Istanbul University

Investigation of arterial blood flow changes according to compression level in a practical blood flow restriction training method: A cross-sectional experimental study

Background Blood flow restriction (BFR) training is used to partially restrict limb blood flow during exercise. Practical blood flow restriction (pBFR) applications often rely on subjective pressure scales; however, the extent to which perceived compression levels influence arter...

Between precarity and pride: negotiating masculinity and migration in Turkey’s platform economy

Purpose This study examines how human–technology interrelations in platform work shape male migrant workers’ experiences of inclusion and exclusion in Turkey, and how these experiences intersect with masculinity, responsibility and everyday solidarity under precarious conditions....

Giant Plexiform Neurofibroma in Neurofibromatosis Type 1

This case report describes a pendulous hyperpigmented lesion with a ridged bag-of-worms surface, multiple café-au-lait macules, and axillary freckling across the patient’s trunk and arm.

Heart sound classification using machine learning approaches based on mel-frequency cepstrum coefficients (MFCCs) and statistical features

Heart sounds provide a valuable non-invasive source of information for the early detection of cardiac abnormalities. However, reliably distinguishing normal from abnormal heart sounds remains challenging in routine clinical practice because interpretation depends strongly on expe...

From Feuilleton Turc to geopolitics: how Tunisian audiences consume and interpret Turkish television dramas

Turkish television series and cinema have emerged as significant instruments of cultural projection across South Asia, Latin America, and particularly the Middle East and North Africa. Tunisia represents a sustained site of reception within this transnational media flow, where Tu...

Comparison of the Effects of High‐Flow Nasal Cannula Oxygen and Jet Ventilation Techniques

ABSTRACT Objectives Shared airway management in endolaryngeal surgery conflicts surgical access with adequate ventilation. This study compared the effects of High‐Frequency Jet Ventilation (HFJV) and Transnasal Humidified Rapid‐Insufflation Ventilatory Exchange (THRIVE) via High‐...

Topical capsaicin versus diclofenac for chronic temporomandibular joint-related pain: a randomized, prospective, single-blind clinical trial

Chronic temporomandibular joint (TMJ)–related pain is a common condition associated with pain sensitization and functional limitation. Although topical capsaicin and diclofenac diethylammonium are used for musculoskeletal pain, direct comparative evidence in temporomandibular dis...

Volumetric Changes in the Basal Ganglia Over Three Years After Subthalamic Nucleus Deep Brain Stimulation

Supplementary material for the manuscript “Volumetric Changes in the Basal Ganglia Over Three Years After Subthalamic Nucleus Deep Brain Stimulation.” The supplementary material includes Supplementary Figures S1–S2 and Supplementary Tables S1–S4.

Biocompatibility of five occlusal splint materials produced by four fabrication methods: an in vitro comparative study

Abstract Background To evaluate the cytotoxicity, cell death, interleukin-6 (IL-6) release, and surface roughness of five occlusal splint materials produced by four different fabrication methods on L929 mouse fibroblasts. Methods 240 disc-shaped specimens (15 × 2 mm) were fabrica...

Uncertainty-driven connectedness in global gold-mining equities: A Time–Frequency and quantile approach

This study examines how connectedness among global gold-mining equities varies across market regimes, investment horizons, and return states, and whether gold-specific uncertainty adds information beyond gold prices and broad market volatility. The sample comprises eleven gold-mi...

Effect of Glass Fiber and Mineral Filler Reinforcement on the Dielectric Relaxation and Structural Dynamics of PA6 Hybrid Composites

ABSTRACT PA6 (Polyamide 6) hybrid composites (20% glass fiber (GF) and 20% mineral filler mixture of talc and CaCO 3 ) are studied using dielectric spectroscopy (DS) to determine dielectric and structural properties, and to highlight the effect of the reinforcement, filler materi...

Integrated genome-wide DNA methylation and transcriptomic analysis prioritizes EPHA5 as a candidate non-invasive epigenetic biomarker for oral squamous cell carcinoma

Purpose Oral squamous cell carcinoma (OSCC) remains a major clinical challenge because of delayed diagnosis and the lack of validated non-invasive biomarkers for OSCC detection. Epigenetic alterations during oral carcinogenesis represent promising biomarker candidates. This study...

Prediction of Ultra-High-Performance Concrete (UHPC) Compressive Strength in Structural Applications Using Machine Learning: A Comprehensive Evaluation via Multiple Random Seeds and Hyperparameter Optimization

Ultra-high-performance concrete (UHPC) is increasingly being used in academic and commercial applications due to its superior mechanical properties, high durability, and long service life. To ensure that UHPC can be reliably used in structural applications, it is important to pre...

Association of Gastric Microbiota with Gastric Cancer in Patients Infected with Helicobacter pylori

Background: The association between Helicobacter pylori and the resident gastric microbiota plays a critical role in gastric carcinogenesis; however, the specific microbial alterations accompanying the transition from chronic inflammation to malignancy remain to be fully elucidat...

Quality Evaluation of Commercial Products Marketed as Thymus vulgaris L. Essential Oil According to European Pharmacopoeia 10.0 Criteria

Essential oils are mixtures of complex secondary metabolites with variable chemical compositions that determine their therapeutic effects. Thyme oil, obtained from the fresh or dried leaves and flowers of Thymus spp. through steam distillation, is widely used in food, pharmacy, a...

Synthesis, Biological Evaluation, Molecular Docking and DFT Studies of Electronically Tuned Benzylidene-Based Schiff Bases

Inspired by the medicinally relevant stilbene scaffold, a series of six electronically tuned benzylidene-based Schiff base derivatives were designed, synthesized, and characterized by FT-IR, 1H NMR, 13C NMR, and ESI-MS analyses. The biological properties of the synthesized compou...

“It’s not just the pain” understanding fear of childbirth through the lens of body and mind

This study investigated the relationship between haptotherapeutic well-being and fear of childbirth and examined the influence of sociodemographic factors on these variables. A cross-sectional analytical study was conducted with 567 pregnant women receiving antenatal care in east...

Biodiversity of soft-bottom macrozoobenthos along the Sinop coasts (southern Black Sea): influence of environmental drivers

Context The Black Sea faces continuous anthropogenic pressures, requiring updated baseline data to assess coastal benthic habitat resilience. Aims This study evaluates the seasonal taxonomic composition, diversity and community structure of soft-bottom macrozoobenthos along the S...

Machine learning-assisted design of a novel crocin-loaded poloxamer 407/hyaluronic acid in situ forming hydrogel for endometriosis treatment: in vitro characterization and in vivo efficacy evaluation

Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the effects of poloxamer 407 (P407) and hyaluronic acid (HA) concen...

Fresh-semen proAKAP4 concentration predicts sperm cryotolerance independently of conventional semen quality across three goat breeds

Abstract Cryopreservation compromises sperm quality, yet conventional semen analysis poorly predicts which ejaculates will withstand freezing. proAKAP4, a sperm-specific structural protein, is a candidate freezability biomarker, but is usually measured after thawing. We tested wh...