Ghent University

From gatekeepers to regenerators: the plasticity of Paneth cells

Paneth cells (PCs) are secretory cells in the small intestine with functions in intestinal homeostasis and innate immunity, with recent studies showing their ability to dedifferentiate and contribute to epithelial regeneration after injury. In this issue of The EMBO Journal, Yang...

StereoBed - salvage stereotactic body radiotherapy of the prostate bed for biochemical recurrence after radical prostatectomy: study protocol for a randomized phase II/III trial

In cases of biochemical recurrence (BCR) after radical prostatectomy, salvage radiotherapy (RT) is a well-established standard-of-care treatment. Stereotactic body radiotherapy (SBRT) may offer a shorter treatment duration and favorable radiobiological characteristics, but eviden...

Vitrification and encapsulation modules for back-end simulation in ANICCA

In nuclear fuel cycle simulations, the back-end is often represented through cumulative spent fuel or high-level waste (HLW) inventories, while conditioning and packaging steps are simplified or omitted. This is especially limiting for advanced recycling strategies, including min...

Mechanical behavior and fracture mechanisms of rock-backfill composites under different hole geometries and backfill conditions

Abstract Rock-backfill composites, as key load-bearing structures in deep mining, exhibit mechanical behavior and failure mechanisms that are predominantly controlled by excavation-induced hole geometry and backfill conditions. In this work, a series of uniaxial compression tests...

Inference of Microporosity Phase Properties in Heterogeneous Carbonate Rock With Data Assimilation Techniques

Abstract Accurate digital rock modeling of carbonate rocks is limited by the difficulty in acquiring morphological information on small‐scale pore structures (microporosity phases in computed tomography images), which provide crucial connectivity and contribute significant surfac...

From Waste to Wealth: Boosting Productivity in Kenyan Smallholder Farmer Fields with Fluopyram-Treated Banana Fibre

Potato (Solanum tuberosum) is a key staple crop in Kenya, where plant-parasitic nematodes are among the most damaging yield constraints for smallholder farmers. This study evaluated fluopyram-treated banana fibre paper, a biodegradable carrier for targeted delivery of ultra-low n...

Standardised and collaborative approaches to the development of tools to control infectious and zoonotic diseases in livestock using STAR IDAZ IRC roadmaps

Abstract The Strategic Alliance for Research into Infectious Diseases of Animals and Zoonoses (STAR IDAZ) International Research Consortium (IRC) is a global network of funders and scientists with interests in livestock health and wellbeing. STAR IDAZ IRC provides a unique platfo...

The PROTECT-study (PROsthesis TElerehab Care Trial), home-based telerehabilitation in post-operative care after shoulder arthroplasty compared to usual care: study protocol for a randomized clinical trial

Total shoulder arthroplasty (TSA) has become a commonly used procedure for patients with degenerative shoulder complaints such as severe osteoarthritis, cuff tear arthropathy and for revision surgery. After surgery, patients are generally referred to a physical therapist for reha...

Electrostatic Reconfiguration of Photo‐Patterned Periodic Structures With Half‐Integer Twist Disclination Lines in Ferroelectric Nematic Liquid Crystals

ABSTRACT The recently discovered ferroelectric nematic liquid crystals, combining fluidity with spontaneous polarization, offer unique opportunities for engineering polar domain structures for (nonlinear) photonic applications. A central challenge lies in achieving precise contro...

Evaluation of a Novel Isothermal Microcalorimetry-Based Sterility Test

Abstract Parenteral drugs must meet strict release criteria to ensure patient safety upon administration. Sterility is a critical requirement, and is typically assessed using the compendial U.S. Pharmacopoeia (USP) <71> sterility test. However, with the growing demand to reduce b...

Contrasting patterns of trematode and host snail dispersal across clusters of tropical crater lakes

Abstract Background Comparing the genetic diversity and population structure of parasites and their hosts can improve understanding of their respective methods of dispersal, demographic histories, and factors driving genetic differentiation. In parasite taxa such as trematodes wh...

Dose-dependent microbiome, metabolome and lipidome shifts in a mouse model of colitis-associated colorectal cancer using azoxymethane and dextran sodium sulphate

Colorectal cancer (CRC) remains a major health burden, underscoring the need for continued research to improve screening methods and treatment outcomes. The colitis-associated azoxymethane (AOM) and dextran sodium sulphate (DSS) mouse model has proven valuable for CRC research, a...

Cellular automata can really solve the parity problem

Abstract Determining properties of an arbitrary binary sequence is a challenging task if only local processing is allowed. Among these properties, the determination of the parity of 1s by distributed consensus has been a recurring endeavour in the context of automata networks. In...

Melanins Enhance Radical Scavenging Through Wavelength‐Selective Excited‐State Manifold Diversity

ABSTRACT Melanin is a ubiquitous pigment that mitigates photoinduced damage in biological systems through light absorption, heat dissipation, and radical scavenging. While these functions have traditionally been considered independent, recent studies suggest that they may be intr...

When networking pays unequally: proactive personality, gender and career satisfaction in Vietnam and the United States

Purpose This study investigates how proactive personality shapes employees’ career networking and career satisfaction across two national contexts and whether the career returns to networking differ by gender. Drawing on the social role theory, we argue that proactive employees a...

P1.005. Preliminary Pilot Study Cohort Results - Cost-Effective Surveillance Strategies and Prediction of Cancer Recurrence After Endoscopic Therapy for Barrett’s Esophagus (Endeavor)

Abstract Topic Esophageal Cancer: Barrett‘s Esophagus: High-Grade Dysplasia and Early Invasive Cancer Background In many European countries, esophageal adenocarcinoma (EAC) incidence is increasing [1]. Barrett’s esophagus(BE), strongly associated with EAC, can progress via dyspla...

Between-session chasing via time of return in online eCasino gambling

Abstract Background and aims Chasing refers to continuing and/or intensifying gambling following losses (loss-chasing) and/or wins (win-chasing). It is commonly captured between sessions, i.e., returning another day/time after losses or wins in prior sessions. Between-session cha...

Co-creating an intergenerational intervention to enhance physical activity in the older adult population: A qualitative study of the engAGE project

Background Older adults are the most sedentary population segment, and effective, sustainable interventions are needed to modify these behaviours. Intergenerational and participatory approaches may enhance adherence and support long-term engagement. This study reports on the co-c...

Service user and healthcare-worker perspectives on Substance Use Disorder treatment journeys, relapse, and recovery in Sub-Saharan Africa: Evidence from Uganda

Abstract Introduction Substance Use Disorders (SUDs) pose significant public health challenges in sub-Saharan Africa. However, there is limited evidence on how service users (SUs) and front-line health care workers (HCWs) experience SUD treatment and recovery within resource cons...

Evaluation of the Pulp Space Morphology of the Mandibular Premolars in a Greek Population by Cone Beam Computed Tomography

Background/Objectives: This study aims to evaluate the pulp space morphology (PSM) of both first and second mandibular premolars in a sample of a Greek population using cone beam computed tomography (CBCT). Methods: Two hundred and ninety nine CBCTs of a Greek population were ass...