Peking University

Evaluating the efficacy of pressure microcatheters for fractional flow reserve measurement in chronic thromboembolic pulmonary hypertension: a comparative study

This study aimed to compare the efficacy and procedural performance of pressure microcatheters and pressure guidewires for fractional flow reserve (FFR) measurement in patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing balloon pulmonary angioplasty (BP...

Discrepancy between knowledge and practice in folic acid supplementation for NTD prevention: a mixed-methods study of Chinese women

Abstract Background Neural tube defects (NTDs) remain a major preventable cause of congenital disability worldwide. Existing evidence suggests a persistent gap between awareness and actual supplementation behaviors among women of childbearing age. Aims To assess folic acid-relate...

Complementary feeding practices and acute respiratory infection symptoms among children aged 12–23 months in remote rural China: a cross-sectional analysis

Abstract Background Appropriate complementary feeding may contribute to protection against childhood respiratory infections, but evidence for specific feeding practices remains limited, particularly in rural China. We examined associations between WHO/UNICEF complementary feeding...

Tea Stewardship in Jingmai Mountain: A Practice‐Based and Cross‐Scalar Illustration of Ecological Citizenship in the Making

ABSTRACT The old tea forests of Jingmai Mountain in Yunnan, China, have been cultivated and maintained for centuries by indigenous Bulang and Dai communities through a unique ‘forest‐tea symbiosis’. We take this case as an entry point to examine a broader enquiry: how do a commun...

A Phosphazene‐Polyphenol Network Binder Enables Catalytic Polysulfide Conversion and Intrinsic Flame Retardancy for Practical Lithium‐Sulfur Batteries

ABSTRACT Practical deployment of lithium‐sulfur (Li‐S) batteries is severely hindered by polysulfide shuttling, structural degradation from severe cathode swelling, and flammability risks. Herein, we construct a cross‐linked macromolecular binder (HTP) by integrating bio‐derived...

Weak Superconducting Anisotropy in 4 H b ‐Nb 0.95 Ti 0.05 Se 2 With 1 T /1 H Heterostructure

ABSTRACT Heterostructures of layered transition metal dichalcogenide (TMD) exhibit rich physical properties by the combination of strong electronic correlation effects in 1 T layer and superconductivity in 1 H layer. But the limited number of bulk TMD materials with such heterost...

Purpose in life and exercise task behaviors: Evidence from a 10-week running task in college students

This study examined associations between purpose in life (PIL) and objective indicators of exercise task completion patterns among college students. Participants were 547 college students (Mean age = 19.71, 42.23% female) required to complete 63 km within 10 weeks for course cred...

Characterization of Thermal Recovery Activation in Fast Photochromic Flavoprotein Charge-Transfer Complexes

Abstract A promising fast, negative, red-absorbing photochromic system based on an intraprotein intermolecular charge transfer (CT) complex between a flavin cofactor and a substrate-analogue inhibitor MXA (methylthioacetate or methylselenoacetate; X = S, Se) within monomeric sarc...

Dual-Mode Photodetection and Neuromorphic Memory with PTCDI-C8/C8-BTBT Organic Heterojunctions

Abstract Merging optoelectronic sensing with synaptic emulation is critical for the progression of artificial intelligence. Herein, we report a bias-configurable dual-mode optoelectronic device engineered from a PTCDI-C8/C8-BTBT organic heterojunction, enabling a reversible trans...

MOCA: A Hierarchical Semantic-Enhanced Code Edit Framework for Multilingual Code Co-Evolution

Multilingual code co-evolution aims to propagate code edits across programming languages while preserving functional consistency, yet the task remains challenging in real-world repositories. Our motivating examples reveal two key challenges: (1) Existing models fail to infer the...

Sequencing Deoxyuracil at Single-Base Resolution via a Hydrazine Reagent-Induced U-to-A Transition

Abstract Uracil is a canonical base in RNA, yet its presence in DNA represents the most common non-canonical modification, with broad implications for diverse physiological processes. However, due to the lack of suitable analytical methods, the distribution and biological functio...

Macrophage pyroptosis drives luminal senescence and club-cell reprogramming in 5α-reductase inhibitor-treated prostatic hyperplasia

Abstract Benign prostatic hyperplasia (BPH) is a common age-associated disease whose prevalence rises sharply with advancing age. Therapeutic responses to 5α-reductase inhibitors (5-ARIs) in BPH are heterogeneous and may ultimately culminate in the need for surgery; however, the...

Reclassifying No Specific Molecular Profile Endometrial Cancer: A Narrative Review of Molecular Heterogeneity, Prognostic Refinement, and Clinical Management

Molecular classification has transformed the management of endometrial cancer (EC), yet the no specific molecular profile (NSMP) subtype remains a major challenge for precision oncology due to its substantial biological and clinical heterogeneity. This narrative review summarizes...

Satellite altimetry reveals heterogeneity in global flood peak timing and its shifts

Flood peak timing (FloPT) is a key indicator of hydrological responses to climate change. Yet global FloPT assessments is limited by sparse and uneven in-situ discharge observations. Here, we demonstrated the capability of satellite altimetry to estimate FloPT worldwide and prese...

MIMAS: An open-source microlens-array miniature microscope for accessible large-field cortical imaging in freely behaving mice

Large-scale cortical dynamics during natural behavior are difficult to measure because head-mounted imaging systems must balance field of view, spatial resolution, weight, and optical complexity. Existing wide-field miniature microscopes often rely on compound or custom-corrected...

A nuclear clock synchronized to 229Th

Abstract Atomic clocks have made time and frequency the most precisely measured quantities in physics, progressing from microwave standards that realize the SI second 1 to optical clocks with unprecedented precision 2 . A nuclear clock transfers the frequency reference from an el...

Emerging role of cGAS-STING in the pathogenesis of allergic diseases

The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway, classically recognized as a crucial cytosolic DNA-sensing mechanism in innate antiviral immunity, is now emerging as a pivotal regulator of sterile inflammation and immune dysregulation. Re...

A comparison of perioperative outcomes for da Vinci robotic-assisted, laparoscopic and open surgery in oncologic procedures: a systematic literature review and meta-analysis of evidence from China

The use of robot-assisted surgery (RAS) has increased markedly in China, but comparative evidence on its perioperative performance in cancer care is dispersed across specialties and study designs. This review synthesized Chinese evidence to examine the safety and effectiveness of...

Protocol for quantifying chromatin DNA replication by multiplex labeling and single-molecule localization microscopy

We present a protocol for imaging and quantifying chromatin DNA replication-associated signals in synchronized mammalian cells. We describe steps for cell-cycle enrichment, nucleoside analog-based metabolic labeling, and fluorescence detection. We then detail the procedure for du...

A Novel Teacher–Student Framework for Unsupervised Domain Adaptation in Multi-Perspective Road Pavement Damage Detection

Automated detection of road pavement damage is essential for ensuring road safety and preserving the integrity of transportation infrastructure. Traditional inspection methods often suffer from high labor demands, low time efficiency, substantial costs, and potential disruptions...