Keio University

Development of an interprofessional education program for aspiration pneumonia care: an action research study

INTRODUCTION/AIM: Aspiration pneumonia has evolved, with demographics shifting to predominantly frail older adults. However, despite the high healthcare impact, there is no established guideline or curriculum for the education and training of healthcare professionals in managing...

Gut microbial and metabolic biomarkers for early-onset colorectal cancer

Early-onset colorectal cancer (EO-CRC) is a growing global health challenge with poorly understood etiology. While gut microbiota and metabolites are implicated in colorectal carcinogenesis, EO-CRC-associated signatures remain poorly characterized. This study presents the first l...

Attention‐Based Spatial–Temporal Model for the Entire Indoor Space Temperature Estimation

This study proposes a novel attention‐based spatial–temporal model for indoor temperature estimation, which integrates positional encoding and an attention mechanism with a fully connected neural network. By jointly capturing temporal dynamics and spatial correlations, the model...

Patient acceptance of regenerative medicine trial designs for spinal cord injury in a nationwide web-based survey in Japan

Abstract Patient acceptance of regenerative medicine trial designs in spinal cord injury (SCI) remains poorly understood. We conducted a nationwide, anonymous, web-based survey of individuals with SCI in Japan to assess willingness to participate in hypothetical regenerative medi...

Cross-disease immunological comparison reveals shared systemic immune activation across the broader spondyloarthritis spectrum

To perform cross-disease immunological comparison across the broader spondyloarthritis (SpA) spectrum and examine their association with disease activity. We analyzed 111 patients with active broader SpA spectrum (ankylosing spondylitis, inflammatory bowel disease–associated SpA,...

Genomic resources of Ascidiella aspersa and comparative analysis across tunicates reveal class-level features and evolutionary diversification

Ascidiella aspersa is an invasive tunicate and one of the closest relatives of vertebrates. Despite its ecological nuisance, A. aspersa is anticipated to be a valuable model organism for developmental studies due to its remarkably transparent embryos. However, annotated genome as...