Istanbul University

THE UNIFIED FLUIDIC UNIVERSE (UFU) MODEL: A MECHANICAL PARADIGM FOR VECTORIAL FLOW COSMOLOGY

Contemporary physics relies heavily on field-theoretic approaches and the addition of adhocentities such as dark matter to explain macro-scale phenomena. This manuscriptintroduces the Unified Fluidic Universe (UFU) model, redefining cosmology through thelens of fluid mechanics. W...

Recent Advances and Open Challenges in Mitigating Inference-Time Attacks on Large Language Models

The rapid integration of Large Language Models into high-stakes domains has elevated inference-time attacks into a primary security concern for production deployments. These attacks are adversarial techniques that exploit models exclusively through their input–output interface. T...

Study Clinical Characteristics and Outcomes of Candida auris Candidemia in Adult Intensive Care Unit Patients: A 30-Month Retrospective Study

Background: Candida auris (C. auris) has emerged as a multidrug-resistant fungal pathogen causing healthcare-associated outbreaks worldwide, particularly in intensive care units (ICUs). Its environmental persistence, multidrug resistance, and high mortality make it a major challe...

Reinforcement Learning in Eating Disorders: Clinical, Cognitive, and Metabolic Correlates

OBJECTIVE: Reinforcement learning has been implicated in eating disorders, but findings remain inconsistent. This study compared reinforcement learning performance in anorexia nervosa (AN), bulimia nervosa (BN), and healthy controls (HC) using the Probabilistic Reward Task (PRT),...

Quantum chemical, spectroscopic, and in silico molecular docking and molecular dynamics studies on thymotrinan, which has immunomodulatory and neuroprotective properties

Thymotrinan is an immunomodulating tripeptide containing the Arg-Lys-Asp sequence.In this study, the structural, vibrational, and electronic properties, as well as the bioactivity of thymotrinan, have been thoroughly examined.The conformational preferences of thymotrinan were eva...

A Game-Based Eye-Tracking Task for Inclusive Educational Assessment in Children with Autism Spectrum Disorder and Dyslexia: An Exploratory Study

Background: Inclusive educational assessment requires tools that capture how learners with diverse cognitive profiles engage with tasks. This study examines whether a game-based, gaze-contingent eye-tracking task can generate relevant indicators for inclusive assessment of autist...

Diamond Cut Veneers: The Faceted Monolithic Ceramic Dental Prosthesis — Concept Origin and Priority Record

PURPOSE: This study evaluated the validity of the color selection results obtained from digital cameras. MATERIALS AND METHODS: Four observers matched the colors of 30 extracted maxillary incisors under daylight conditions. Two different digital cameras, with 1.5- and 5.0-megapix...

Machine learning-based winner prediction in elite kickboxing: a technical-tactical performance analysis

To develop and validate machine learning models for predicting match outcomes in elite kickboxing based on technical-tactical performance indicators and to identify the key variables distinguishing winners from defeated athletes. Video analysis was conducted on 142 elite kickboxi...

ACUTE NECROTISING PANCREATITIS CAUSED BY SODIUM VALPROATE: A CASE REPORT

Valproic acid (sodium valproate; VPA)-associated pancreatitis is an uncommon but potentially life-threatening adverse event, particularly in children. Although pancreatitis related to valproate therapy is reported more frequently in pediatric patients than in adults, necrotizing...

Factors associated with mortality in Staphylococcus aureus bacteremia: the role of infectious diseases consultation

This study aimed to determine the predictors of 14th and 28th day mortality in Staphylococcus aureus bacteremia and to evaluate the risk factors of methicillin-resistant S. aureus (MRSA). Our study, designed as a single-center retrospective observational study, included adult pat...

A cluster-aware XAI-MCDM framework for province-level solar PV suitability screening in Turkey using real operational PV data

Abstract Identifying suitable regions for solar photovoltaic (PV) deployment is commonly addressed through GIS- and multi-criteria decision-making (MCDM)-based frameworks; however, criterion weights in such studies are often derived from expert judgement or purely statistical ass...

GROUND-STATE NEGATIVITY OF TRUNCATED CONNES-VAN SUIJLEKOM FORMS FOR DIRICHLET L-FUNCTIONS.

The Connes-van Suijlekom (CvS) framework associates to a real distribution Don [0, L] a finite Galerkin matrix whose ground state encodes spectral data of an associated L-function. We construct the CvS kernel for real primitive Dirichlet characters $\chi_{D}$ D a fundamental disc...

From "Made in China" to "Made in Türkiye" in International Trade: a Systematic Literature Review of Manufacturing Power, Technological Upgrading, and Nation Branding

The transformation of global competition from a predominantly cost-based structure towards technological capability, innovation, sustainability, and brand value has expanded the meaning of “made in” labels beyond the mere identification of a product’s country of manufacture. Thes...

The impact of Socratic method on middle school students achievement in non-routine problem solving and their attitudes toward mathematical problem solving

Non-routine problems play a significant role in mathematics learning due to their potential to foster students’ reasoning, inquiry, and critical thinking skills. Students, however, often experience difficulties in solving these problems and may experience negative attitudes towar...

From "Made in China" to "Made in Türkiye" in International Trade: a Systematic Literature Review of Manufacturing Power, Technological Upgrading, and Nation Branding

The transformation of global competition from a predominantly cost-based structure towards technological capability, innovation, sustainability, and brand value has expanded the meaning of “made in” labels beyond the mere identification of a product’s country of manufacture. Thes...

Trifluoromethyl-Benzimidazole-Hydrazone Derivatives as Promising Selective Anticancer Agents: Synthesis, Cytotoxicity, and Molecular Docking Insights

Background/Objectives: Benzimidazole and hydrazone scaffolds are widely investigated in anticancer drug discovery because of their structural versatility and capacity to interact with multiple cancer-related targets. This study aimed to synthesize a series of trifluoromethyl-subs...

Bridging Parental Perceptions and Experiences of Family‐Centered Care in the Pediatric Intensive Care Unit: A Mixed‐Methods Study

AIM: To examine parents' perceptions and experiences of family-centered care in a pediatric intensive care unit and explore how communication, participation in care, and contextual factors shape these experiences. DESIGN: An explanatory sequential mixed-methods design was used. M...

Technology adoption drives entrepreneurial performance through integrated PEST factors supporting sustainable economic growth and innovation

Entrepreneurial performance in emerging economies is shaped not only by macro-environmental conditions but also by entrepreneurs’ ability to adopt and leverage digital technologies. However, empirical research remains limited in explaining how political, economic, social, and tec...

Assessing the Educational Role of Large Language Models in Dental Training: A Decade‐Long Analysis of Text‐Based and Visual Questions in a National Examination

ABSTRACT Background Large language models (LLMs), including ChatGPT, Gemini and DeepSeek, are increasingly explored as supportive tools in health professions education. However, their educational utility across different knowledge domains and question formats, particularly those...

Precision oncology in the treatment of patients with bone sarcomas: an up-to-date narrative review

Primary bone sarcomas are rare and biologically heterogeneous malignancies for which therapeutic progress remains limited, particularly in metastatic and recurrent disease. Advances in genomic and molecular profiling have revealed substantial inter- and intratumoral heterogeneity...