Institution
Keio University
Recent research
- Health & MedicineOpen access
We conducted an anonymous online survey to clarify awareness, knowledge, and utilization of Japanese physical activity (PA) guidelines among certified Health Fitness Programmers who are specialists in exercise guidance for health promotion. Responses were obtained from 415 partic...
- Health & MedicineOpen access
Abstract Background Surgery and chemoradiotherapy (CRT) are standard options for clinical stage I esophageal squamous cell carcinoma (ESCC). JCOG0502, a multicenter, non-randomized, parallel-group comparison, demonstrated the non-inferiority of definitive CRT compared with surger...
- Climate & Environment
The aim of this research is to identify the radiological protection problems after the Fukushima accident from the citizens’ perspective and to clarify the major points which should be included in the revised General Recommendations. As research methods, both qualitative and quan...
- Society & EconomicsOpen access
Purpose This study presents a learning and unlearning journey shared by critically oriented researchers based at Japanese universities and development practitioners from the Japan International Cooperation Agency (JICA), who collaboratively reflected on educational development fr...
- Engineering & TechnologyOpen access
Machine Learning of Temperature‐Dependent Chemical Kinetics Using Parallel Droplet Microreactors
Temperature is a fundamental regulator of chemical and biochemical kinetics, yet capturing nonlinear thermal effects directly from experimental data remains a major challenge due to limited throughput and model flexibility. Recent advances in machine learning have enabled flexibl...
- Climate & EnvironmentOpen access
Abstract In this study, the blast-wave formation and mushroom-cloud development associated with the Nagasaki atomic bombing were numerically investigated to construct initial conditions for subsequent meteorological simulations of “black rain.” To evaluate the three-dimensional t...
- AI & ComputingOpen access
MIBO-Education Protocol Package v1.0
MIBO-Education Protocol Package v1.0 provides the frozen scientific specification for MIBO-Education, a longitudinal observatory of educational behavior in general-purpose generative-AI services and an official Satellite of the Machine Information Behavioral Observatory (MIBO). T...
- BiologyOpen access
Abstract Topic Esophageal Cancer: New Diagnostic Modalities (Including PET, PET-CT, New Tracers) Background In the perioperative management of esophageal squamous cell carcinoma (ESCC), the accuracy of conventional modalities such as computed tomography and esophagogastroduodenos...
- AI & ComputingOpen access
MIBO-Education Protocol Package v1.0
MIBO-Education Protocol Package v1.0 provides the frozen scientific specification for MIBO-Education, a longitudinal observatory of educational behavior in general-purpose generative-AI services and an official Satellite of the Machine Information Behavioral Observatory (MIBO). T...
- Society & EconomicsOpen access
Half the Capital Stock, One Premise: Japan's ¥1 Quadrillion of Implicit Power-System Credit
Productivity Research Notes (PRN Series), No. 2619 Reliable electricity at economically viable prices underpins long-lived capital. Using a bottom-up classification of more than 170 asset categories, this note estimates Japan's electricity-dependent capital stock at ¥1,000.8 tril...
- Society & EconomicsOpen access
Half the Capital Stock, One Premise: Japan's ¥1 Quadrillion of Implicit Power-System Credit
Productivity Research Notes (PRN Series), No. 2619 Reliable electricity at economically viable prices underpins long-lived capital. Using a bottom-up classification of more than 170 asset categories, this note estimates Japan's electricity-dependent capital stock at ¥1,000.8 tril...
- BiologyOpen access
Cryo-EM structure of the bicarbonate receptor GPR30
G-protein-coupled receptor 30 (GPR30) is a bicarbonate receptor that plays a vital role in cellular responses to extracellular pH and ion homeostasis. Despite its significance, the mechanisms by which GPR30 interacts with bicarbonate ions remain elusive. There is no consensus on...
- Engineering & Technology
Thermal management remains one of the critical challenges in the advancement of rotating detonation engine (RDE) technology for practical propulsion applications. To facilitate progress in this field, this study investigates the use of gaseous film cooling via axial injectors, ai...
- Health & Medicine
ABSTRACT Aim Alpha‐fetoprotein (AFP) and des‐gamma‐carboxy prothrombin (DCP) are widely used tumor markers for hepatocellular carcinoma (HCC); however, their relative prognostic significance in early‐stage disease remains unclear. This study aimed to compare the prognostic impact...
- BiologyOpen access
Trajectory elevation in reach-to-grasp movements under increased arm weight and repeated trials
This study examined how three-dimensional upper-limb movement trajectories are modulated by changes in gravitational load. We hypothesized that individuals adopt a trajectory elevation strategy in reach-to-grasp movements performed on a desk to compensate for increased movement v...
- Engineering & TechnologyOpen access
ActivAsk: Free-Energy-Guided Clarification for Robotic Grasping Under Ambiguous Instructions
Service robots often receive natural language instructions in changing workspaces where multiple visible objects may match one description. Relying on detector confidence, random selection, or direct vision–language model (VLM) prediction can lead to a wrong action. This paper pr...
- AI & ComputingOpen access
Fast robust additive models using gamma-divergence
Abstract Additive models offer a flexible framework for modeling nonlinear relationships between predictors and a continuous response variable, where nonparametric terms are commonly modeled via penalized splines. However, such models can be sensitive to outliers, leading to pote...
- Health & MedicineOpen access
Participation of pharmacists during physicians’ home visits is effective in home healthcare. However, substantial practical barriers exist in regions where medical resources are unevenly distributed. This study sought to clarify the effectiveness and limitations of a hybrid onlin...
- Health & MedicineOpen access
従来，根治切除不能なRAI不応再発転移分化型甲状腺癌に対して使用されてきた多標的チロシンキナーゼ阻害薬のレンバチニブは，出血リスクから大血管浸潤が疑われる例では使用回避が望まれるが，BRAF/MEK阻害薬は明確な禁忌は示されていない。今回われわれは，総頸動脈を全周性に取り囲む甲状腺乳頭癌再...
- Health & MedicineOpen access
Proton pump inhibitors (PPIs) are classified as potentially inappropriate medications for older adults. Indiscriminate long-term use of PPIs after symptom resolution (indiscriminate PPIs) may increase the risk of adverse events and healthcare costs, emphasizing the need for appro...