Sorbonne Université

A comparative study on the immobilization of organic-inorganic polyoxometalates hybrids onto gold electrodes: Direct versus indirect, covalent versus electrostatic grafting

Abstract We explored the conditions of the covalent grafting of organic-inorganic polyoxometalate hybrids onto gold using two basic reactions: the peptide-type coupling between a functionalized POM and a preformed organic self-assembled monolayer and the direct attachment of a th...

Beamstop-free small-angle X-ray scattering for multiscale structure measurement of high-energy-density plasma

The advent of free-electron lasers has enabled in-situ small-angle X-ray scattering (SAXS) measurements of laser-produced high-energy-density plasma at solid density, with nanometer- and femtosecond-scale resolution. Such plasmas generally exhibit gentle density gradients, which...

Polycyclic Aromatic Hydrocarbons in Kenyan Coral Reef Sediments: Distribution, Sources, and Equivalent Ecological Risks

This study evaluated the spatial distribution, source apportionment, and equivalent ecological risk of polycyclic aromatic hydrocarbons (PAHs) in 18 surface sediments across four Kenyan coral reef ecosystems (Malindi, Watamu, Kilifi, and Mombasa-Nyali). Total PAH concentrations (...

Sharper Bounds on the Required Fixed-Point Precision for Emulating Floating-Point Matrix Multiplication

Precision emulation algorithms, such as the Ozaki schemes, can leverage low-precision matrix multiply–accumulate to approximate the product \(AB\) , where \(A\) and \(B\) are high-precision floating-point matrices, via fixed-point arithmetic. A key difficulty of these approaches...

Cosmological Constraints from Full-scale Clustering and Galaxy–Galaxy Lensing with DESI DR1

Abstract We present constraints on cosmic structure growth from the analysis of galaxy clustering and galaxy–galaxy lensing with galaxies from the Dark Energy Spectroscopic Instrument (DESI) Data Release 1. Our analysis includes four samples drawn from the Bright Galaxy Survey (B...

Thermal Phase Behavior of PNIPAM-Based Hydrogels: Different Scenarios and Implications in Injectable Hydrogel Design

Poly(N-isopropylacrylamide) (PNIPAM)-based hydrogels are “smart” materials of great interest and demand, primarily in a variety of biomedical applications, due to their LCST close to physiological temperature. The basic biomedical applications of PNIPAM-based injectable hydrogels...

Paraneoplastic podocytopathies with nephrotic syndrome in solid cancers with C-Maf Inducing Protein expression

Abstract Background The main features of minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) associated with solid cancer (paraneoplastic podocytopathy with nephrotic syndrome, PPNS) remain poorly described. Methods In this French retrospective study, we fo...

Impact of a High‐Fiber, Fruitless Diet on the Gut Microbiome, and Health of Captive Orangutans

ABSTRACT Diet is a crucial factor in modulating the gut microbiome, and understanding these interactions in captive primates is essential for their health and welfare. This study assessed the impact of the transition to a high‐fiber, low‐sugar diet on the gut microbiome, behavior...

Crystallographic and Spectroscopic Evidence of High-Pressure Phase Transition of l -Histidine Methyl Ester Dihydrochloride

Abstract We investigate the dependence of the structural and vibrational properties of l-histidine methyl ester dihydrochloride (LHMED) on high-pressure conditions in the range of 0.0–8.2 GPa. Combining single-crystal X-ray diffraction (SCXRD) and Raman spectroscopy, we found a r...

Three-dimensional circulation controls on pollutant retention and mucilage accumulation in the sea of Marmara: A Lagrangian perspective

The Sea of Marmara is undergoing a severe marine pollution crisis driven by chronic nutrient enrichment and recurrent mucilage outbreaks. The physical mechanisms controlling transport, accumulation and persistence of pollutants and organic matter remain insufficiently resolved. H...

Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury

BackgroundThe preferred method of renal-replacement therapy for acute kidney injury in critically ill patients remains uncertain. MethodsIn this multicenter, open-label, noninferiority trial, we randomly assigned critically ill adults with acute kidney injury who had indications...

Sampled-Based Guided Quantum Walk: Non-variational quantum algorithm for combinatorial optimization

We introduce SamBa-GQW, a novel quantum algorithm for solving binary combinatorial optimization problems of arbitrary degree with no use of any classical optimizer. The algorithm is based on a continuous-time quantum walk on the solution space represented as a graph. The walker e...

Guidelines for Decisions to Withhold or Withdraw Life-Sustaining Treatments (LST) in Adult ICU

OBJECTIVE: The French Society of Anaesthesia and Intensive Care Medicine (Société française d'anesthésie et de réanimation, SFAR) and the French Society of Physical Medicine and Rehabilitation (Société Française de Médecine Physique et de Réadaptation (SOFMER)) aimed at providing...

Thermoelasticity of mixed-mode cracks in layered transversely isotropic half-spaces

A three-dimensional spectral formulation is developed for steady thermoelastic penny-shaped cracks embedded in layered transversely isotropic half-spaces, with arbitrary stacking sequences and mechanically compliant and thermally resistive interfaces. Its central feature is a com...

France’s Pesticide Load Index: Decreasing Ecotoxicity, Persistent Human Toxicity, Rising Concern For Environmental Fate

Pesticide use has strong adverse effect on biodiversity, ecosystem functioning and human health . Numerous policies have been proposed to reduce their use and associated risk but evaluations of changes in pesticide risk over time and space are still rare. Here, we evaluate tempor...

Serotype-independent inhibition of S. pneumoniae by SMiTE, a commensal-derived bacteriocin

ABSTRACT Streptococcus pneumoniae remains a leading cause of disease despite widespread vaccination, highlighting the need for serotype-independent strategies. We recently identified commensal streptococci that produce bacteriocins with anti-pneumococcal activity. Here, we evalua...

Joint Modeling of GD-1 and C-19 as Old Streams

Abstract DESI observational data for the GD-1 and C-19 streams are compared to stream simulations in an evolving multihalo potential of a Milky Way–like galaxy based on a cosmological Milky Way–like simulation. The number of subhalos decreases with time, and the subhalo-stream en...

Association between the site of emergency care and patient-centered outcomes in patients with cancer: rationale and design of the French COVER cohort

Patients living with cancer now account for a substantial and growing share of emergency department (ED) visits and carry a high burden of hospitalization and in-hospital death. Their acute presentations are frequently multifactorial - driven by disease progression, treatment tox...

Decoding multiway gravitational junctions in AdS in terms of holographic quantum maps

A bstract It has been shown that multiway junctions gluing n copies of locally AdS 3 spacetimes ( n ≥ 2) can be described by n − 1 strings obeying non-linear Nambu-Goto equations coupled by Monge-Ampère like terms. Here we study how such junctions along with their stringy degrees...

Autotaxin induces fibrosis in lamina cribrosa cells in glaucoma

Lysophosphatidic acid (LPA) and the enzyme that generates it, autotaxin, have been shown to play a role in fibrosis in the trabecular meshwork in glaucoma, contributing to increased intraocular pressure. We wished to investigate the role of LPA and autotaxin in fibrosis of the la...