Ghent University

Dose-dependent microbiome, metabolome and lipidome shifts in a mouse model of colitis-associated colorectal cancer using azoxymethane and dextran sodium sulphate

Colorectal cancer (CRC) remains a major health burden, underscoring the need for continued research to improve screening methods and treatment outcomes. The colitis-associated azoxymethane (AOM) and dextran sodium sulphate (DSS) mouse model has proven valuable for CRC research, a...

When networking pays unequally: proactive personality, gender and career satisfaction in Vietnam and the United States

Purpose This study investigates how proactive personality shapes employees’ career networking and career satisfaction across two national contexts and whether the career returns to networking differ by gender. Drawing on the social role theory, we argue that proactive employees a...

Melanins Enhance Radical Scavenging Through Wavelength‐Selective Excited‐State Manifold Diversity

ABSTRACT Melanin is a ubiquitous pigment that mitigates photoinduced damage in biological systems through light absorption, heat dissipation, and radical scavenging. While these functions have traditionally been considered independent, recent studies suggest that they may be intr...

Cellular automata can really solve the parity problem

Abstract Determining properties of an arbitrary binary sequence is a challenging task if only local processing is allowed. Among these properties, the determination of the parity of 1s by distributed consensus has been a recurring endeavour in the context of automata networks. In...

P1.005. Preliminary Pilot Study Cohort Results - Cost-Effective Surveillance Strategies and Prediction of Cancer Recurrence After Endoscopic Therapy for Barrett’s Esophagus (Endeavor)

Abstract Topic Esophageal Cancer: Barrett‘s Esophagus: High-Grade Dysplasia and Early Invasive Cancer Background In many European countries, esophageal adenocarcinoma (EAC) incidence is increasing [1]. Barrett’s esophagus(BE), strongly associated with EAC, can progress via dyspla...

Service user and healthcare-worker perspectives on Substance Use Disorder treatment journeys, relapse, and recovery in Sub-Saharan Africa: Evidence from Uganda

Abstract Introduction Substance Use Disorders (SUDs) pose significant public health challenges in sub-Saharan Africa. However, there is limited evidence on how service users (SUs) and front-line health care workers (HCWs) experience SUD treatment and recovery within resource cons...

Co-creating an intergenerational intervention to enhance physical activity in the older adult population: A qualitative study of the engAGE project

Background Older adults are the most sedentary population segment, and effective, sustainable interventions are needed to modify these behaviours. Intergenerational and participatory approaches may enhance adherence and support long-term engagement. This study reports on the co-c...

Between-session chasing via time of return in online eCasino gambling

Abstract Background and aims Chasing refers to continuing and/or intensifying gambling following losses (loss-chasing) and/or wins (win-chasing). It is commonly captured between sessions, i.e., returning another day/time after losses or wins in prior sessions. Between-session cha...

Evaluation of the Pulp Space Morphology of the Mandibular Premolars in a Greek Population by Cone Beam Computed Tomography

Background/Objectives: This study aims to evaluate the pulp space morphology (PSM) of both first and second mandibular premolars in a sample of a Greek population using cone beam computed tomography (CBCT). Methods: Two hundred and ninety nine CBCTs of a Greek population were ass...

In Vitro Pharmacological Characterization of a Series of 5‐Cyano Desnitazene Opioids or “Cyanazenes”

ABSTRACT The new synthetic opioid (NSO) market has been reshaped by the emergence of an opioid class known as “nitazenes,” 2‐benzylbenzimidazole opioids spanning a wide potency range, with several analogues surpassing the potency of fentanyl. The recently identified compound 5‐cy...

A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis

Abstract Reactive oxygen species (ROS) are central regulators of plant growth and stress responses. Cellular ROS levels are tightly controlled by antioxidant systems, including the evolutionarily conserved catalases that detoxify hydrogen peroxide (H 2 O 2 ) predominantly within...

European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines for antimicrobial and non-steroidal anti-inflammatory drug use in bovine respiratory disease

<ns5:p> Background Bovine respiratory disease (BRD) is a major cause of morbidity, mortality, impaired welfare, production loss, and antimicrobial use in cattle. These European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines provide evidence-based...

Improving Functional Oral Intake in Head and Neck Cancer Survivors with Chronic Radiation-Associated Dysphagia – The Multicenter Randomized Controlled HIT-CRAD Trial

This randomized controlled trial evaluated the efficacy of home-based treatment programs for chronic radiation associated dysphagia (CRAD) in head and neck cancer (HNC) patients, comparing high-volume strength training to combined strength-skill training with either real or sham...

Widespread thermophilization but weak link to climate warming in Europe’s summit plant communities

Abstract Recent changes in alpine vegetation are often attributed to climate warming, particularly community composition shifts towards more warmth-associated species, or thermophilization. Here we assess the link between thermophilization and warming across 53 European mountain...

Availability and representativeness of freshwater macroinvertebrate data to enable Europe-wide assessment of biodiversity trends

Freshwater ecosystems, though covering less than 1% of Earth's surface, harbor around 10% of all species. Pressures like pollution, water extraction, and habitat loss can exhibit complex interactions in their effects on freshwater biodiversity. Understanding the effects of these...

Integrated single-cell transcriptomic, proteomic, and tissue-level analysis defines cancer-associated fibroblast programs in pseudomyxoma peritonei

Pseudomyxoma peritonei (PMP) is an ultra-rare mucinous neoplasm with extensive stromal remodeling, yet the role of cancer-associated fibroblasts (CAFs) remains poorly defined. A PMP-derived CAF culture was established and characterized through multiple omics and phenotypic assays...

Groundwater Aquifer Characterization and Potential Assessment of the Shallow Aquifers in the Volcanic Highlands of Northwestern Ethiopia

Estimating transmissivity and hydraulic conductivity is crucial for groundwater resource assessment, flow modeling, pollution remediation, and sustainability studies. In the volcanic highlands of Ethiopia, millions rely on hand-dug wells and springs for drinking and irrigation, y...

A cooperative regulatory module between TAGL2 and JMJC1 activates specific defense genes against root‐knot nematodes in tomato

Summary Plant‐parasitic nematodes (PPNs) threaten global food security. Although epigenetic modifications are crucial for plant immunity, how histone modifiers contribute to root‐knot nematodes (RKNs, Meloidogyne incognita ) resistance remains unclear. Here, using genetic, molecu...

Effects of different volumes of a water-soluble and biodegradable nesting material on behavior, pain, glycemia, farrowing traits, and performance in crated sows

Abstract This study evaluated the effects of providing 3–15 kg of a soluble and biodegradable biopolymer-based enrichment material (blend of biodegradable polymers and natural fibers) to prepartum sows housed in farrowing crates. Fifteen sows were blocked by body weight and backf...

Larval ExposureRather than Adult Worm Burden ShapesSystemic and Mucosal Th2 Immunity in Ascaris suum Infected Pigs

Abstract Ascariasis is a prevalent parasitic infection in both humans and pigs, resulting in significant human morbidity and economic losses in the porcine industry. Experimental infections are often studied by mimicking natural settings, exposing the host to frequent, small dose...