Jinan University

The effects of different prone positioning angles on cardiopulmonary function in children after congenital heart disease surgery: a randomized controlled trial

To evaluate the effects of different head-elevated prone positioning angles on oxygenation, respiratory mechanics, hemodynamics, and enteral nutrition tolerance in children after congenital heart disease（CHD）surgery, and to determine the optimal intervention angle. In this rand...

Health utility and equity-related correlates among adults with rare diseases in Foshan City, China: an exploratory cross-sectional study using the EQ-5D-5L

Rare diseases (RDs) are associated with substantial and potentially avoidable health inequities related to chronic disability, social disadvantage, and high non-medical costs. Evidence on health-related quality of life (HRQoL) among adults living with RDs in China remains scarce,...

Physical and mental health conditions in men who have sex with men: a global umbrella review of meta-analyses

Men who have sex with men (MSM) face a disproportionate burden of health problems. Prior syntheses among MSM have not comprehensively addressed key areas such as non-communicable diseases, mental health, and comorbidities. This umbrella review aimed to synthesize and evaluate met...

Photo-pyroelectric effect induced by interfacial symmetry breaking in van der Waals contacts for self-powered dual-mode photodetection

The pyroelectric effect from spontaneous polarization offers significant potential for self-powered optoelectronics. However, achieving the macroscopically measurable pyroelectric response remains challenging. Herein, we introduce the pronounced photo-pyroelectric effect in a mac...

The Visibility Paradox: A Socio-Technical Systems Perspective on the Empowering and Surveillance Effects of Production Data Transparency in Smart Manufacturing

Production data transparency in smart manufacturing simultaneously enhances and impairs employee performance across organizational contexts. Existing research has not resolved this theoretical contradiction. Drawing on socio-technical systems theory, cognitive appraisal theory, a...

Identification of a novel small-molecule modulator targeting SNX10 to inhibit osteoclastic bone resorption

Current antiresorptive therapies reduce bone loss by eliminating osteoclasts or inhibiting their formation. However, these approaches could disrupt osteoclast-osteoblast communication and cause serious complications with long-term usage. There is a need for developing new therapi...

Spatially Controlled Imaging of Proteases in Acidic Extracellular Milieu of Lesions Using DNA‐Peptide‐PNA Hybrid Probes

ABSTRACT In situ detection of proteases has been extensively exploited for diverse biomedical applications; however, spatially controlled amplified imaging of extracellular proteases at diseased sites remains a significant challenge. Here, we report the design of DNA‐peptide‐PNA...

Smart city policy and firm digitalization: evidence from MD&A disclosures

Purpose This study aims to examine whether smart city policies influence corporate digital transformation. Using China’s National Smart City Pilot Project as a quasi-natural experiment, we investigate if smart city designation affects firms’ digitalization levels as reflected in...

Stable High‐Rate Sodium Metal Batteries at Room and Low Temperature Enabled by Mixed Ion/Electron‐Conducting Interphase Engineering

Sodium metal batteries (SMBs) with high energy density showed great promise for various applications, but they are plagued by uneven and low‐reversibility sodium plating/stripping, particularly when fast‐charging capability at subzero temperatures is pursued. Here, we present a f...

Crystalline Mate Assists Structural Elucidation and Offline LC‐SCXRD Analysis of Flavonoid Glycosides via Synergistic π–π Stacking and C–H···O Interactions

Single-crystal X-ray diffraction (SCXRD) is a key technique for the structural determination of organic molecules. However, natural flavonoid glycosides are difficult to crystallize due to their large volume, flexible glycosidic bonds, and limited solubility. Herein, a novel meth...

Reconfigurable multibeam engineering of Marangoni convection for programmable optofluidic steering

Optofluidic manipulation provides a powerful route for guiding micro- and nanoparticles, yet conventional light-induced flow systems often suffer from limited controllability, unstable flow patterns, and poor reconfigurability. Here, we demonstrate programmable optofluidic steeri...

Programmable RNA targeting with clustered regularly interspaced short palindromic repeats (CRISPR) effector Cas7-11 in zebrafish embryos and mammalian cells

<title>Abstract</title> <bold>Background</bold> The CRISPR/Cas7-11 system is a recently characterized RNA editing tool that exhibits low toxicity, minimal off-target effects, and reduced collateral RNA cleavage compared with existing methods. Although zebrafish and human embryoni...

Uncertainty-inspired open-set model for identifying infantile fundus abnormalities

Accurate and safe identification of infantile fundus abnormalities is critical for large-scale screening, yet remains challenging because of heterogeneous disease presentations and overconfident predictions by conventional artificial intelligence (AI) models. In this study, we ai...

Associations of early-life exposure to PM2.5 mass and its components with childhood anemia: A cross-sectional study in China, India, and Africa

Childhood anemia remains a major public health concern, but evidence regarding the associations of early-life exposure to PM 2.5 mass and its components with childhood anemia across regions remains limited. We conducted a cross-sectional study of 449,894 children under 5 years fr...

Role of Life’s Essential 8 in the association of night shift work with cardiovascular disease and mortality: a prospective cohort study of UK Biobank participants

Background: Night shift work is linked to higher risks of cardiovascular disease (CVD) and mortality, but mechanisms remain unclear. Lifestyle, captured by the American Heart Association's Life's Essential 8 (LE8), may act as a modifiable mediator. We aimed to examine the associa...

Identification of prognostic genes for hepatocellular carcinoma based on hepatocyte and ketone body metabolism using integrated bulk and single cell RNA sequencing

<title>Abstract</title> Background The precise role of ketone body (KB) metabolism and the underlying cellular mechanisms in hepatocellular carcinoma (HCC) remain unclear. This study aimed to identify and mechanistically explore KB metabolism-related prognostic genes in HCC. Meth...

Artificial intelligence and liquidation: Reality, destiny and fantasy

Abstract Artificial intelligence (AI) is increasingly reshaping the administration of corporate liquidation. Beyond its established role in financial prediction and data analytics, AI is now assisting insolvency practitioners in identifying the onset of financial distress, managi...

Action chunking transformer-based imitation learning with dynamic programming optimization for low-cost robotic assembly tasks

Nowadays, many studies focus on using AI tools to improve the performance of manipulators in fields such as assembly. One popular approach is the Action Chunking Transformer (ACT), which enables robots to execute assembly tasks more efficiently. However, this method still faces c...

Heart rate control by listening to light

The auditory-cardiac interplay enables sound perception to modulate cardiac rhythm and homeostasis. However, its underlying regulatory mechanism and therapeutic potential remain largely underexplored, due to fundamental limitations in acoustic stimulation precision. Here we prese...

A gut microbiome‐lipid axis in early pregnancy is associated with metabolic dysregulation and diabetes risk

Abstract Gestational diabetes mellitus (GDM) reflects metabolic dysregulation that becomes clinically apparent during pregnancy and shares key pathophysiological features with broader forms of diabetes. Gut microbiome‐host metabolic interactions may contribute to this process, ye...