Ghent University

Environmentally induced dynamics between intraindividual variation and trait means across vegetative, phenological, and floral traits

PREMISE: Intraindividual variation in reiterated structures (e.g., leaves) represents an important dimension of phenotypic variation that contributes to functional diversity and the dynamics of ecological communities. It can be expressed differently across plant traits, but how e...

Integrative benchmarking and automation of clonal reconstruction of somatic mutations in single-sample tumor genome analysis

Abstract Background Accurate identification of truncal mutations, those present in all tumor cells, is essential for understanding tumor evolution and guiding downstream analyses in cancer genomics, including detection of minimal residual disease. Existing clonal reconstruction t...

MechanochemicalSynthesis of [Rh(L)(acac)(CO] Complexes(L = N-Heterocyclic Carbene or Phosphine)

Abstract The mechanochemical synthesis of well-defined [Rh(L)(acac)(CO)] (L = NHC or phosphine) complexes via planetary milling and manual grinding with a mortar and pestle is reported. This solventless protocol, which proceeds via a ligand displacement from [Rh(acac)(CO)2], was...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...

Reduced Food Availability Amplifies Behavioral Depression and Impairs Locomotor Performance After Immune Challenge in Xenopus laevis

Mounting an immune response and locomotor activity are energetically costly processes that can generate trade-offs affecting energy allocation, muscle performance, and activity patterns. The balance between these demands can be modulated by factors such as food availability and e...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

Bone Accrual During Puberty Suppression and Gender-Affirming Therapy in Transgender Adolescents

Importance Puberty is a critical window for bone mass acquisition, determining lifelong fracture risk. Gonadotropin-releasing hormone agonist (GnRHa)–based pubertal suppression followed by gender-affirming hormone therapy (GAHT) is increasingly used in transgender and gender-dive...

Derivation of a Bioavailability-Based Environmental Quality Standard for Copper in European Freshwaters under the Water Framework Directive using an updated methodology

Copper (Cu) is a river basin specific pollutant under the European Water Framework Directive (WFD). Compliance assessment under the WFD should be based on a tiered approach that considers a bioavailability correction integrating local physico-chemistry conditions. The existing pr...

The perceptions and practices of speech-language pathologists in Turkiye regarding therapy approaches for children who stutter focusing on the Lidcombe Program

PURPOSE: The Lidcombe Program is an evidence-based treatment for early stuttering. Although negative attitudes towards direct stuttering therapies have previously been reported among Turkish speech-language pathologists, these data are outdated, and this study updates the field b...

Longitudinal characterization of medial gastrocnemius muscle growth deficits throughout childhood in spastic cerebral palsy

The prospective longitudinal study compared muscle growth in children with spastic cerebral palsy (CP) with typically developing (TD) peers and across Gross Motor Function Classification System (GMFCS)-groups, and investigated muscle deficit trajectories across GMFCS-groups. Thre...

Strategic Fit Matters: How Family Entrepreneurial Configurations Shape Performance in Coffee and Banana Family Farms in Uganda

Abstract Smallholder family farms are often depicted as constrained, subsistence-oriented, or pressured to “grow or go.” However, some small family farms outperform others despite operating under similar resource constraints. Using configuration theory, this study examines how fa...

Parents in the making: A critical encounter between bioethical theory and “Homegrown” accounts of moral parenthood

In this paper, we explore questions of moral parenthood by setting up a critical encounter between accounts developed by bioethicists and the perspectives of prospective PACT (Pre-conception Agreement-Based Co-parenting Together-apart) parents. This particular approach attends to...

Discontools supplement Mycoplasma hyopneumoniae infections in pigs: update and knowledge gaps

This manuscript reviews current knowledge on Mycoplasma hyopneumoniae , the primary agent of enzootic pneumonia in pigs, integrating advances in epidemiology, pathogenesis, immunity, diagnostics, and control. The pathogen is globally endemic, with transmission driven mainly by di...

Transport disadvantage and suppressed travel among low-income older adults: Lived experiences of social housing tenants in Ghent

Transport disadvantage is widely researched, yet less is known about how mobility constraints translate into suppressed travel: desired but unrealised trips. This paper examines suppressed travel among low-income older adults, focusing on social housing tenants in Ghent, Belgium....