Istanbul University

FastSurfer-Based Brain Morphometry and Machine-Learning Classification Across the Alzheimer’s Disease Spectrum

Background: This study aimed to quantitatively assess structural changes in the hippocampus, amygdala, entorhinal cortex, lateral ventricles, precuneus, and posterior cingulate using deep-learning-based FastSurfer morphometry and evaluate their contribution to classification acro...

Whole-Life Carbon Governance in Building Regulation: Türkiye and Selected European Regulatory Pathways

Whole-life carbon (WLC) governance is increasingly important to the decarbonization of the built environment, yet its incorporation into building regulation differs across jurisdictions and instrument types. This study examines how WLC governance is represented in Türkiye’s build...

Epidural Electrical Stimulation Within an Integrated Rehabilitation Pathway for Traumatic Cervical Spinal Cord Injury: Safety and 12-Month Functional Outcomes

Background/Objectives: Epidural electrical stimulation (EES) is an investigational, off-label neuromodulation strategy used adjunctively with rehabilitation in chronic spinal cord injury (SCI), but safety and longitudinal functional data specific to traumatic cervical SCI remain...

Adenomyosis and Uterine Fibroids: Two Distinct Yet Overlapping Clinical Entities

Adenomyosis and uterine fibroids are among the most common benign uterine disorders in women of reproductive age and represent major causes of abnormal uterine bleeding, pelvic pain, and infertility. Despite their distinct histopathological features, they frequently coexist and s...

The effect of systemic inflammation on locoregional colon cancer recurrence

Curative-intent treatment fails to prevent recurrence in a significant proportion of patients with locoregional colon cancer. Systemic inflammation plays a critical role in colorectal cancer progression. We evaluated the association between preoperative systemic inflammatory mark...

Association between cervical sagittal alignment, neck awareness, and disability in chronic neck pain: The possible role of probable sleep bruxism

Background Chronic neck pain (CNP) is a major cause of disability. Cervical sagittal alignment, neck awareness, and probable sleep bruxism may influence symptom burden. Methods This cross-sectional study included 76 patients (18–60 years) with CNP. Probable sleep bruxism was clas...

Joint XMM-Newton and NuSTAR Observations of Type I X-ray Bursts from the Dipping Low-Mass X-ray Binary 4U 1323–62

Abstract In this study, we report partly simultaneous XMM-Newton and NuSTAR observations of the bursting, dipping low mass X-ray binary, 4U 1323–62 obtained in 2024. 4U 1323–62 is one of the well-known persistent bursters, with bursts occurring roughly every three hours. It is al...

Chitosan–Orientin Nanoparticles Attenuate Hypoxia-Induced Pulmonary Inflammation in Rats

Background: Hypoxia triggers pulmonary inflammation and oxidative stress, leading to endothelial dysfunction, apoptosis and lung injury. Although the flavonoid orientin exhibits potent antioxidant and anti-inflammatory properties, its pharmacokinetic behavior remains incompletely...

Artificial Intelligence (AI) for Global Diplomacy and Sustainable Global Governance: A Systematic Literature Review

Artificial intelligence (AI), as a key component of contemporary digital technologies, has emerged as a transformative technology across various sectors, including international relations and diplomacy. As AI technologies continue to evolve within the broader digital transformati...

Explainable Machine Learning for Methylene Blue Removal Under Irradiation: Assessing Nominal Cu-Loading in AC@NiO

The time-dependent removal performance under irradiation of activated-carbon-supported nickel oxide (AC@NiO) samples containing nominal Cu-loadings of 0%, 3%, 5%, 7.5%, and 10% was examined using experimental concentration data and an explainable machine-learning (ML) framework....

Pharmacokinetics of meloxicam following intramuscular, subcutaneous, and oral administration in white storks (Ciconia ciconia)

Abstract Background Meloxicam (MLX) is a preferential cyclooxygenase-2 inhibitor widely used in avian medicine as an anti-inflammatory agent. Despite marked interspecific variability in avian drug disposition, no pharmacokinetic data are available for MLX in the white stork ( Cic...

Comparison of the Effects of Kinesio Taping and Foam Roller Exercises in Individuals with Non-Specific Chronic Low Back Pain

Background/Objectives: Non-specific chronic low back pain is a prevalent musculoskeletal disorder that impairs flexibility, sleep quality, functional capacity, and quality of life. Conservative treatments such as Kinesio taping and foam roller exercises are widely used, yet compa...

Breastfeeding Myths Among Nursing and Midwifery Students: A Descriptive Cross-Sectional Study

Background: Breastfeeding myths held by healthcare professionals may affect the accuracy and consistency of counseling provided to women and families. This study evaluated nursing and midwifery students’ breastfeeding myths and associated factors. Methods: This descriptive, cross...

Early implant stability in reconstructed alveolar bone supported by iliac crest grafts using bone-enhancing drills: a retrospective clinical study

Autogenous iliac crest grafts are widely used for reconstruction of extensive alveolar defects because of their osteogenic potential and ability to support implant placement. However, limited evidence exists regarding early implant stability patterns in reconstructed alveolar bon...

Vitamin B6 Modifies Tau-Induced Cellular Stress- and Proteostasis-Related Responses

Abnormal tau expression is associated with disruption of cellular homeostasis and activation of stress-response pathways. However, the effects of vitamin B6 on cellular stress responses associated with tau expression remain unclear. In this study, the influence of vitamin B6 on o...

Quality and engagement of Instagram content related to mouthguard use in the prevention of sports-related dental trauma: a cross-sectional content analysis

Social media platforms have become major sources of health-related information, particularly among children, adolescents, and their caregivers. Instagram, one of the most widely used platforms, hosts a large volume of user-generated content on preventive health topics. Mouthguard...

When Language Excludes: Linguistic Ostracism, Psychological Ownership, and Destructive Voice Behavior

ABSTRACT Workforces are becoming increasingly multilingual, yet relatively little is known about how language‐based exclusion shapes employee behavior. Drawing on social exchange theory, we examine how linguistic ostracism, a subtle form of workplace exclusion, undermines employe...

Speckle aware attention and multi scale pooling for robust breast ultrasound lesion classification across multiple benchmarks

Breast ultrasound (BUS) is widely used for lesion assessment, yet automatic benign–malignant classification remains challenging owing to speckle noise, weak boundaries, and cross-scanner heterogeneity. We propose SUA-Net, a compact framework that augments an EfficientNet-B0 backb...

Effects of bone-quality configuration, effective peri-implant interface stiffness, and loading configuration on stress distribution in an ultrashort implant system: a three-dimensional finite element analysis

Abstract Background Ultrashort implants may reduce vertical augmentation needs when residual bone height is limited, but reduced intraosseous support may increase sensitivity to eccentric loading. This full-factorial study evaluated the effects of bone-quality configuration, effe...

Comparison of Direct Oral Anticoagulants and Low-Molecular-Weight Heparins in Cancer Patients with Nonvalvular Atrial Fibrillation: Insights from a Single-Center Experience

BACKGROUND: Atrial fibrillation (AF) is frequently encountered in patients with cancer and poses challenges for anticoagulant management. The present study was conducted to compare clinical outcomes associated with direct oral anticoagulants (DOACs) and low-molecular-weight hepar...