Peking University

Effects of human mobility on tuberculosis incidence in mainland China, 2010–2023: an ecological analysis and metapopulation modeling study

Human mobility plays an important role in the transmission of infectious diseases, yet its contribution to tuberculosis (TB) dynamics in China remains insufficiently quantified. We compiled a province-year panel for mainland China (2010–2023) to describe spatiotemporal trends usi...

Combining force and kinematic signals for human-computer interface: insights from cursor control by flexible pressure sensors

Cursor control becomes difficult in space-constrained environments, such as operating portable computers while wearing pressurised gloves. Flexible pressure sensorscan capture fingertip kinematic (centre of pressure, CoP) and force signals within confined spaces, offering a poten...

Autophagy-regulating bioactive nanoparticle alleviates MASH via gut–liver axis-mediated mitochondria/cAMP/GLP1 pathway

Chronic exposure of the liver to diverse insults can lead to metabolic dysfunction-associated steatohepatitis (MASH), a complex metabolic disorder characterized by hepatic steatosis and inflammation, often accompanied by progressive fibrosis, intestinal barrier dysfunction, and i...

Picard groups of quotient ring spectra

Abstract We develop tools to study Picard groups of quotients of ring spectra by a finitely generated ideal, which we use to show that , where is a Lubin–Tate theory and is an ideal generated by suitable powers of a regular sequence. We apply this to obtain spectral sequences com...

Mechano‐Electrical Coupling Scaffold Drives Bone Organoids Bioenergetic Reprogramming to Accelerate Bone Regeneration

ABSTRACT Critical‐sized bone defects remain a major clinical challenge in orthopedics and regenerative medicine. Bone organoid provided therapy potentials; however, current engineering strategies generally neglect the bioenergetic foundation and intrinsic mechano‐electrical coupl...

The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023

Background The cardiovascular-kidney-liver-metabolic (CKLM) framework represents the multi-organ interplay of systemic metabolic disorders that drive the global burden of cardiovascular diseases (CVD). Methods This study is a descriptive epidemiological analysis of the Global Bur...

Ultrasound Features as Adjunctive Predictors of Pathological Grade in Phyllodes Tumors of the Breast: An Imaging‐Pathology Correlation Study

ABSTRACT Background and Aim Phyllodes tumors of the breast are rare fibroepithelial neoplasms whose pathological classification remains challenging due to marked histological heterogeneity, often complicating clinical management decisions. This study investigated whether preopera...

Serial transthoracic echocardiography for hemodynamic monitoring and early warning of hypotension during elective cesarean delivery: a prospective observational study

Abstract BACKGROUND : Spinal anesthesia during cesarean delivery frequently causes maternal hypotension. Early detection of hemodynamic compromise before blood pressure decline could enable timely intervention. This study evaluates the use of serial transthoracic echocardiography...

Multi-objective and cross-scale inverse design of temperature-control materials via physics-constrained machine learning

Abstract Temperature-control materials, notably composite phase-change materials (CPCMs), show great potential for the thermal management of next-generation power electronics. However, the synergistic optimization of multiple performance metrics still relies heavily on Edisonian...

LAMDA: Leveraging Large Language Models for Better API Misuse Detection via Multi-Agent Collaboration

Modern software development heavily relies on reusing third-party and internal Application Programming Interfaces (APIs). However, API misuses occur frequently, leading to program crashes, security vulnerabilities, and other unexpected behaviors. To detect API misuse, many existi...

Transfer Learning of CATE with Kernel Ridge Regression

The proliferation of data has sparked significant interest in leveraging findings from one study to estimate treatment effects in a different target population without direct outcome observations. However, the transfer learning process is frequently hindered by substantial covari...

Protocol for the ACTIVE trial: a multicentre, open-label, cluster-randomized controlled trial of a quality improvement programme for older adults with hip fracture in resource-limited hospitals in China

Aims The primary aim of the Action on Hip Fracture Management Quality Improvement (ACTIVE) trial is to evaluate whether a context-tailored quality improvement programme improves health-related quality of life at 120 days after hospital admission, among adults aged 65 years or old...

Coordination Engineering of Cobalt Single-Atom Catalysts for Periodate Activation with Regulated Reactive-Species Production toward Emerging Contaminants Degradation

Abstract Fenton-like reaction of heterogeneous periodate (PI) activation exhibits high efficiency for emerging contaminants degradation due to the production of iodine-centered radicals, and single-atom metal catalysts demonstrate high activity. However, precisely controlling the...

A global dataset of forest disturbance regimes derived from satellite biomass observations

Abstract. Forests play a central role in the global carbon cycle by serving as critical carbon sinks for atmospheric CO2. Yet, the stability and continued capacity of these sinks are increasingly threatened by a growing number of disturbances. Accurately representing the stochast...

Remimazolam vs. propofol sedation for video laryngoscopy in cervical spondylosis patients with suspected difficult laryngoscopy: a randomized controlled trial

Abstract Background This study aimed to explore the efficacy and safety of remimazolam vs. propofol for sedation during video laryngoscopy in cervical spondylosis patients with suspected difficult laryngoscopy. Methods In this single-center, prospective, randomized controlled stu...

Comparison of Birth Weight Outcomes Between Donor Sperm and Partner Sperm in Fresh Embryo Transfer Cycles: A Single‐Center Clinical Cohort Study

ABSTRACT Background Previous studies have found no significant difference in birth weight between donor sperm and partner sperm, and some studies have found that donor sperm is more likely to lead to small for gestational age (SGA). Objective Does the use of donor sperm affect th...

Level of education is associated with risk of kidney diseases in middle-aged and elderly adults: evidence from the CHARLS

Although numerous studies have indicated that various socioeconomic factors influence the risk of developing kidney disease, clinical evidence regarding the relationship between level of education (LoE) and the risk of kidney disease remains insufficient. This study aims to evalu...

Performance guarantees of light-cone variational quantum algorithms for the maximum cut problem

Abstract Variational quantum algorithms (VQAs) are promising to demonstrate the advantage of quantum computing over classical computing in practical applications, such as the maximum cut (MaxCut) problem. However, current VQAs such as the quantum approximate optimization algorith...

Gate-imprinted memory and light-induced erasure of superconductivity at KTaO3-based interfaces

Realizing non-volatile control of superconductivity is a key step toward integrating memory and quantum functionality in future information technologies. KTaO₃-based heterostructures uniquely host interfacial two-dimensional superconductivity and quantum paraelectric lattice back...

Fine-tuning an ECG foundation model to predict coronary CT angiography outcomes

<title>Abstract</title> Coronary artery disease (CAD) remains a major global health burden. Accurate identification of the culprit vessel and assessment of stenosis severity are essential for guiding individualized therapy. Although coronary CT angiography (CCTA) is the first-lin...