worldwide face intensifying environmental pressures under the global sustainability transition, yet the digital conditions associated with high levels of rural ecological revitalization (RER) remain insufficiently understood. Existing studies largely examine digital...

Building Footprint Has a Stronger Land Surface Temperature Signal than Building Height across Global Cities

Abstract Urban heat is a growing environmental challenge as cities expand and densify. The thermal meaning of added built volume depends on whether volume is produced through larger building footprint, greater building height, or both. Using 2020 hottest-month land surface temper...

Systemic artery-to-pulmonary artery fistulas and recurrence of noncancer-related hemoptysis after bronchial artery embolization: a retrospective study

To investigate the clinical and angiographic characteristics of systemic artery-to-pulmonary artery fistulas (SA-PAFs) in patients with noncancer-related hemoptysis undergoing bronchial artery embolization (BAE), and to assess their associations with procedural outcomes and recur...

Experimental investigation of mode switching mechanisms and control strategies for combustion instabilities in a rich-lean gas water heater

This study experimentally investigated mode switching of combustion instabilities in a rich-lean gas water heater under varying thermal inputs (18 kW, 24 kW, 30 kW) and flue pipe lengths (1.3 m, 1.8 m, 2.3 m). Pressure measurements, high-speed CH* chemiluminescence imaging, Prope...

Accounting for Nanofilm Contributions in Interfacial Free Energy Calculations Using Classical Density Functional Theory

Abstract Fluid nanofilms play a fundamental role in nanoscale interfacial thermodynamics, yet their interfacial behavior and treatment within classical density functional theory (cDFT) warrant further investigation. We investigate nanofilm interfacial properties using a cDFT fram...