Sorbonne Université

Differentiability of the Value Function in Control-Constrained Parabolic Problems

Abstract. Along the optimal trajectory of an optimal control problem constrained by a semilinear parabolic partial differential equation, we prove the differentiability of the value function with respect to the initial condition and, under additional assumptions on the solution o...

The highly heterozygous European amphioxus (Branchiostoma lanceolatum) at the edge of panmixia

Abstract Amphioxus (Cephalochordata) are small marine chordates that have broad ecological ranges, yet as adults form local settlements and exhibit limited mobility. Genomic surveys of two amphioxus species have suggested that they rank among the most genetically diverse metazoan...

Factors influencing access to healthcare for the indigent in Senegal

Equitable access to health services remains a major challenge to achieving universal health coverage (UHC). In Senegal, the National Family Safety Net Program (PNBSF) aims to reduce vulnerability among poor households through cash transfers and free enrolment in community-based h...

Molecular epidemiology and management of non-tuberculous mycobacteria isolated from patients in Ukraine, 2022–2024

Non-tuberculous mycobacteria (NTM) are increasingly recognized worldwide as significant causes of chronic pulmonary disease, particularly among individuals with underlying structural lung disorders or immunosuppression. However, data on the epidemiology and clinical management of...

Effect of oxygen ion irradiation on the visible, infrared, and Raman spectra of Phobos candidate materials: implications on the space weathering by Martian atmosphere-derived ions

Abstract The origin of Martian satellites is still under debate. Nevertheless, such information could give insights into the evolution of the Martian system and planetary formation processes. To address these questions, MMX (Martian Moons eXploration) will conduct spectroscopy (v...

Hip and groin pain in physically active adults with a focus on terminology, clinical examination and imaging: A formal ESSKA‐EHPA‐ESMA Consensus

Abstract Purpose This European Society of Sports Traumatology, Knee Surgery and Arthroscopy–European Hip Preservation Associates–European Sports Medicine Association (ESSKA‐EHPA‐ESMA) formal consensus aims to provide evidence‐ and expert opinion‐based recommendations for the term...

Evidence of hydrodynamic control of phytoplankton seasonality in a tropical urban estuary

Tropical urban estuaries receive year-round nutrient loads, yet their strongest phytoplankton blooms often occur in the dry season. The proximate control on this seasonality remains unresolved in wastewater-impacted tropical systems. Here we apply a transient one-dimensional Carb...

Actin and myosin dynamics during epithelial remodeling in avian gastrulation

Epithelial remodeling is powered by contractile forces exerted by the actomyosin cytoskeleton. In invertebrates, pulsatile contractile flows of the medio-apical actomyosin cortex have been shown to be critical in promoting junction contraction, ultimately driving cell rearrangeme...

Antifibrotic therapy in patients with pleuroparenchymal fibroelastosis: a multicentric observational study

Pleuroparenchymal fibroelastosis (PPFE) is a rare interstitial lung disease characterized by upper-lobe predominant pleural and subpleural fibrosis and associated with poor prognosis. No evidence-based medical therapy is currently established, and lung transplantation remains the...

Holographic two-point functions of heavy operators revisited

A bstract In this paper we investigate the holographic computation of the two-point functions of $$\frac{1}{2}$$ -BPS chiral primary operators with scaling dimensions ∆ ~ N or ∆ ~ N 2 in 𝒩 = 4 SU ( N ) SYM using Type IIB supergravity. First we consider giant graviton operators, r...

Structural Allograft Reconstruction for Chronic Proximal Hamstring Avulsion Yields Significant Functional Improvement, Acceptable Satisfaction, but Limited Return to Preinjury Sport Levels

Purpose To evaluate midterm outcomes of structural allograft reconstruction in patients with chronic proximal hamstring avulsion injuries. Methods This was a retrospective cohort study (minimum 2‐year follow‐up) including patients who underwent allograft surgical reconstruction f...

Beyond wind-induced upwelling: diverse drivers of future productivity in eastern boundary upwelling systems

Abstract. Eastern Boundary Upwelling Systems (EBUS) contribute disproportionately to global marine productivity and fisheries, yet their response to climate change remains poorly understood. Given the essential ecosystem services they support, improving projections of future EBUS...

The membrane-to-cortex distance regulates mDia1 activity to control cortical mechanics

Abstract The shape of animal cells is controlled by their surface, which comprises the cell cortex, a peripheral actin network, tethered to the plasma membrane by membrane-to-cortex attachment proteins. Changes in cortical components have long been considered to dominate the regu...

Mapping the nuclear environments of extreme coronal line emitting galaxies

Abstract Extreme coronal line emitters (ECLEs) are a rare class of galactic nuclei exhibiting unusually strong high-ionisation forbidden emission lines, and several ECLEs have been linked to tidal disruption events (TDEs). In this work, we compile and analyse optical spectra of 3...

Uneven TCR chain pairing constraints govern epitope recognition

Combinatorial pairing of independently recombined T cell receptor (TCR) α- and β-chains is central to diversifying the TCR repertoire. Although sequence motifs in one chain correlate with epitope recognition, the extent to which a single chain dictates specificity remains unclear...

Multi-stage single-cell atlas of a chordate non-embryonic development unveils dedifferentiating bud founder cells

Abstract Colonial tunicates are the only chordates capable of forming fully functional bodies from somatic tissues through non-embryonic development, or budding. In Botryllus schlosseri , budding produces new individuals (zooids) from a portion of the peribranchial epithelium of...

Test-retest reliability and associations of strength and functional outcome measures in adults with spinal muscular atrophy

Abstract Background Disease-modifying therapies for spinal muscular atrophy (SMA) require standardized follow-up to interpret treatment response. However, short-term changes may reflect measurement variability rather than true clinical change. We therefore assessed the test-retes...

Reproducible human reward imaging phenotypes exhibit differential sensitivity to dopamine D2 receptor antagonism

Abstract Human reward processing varies along cue-centric and outcome-centric axes, but a reproducible mechanistic account of individual variation in incentive salience attribution has been lacking. Using fMRI across five cohorts (N-total=1,251; N1=890; N2=245; N3=34; N4=48; N5=3...

Dry snow initialization and densification over the Greenland and Antarctic ice sheets in the ORCHIDEE land surface model

Abstract. Accurate modeling of the snowpack over ice sheets is essential for quantifying their surface mass balance contribution and their resulting impact on sea level rise. The snowpack evolution is largely governed by surface climate but also by internal processes such as dens...

A barycenter-based approach for the multi-model ensembling of subseasonal forecasts

Abstract. Ensemble forecasts and their combination are examined from the perspective of probability spaces. By treating ensemble forecasts as discrete probability distributions, multi-model ensemble (MME) forecasts are reformulated as barycenters of these distributions. We consid...