Sorbonne Université

Impact of phantom design on fetal radiation exposure assessment in pregnant women undergoing head and neck 6MV photon radiotherapy

Purpose This study investigates phantom-based methods for fetal radiation exposure assessment in photon external beam radiotherapy for a pregnant patient, using representative uterine locations as a conservative surrogate rather than direct measurements of fetal position or organ...

Resolving Peptide-Based Supramolecular Architecture Emerging at Reactive Copper/Water Interface

Abstract Understanding how molecular interactions evolve into ordered architectures at reactive solid/liquid interfaces remains a major challenge because surface reactivity can profoundly influence adsorption mechanisms. In such systems, multiple interfacial processes, including...

Space‐Based Observation of Decadal Variations of Ammonium Sulfate Aerosols Over Northern China

Abstract The concentrations of ammonium sulfate, an important component of secondary inorganic aerosols, have dropped substantially in the North China Plain (NCP) over the past decade. However, current understanding of its variations is limited by the small number of ground‐based...

The parent bodies of Ryugu and Ivuna formed before those of other carbonaceous chondrites

Most carbonaceous chondrite (CC) meteorites contain abundant chondrules, millimeter-scale spherical inclusions of previously molten material. Ivuna-type carbonaceous chondrites (CIs) do not contain chondrules, nor do samples of the carbonaceous asteroid Ryugu. CIs and Ryugu share...

Strongly coupled stimulated Brillouin amplification with flying focus

Damage to compression gratings poses a fundamental limit to chirped pulse amplification in high-power laser systems. Plasma-based compressors using strongly coupled stimulated Brillouin scattering (scSBS) offer a damage-free alternative, but their effectiveness has been hindered...

Use of cardiac magnetic resonance imaging after hospitalization for acute heart failure: insights from the French nationwide OFICA-2 cohort

Abstract Background Cardiac magnetic resonance (CMR) has a central role in the management of patients with acute heart failure (AHF), but timely access remains heterogeneous. We investigated real-world CMR use in patients hospitalized for AHF and its associations with demographic...

Cefepime exposure in prolonged or intermittent infusion in critically ill children

Aims Cefepime is commonly used in critically ill children for whom there is a high between‐subject variability. To reach the therapeutic pharmacokinetic (PK) target in critically ill patients, prolonged infusion of beta‐lactams seems to be the most efficient. The aim of this stud...

Performance of the iBox Prognostication System in African American Kidney Transplant Recipients

Background: The iBox is a validated prognostication system that predicts long-term death-censored graft loss in kidney transplant recipients, but its performance in the specific population of African American recipients has not been fully studied. Methods: We conducted a multicen...

Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in Multiple Myeloma: 30 Years in the Making

Immunomodulatory drugs (IMiDs) have fundamentally reshaped multiple myeloma therapy, extending survival and establishing durable backbones across induction, relapse, and maintenance. Cereblon's identification as a druggable E3 ligase substrate receptor created the mechanistic pat...

Characterization of Adsorption-Induced Deformation Behaviors in Microporous Dipodal Organosilane-Based Hybrid Silica Films

Abstract The distinctively high surface area of nanoporous solids (pore size <100 nm) makes them one of the most relevant classes of materials in adsorption-related applications. During vapor adsorption, stresses arising at the fluid–solid interface due to strong interactions wit...

Management of Acute Periodontal Conditions—The EFP S2k Level Clinical Practice Guideline

BACKGROUND: The European Federation of Periodontology (EFP) has developed Clinical Practice Guidelines (CPGs) for the treatment of periodontitis and for the management of peri-implant diseases. In accordance with the 2018 Classification, acute periodontal conditions are character...

Weak-Strong Uniqueness for the Landau Equation by a Relative Entropy Method

Abstract. We derive a weak-strong uniqueness and stability principle for the Landau equation in the soft potentials case (including Coulomb interactions). The distance between two solutions is measured by their relative entropy, which to our knowledge was never used before in sta...

Oveporexton for Narcolepsy Type 1 — Results from Two Phase 3 Trials

BACKGROUND: Narcolepsy type 1 is characterized by excessive daytime sleepiness, cataplexy, disrupted sleep, sleep paralysis, and hypnagogic or hypnopompic hallucinations. Oveporexton (TAK-861), an oral orexin receptor 2-selective agonist, reduced symptoms of narcolepsy type 1 in...

The added value of Med-CORDEX coupled high-resolution regional climate models in representing sea surface temperature and marine heatwaves in the Mediterranean Sea

Marine heatwaves (MHWs) pose significant threats to Mediterranean marine ecosystems and coastal economies, with frequency and severity projected to increase under future climate change. While Med-CORDEX fully-coupled Regional Climate System Models (RCSMs) offer enhanced resolutio...

Mean-Field Limit for Stochastic Control Problems under State Constraint

Abstract. We study the convergence problem of mean-field control theory in the presence of state constraints and nondegenerate idiosyncratic noise. Our main result is the convergence of the value functions associated to stochastic control problems for many interacting particles s...

Androgen receptor imprints satellite cell stemness and preserves their reservoir for lifelong regeneration and optimal repair

Skeletal muscle stem cells (MuSC) are the guardians of muscle regeneration, sustaining tissue integrity through a delicate balance of quiescence, activation, and lineage commitment. While numerous molecular cues have been implicated in regulating these processes, the influence of...

Convergence Analysis of a High-Order Multiscale Finite Element Method (MsFEM) for Stokes Flows in Heterogeneous Media

Abstract. An enriched nonconforming Multiscale Finite Element Method (MsFEM) to solve viscous incompressible flow problems in genuine heterogeneous or porous media was proposed in [Q. Feng, G. Allaire, and P. Omnes, Multiscale Model. Simul., 20 (2022), pp. 462–492]. The main feat...

Shedding light on the formation mechanisms of Islamic polychrome lusters: A Cu, Fe, Ag micro XANES study

Islamic luster is a ceramic glaze decoration exploiting the quantum-confined optical response of noble metallic nanoparticles to produce a colorful metallic and iridescent appearance. Upon firing, silver and copper initially present in an overpaint diffuse into the glaze and are...

Protocols on X-ray Absorption Spectroscopy Measurement and Interpretation

Abstract Understanding the local electronic and atomic structure of materials is central to modern physics, chemistry, materials science, and nanotechnology. X-ray absorption spectroscopy (XAS) provides element-specific insight into these local environments through core-level X-r...

Machine Learning and Molecular Simulations Reveal Mechanisms of ZIFs Polymorph Selection

metal-organic frameworks (MOFs) exhibit a remarkable degree of polymorphism. Because of their promising industrial applications, many research groups have investigated phase transitions, phase diagram and relative stability of these polymorphs. There is now wide consensus in the...