Nanchang University

Transposable elements as evolutionary catalysts of ant macrodiversity

Transposable elements (TEs) are key contributors to genome evolution, yet their macroevolutionary roles in adaptive radiations remain poorly understood, as high-quality genomic resources at sufficient phylogenetic breadth and appropriate comparative methods have been lacking. Her...

Genetic transformation of Pinus elliottii: Association of SPX3 with coordinated nitrogen-phosphorus metabolism and antioxidant defense

The lengthy breeding cycle of Pinus elliottii Engelm., an economically important conifer widely cultivated in southern China, and the inherently low transformation efficiency of conifers present major obstacles to genetic improvement. To address these challenges, an Agrobacterium...

Hepatitis B virus infection and lung cancer risk: evidence from meta-analysis, Mendelian randomization, and integrative transcriptomic analyses

Epidemiological studies have suggested an association between hepatitis B virus (HBV) infection and lung cancer, but the potential causal relationship and shared molecular features remain unclear. This study integrated epidemiological, genetic, and transcriptomic evidence to inve...

Construction of Isonicotinic Acid Derivative-Based Hydrogen-Bonded Organic Frameworks for Selective Detection and Adsorption of Radionuclide Th(IV)

Abstract Th(IV) poses severe radioactive hazards once released into the environment due to its long half-life and potential bioaccumulation. Therefore, the development of multifunctional materials capable of simultaneous detection and removal of Th(IV) becomes an urgent research...

Design and fabrication of a freeform optical engine for full-color geometric waveguide augmented reality glasses

One-dimensional (1D) geometric waveguide displays are well suited for full-color augmented reality (AR) glasses because they provide higher optical efficiency and require lower source radiance than two-dimensional pupil-expanding architectures. However, the highly asymmetric shap...

CEO political organizational experience and firm productivity

Purpose Drawing on upper echelons and imprinting theories, we examine whether chief executive officers’ (CEOs') political organizational experience is associated with firms' subsequent total factor productivity (TFP). Design/methodology/approach We conduct panel data analyses to...

Moringa oleifera Leaf-Derived Exosome-Like Nanoparticles Target Macrophage Senescence to Drive M2 Polarisation and Attenuate Alveolar Bone Loss

Background Periodontitis is a chronic inflammatory disease characterised by progressive alveolar bone loss. Macrophages play a pivotal role in coupling inflammation to disrupted bone metabolism, and their dysregulation is a key driver of bone resorption. However, precise therapeu...

Rimegepant for vestibular and cochlear symptoms associated with vertigo in a real-world retrospective study

Vertigo commonly co-occurs with cochlear symptoms, yet evidence for calcitonin gene-related peptide (CGRP) receptor antagonists across audiovestibular disorders remains limited. We retrospectively evaluated 54 adults with vertigo who received rimegepant 75 mg daily or every other...

Research Progress on Small-Molecule Inhibitors Targeting Salt-Induced Kinases

Abstract As prominent members of the AMPK family, salt-induced kinases (SIKs) play pivotal roles in regulating cellular metabolism, immune responses, and the tumor microenvironment. Aberrant SIK expression is closely linked to oncogenesis, metabolic disorders, and inflammatory di...

Pore-Scale Investigation of Convective Drying in Porous Media: Effects of Mixed Wettability and Structural Heterogeneity

Abstract How spatially organized mixed wettability controls pore-scale interface recession and liquid replenishment during convective drying remains insufficiently understood. This study investigates this process using an established multicomponent pseudopotential lattice Boltzma...

Short-Range Mass Transfer in Core–Shell Catalysts Suppresses Radical Self-Quenching for Efficient Water Purification

Abstract Fenton-like reactions hold considerable promise for organic wastewater treatment. However, their practical application remains limited by the difficulty of synthesizing the catalyst’s local structure in a controlled manner through a sustainable route. Herein, a coordinat...

Triglyceride-glucose-sarcopenia index and risk of cardiovascular diseases in multinational prospective cohorts

Abstract Background Muscle tissue dictates insulin-driven glucose uptake; muscle dysfunction paired with insulin resistance can trigger a compound cardiometabolic failure. However, whether this dual pathology confers incremental long-term cardiovascular risk stratification is yet...

Construction of an m5Cscore based on m5C modification patterns to predict prognosis and personalized treatment outcomes in breast cancer

Accumulating evidence links 5-methylcytosine (m 5 C) modifications to tumor progression and gene regulation. This study aimed to systematically characterize m 5 C modification patterns in breast cancer, elucidate their associations with prognosis and tumor heterogeneity, and prov...

Bifidobacterium animalis subsp. lactis delays epithelial ovarian cancer progression by secreting acetate and regulating the NRF2–HO-1–ferroptosis pathway

Recent advances have highlighted the anti-tumour effects exerted by the gut microbiota and its derived metabolites through modulation of ferroptosis; however, their role in epithelial ovarian cancer (EOC) has not been fully explored. Based on qPCR analysis and previous 16S rRNA s...

Albumin-based nutritional-inflammatory indices and prognosis in critically ill patients with acute myocardial infarction: a MIMIC-IV cohort study

This study investigated the associations between 12 albumin-based nutritional–inflammatory indices and adverse outcomes in critically ill patients with acute myocardial infarction and compared their prognostic performance. A retrospective cohort study was conducted using the MIMI...

Associations of structured and unstructured physical activity time in kindergarten with physical fitness in preschoolers: an isotemporal substitution and time threshold analysis

This cross-sectional study aimed to examine how reallocating time across different types of activities is associated with preschoolers’ physical fitness and to identify potential time thresholds that could inform kindergarten activity planning. A total of 337 Chinese preschoolers...

Extrachromosomal DNA as a platform for epigenetic reprogramming in cancer

Extrachromosomal DNA (ecDNA) has emerged as a major contributor to cancer aggressiveness, yet its role extends far beyond its classical definition as a vehicle for oncogene amplification. Recent studies indicate that ecDNA functions as a dynamic regulatory platform that reshapes...

Endocrine adverse events related to immune checkpoint inhibitors in gastric cancer

This study aimed to systematically assess the endocrine adverse reactions associated with Immune checkpoint inhibitors (ICIs) in the treatment of gastric cancer. Data from the FDA Adverse Event Reporting System (FAERS) spanning from Q1 2013 to Q3 2024 were analyzed. The associati...

Diffusion reconstruction with validity masks and measurement consistency for low-frame structured illumination microscopy

Reducing the raw-frame budget of structured illumination microscopy (SIM) lowers exposure burden but weakens orientation–phase diversity and increases sensitivity to noise and model mismatch. We present acquisition-aware physics-guided diffusion for SIM (APD-SIM), which combines...

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

Abstract Postoperative recurrence remains a critical challenge in cancer management, necessitating innovative strategies to reshape the tumor microenvironment (TME) and enhance immune surveillance. This review highlights nanomedicine‐driven breakthroughs in postoperative immunoth...