Emory University

Care Models for the Genetic Evaluation of Dilated Cardiomyopathy at Sites of the DCM Consortium

Abstract Background Clinical genetic evaluation for patients with dilated cardiomyopathy (DCM) is minimally implemented and models of care are not defined. To understand current genetics care for DCM, a systematic needs assessment was conducted. Methods Principal Investigators (P...

Post‐traumatic Psychopathology and Cardiovascular Risk: A Danish Case–Control Study of Sex‐Specific Associations

Background There is increasing recognition that trauma exposure and related psychiatric consequences predict cardiovascular disease risk. However, most research has specifically examined post‐traumatic stress disorder—despite evidence that a range of psychiatric disorders may fol...

Functionally active lymphoid aggregates correlate with improved prognosis in brain metastases

Abstract B cells and their cellular neighborhoods, i.e., lymphoid aggregates (LAs) and tertiary lymphoid structures (TLS), have not been extensively studied in melanoma brain metastases (BM) or lung adenocarcinoma (LUAD) BM, despite their prognostic value and role in immunotherap...

Secondary use and scholarly impact of a portfolio of clinical trials with shared individual participant level data: cross sectional study

Abstract Objective To assess the number, timing, characteristics, and scholarly impact of secondary publications generated using individual participant level data (IPD) from a portfolio of clinical trials shared with external investigators through a data sharing platform. Design...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...

Workplace Discrimination Affecting Nurse Practitioners in US Hospitals

Background Workplace discrimination remains a concern in health care, contributing to burnout and turnover among nurses, particularly those belonging to racial and ethnic minority groups. Although evidence is growing for staff nurses, little is known about discrimination among ho...

Statewide E-Cigarette Flavor Ban Policies and E-Cigarette Use Among US Adults, 2018-2023.

. 2026;116(9): 1416-1425. https://doi.org/10.2105/AJPH.2026.308645).

Risk of Recurrence in Patients with HR+/HER2− Early Breast Cancer: A Podcast

Within 20 years of diagnosis, up to 27% of patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative early breast cancer will experience recurrence, despite standard-of-care treatments. Of these recurrences, approximately half will occur within 5 y...

The geography of immigrants in same-sex couples in the United States

The policy landscape for same-sex couples in the United States has changed rapidly in recent years, and the number of immigrants in same-sex couples has markedly increased. Little is known, however, about where these lesbian, gay, bisexual, and queer (LGBQ) immigrants settle and...

Mixed-Methods Process Evaluation of the Pilot Implementation of an Inclusive Teaching Reflection Tool for Public Health Education

Initiatives by schools and programs of public health are crucial to support instructors in further integrating inclusive pedagogies into their teaching. We conducted a process evaluation of the pilot implementation of an Inclusive Teaching Reflection Tool at Emory University’s Ro...

PrEP reinitiation, uptake, and persistence as targets for reducing HIV incidence and racial and ethnic inequities among men who have sex with men in Boston, USA: a network modeling study

Background A decade of pre-exposure prophylaxis (PrEP) has lowered HIV incidence among men who have sex with men (MSM) but not enough to meet Ending the HIV Epidemic goals, and racial and ethnic disparities persist. The PrEP era has produced a population of former users facing lo...

18F-fluciclovine PET Imaging of Non-PSMA Expressing High-risk Primary Prostate Cancer

A 67-year-old man with rising PSA and palpable prostate lesion underwent prostate MRI, which showed a large PI-RADS 5 lesion confirmed on biopsy as Gleason score 9 (4+5), grade group 5, prostate cancer. 18 F-DCFPyL PET/CT scan for initial stage showed no significant PSMA avidity...

Association of prenatal exposure to opioids, cannabis, and polysubstance use with cord blood DNA methylation patterns in a multiancestry cohort

Abstract Background: Blood DNA methylation patterns are highly predictive of prenatal exposure to smoking and differential methylation has been associated with maternal alcohol use. We extended this to determine whether DNA methylation patterns in cord blood are associated with p...

Immunological imprinting shapes the cross-reactive antibody responses to the KP.2 and LP.8.1 vaccine doses

The emergence of the SARS-CoV-2 Omicron BA.2.86 subvariant, a lineage derived from the BA.2 strain, led to the 2024-2025 COVID-19 vaccine update to include KP.2 or related JN.1-lineage spike antigens. We evaluated the magnitude, breadth, and durability of humoral immune responses...

Pediatric Hospital Medicine Board-Certified and Non–Board-Certified Hospitalists Are Welcome Here

The Consortium of Pediatric Hospital Medicine, representing elected leaders in the field of Pediatric Hospital Medicine (PHM), proudly welcomes and fully supports every pediatric hospitalist, sub-board certified and non–sub-board certified alike, as integral contributors to our c...

Form and function of actin impacts actin health and aging

Abstract The actin cytoskeleton is a fundamental and highly conserved structure that functions in diverse cellular processes, yet its direct contribution to organismal aging remains unclear. Here, we systematically interrogated how genetic and pharmacologic perturbations of actin...

Multifocal Epithelioid Hemangioma With FOSB Overexpression

ABSTRACT Epithelioid hemangioma (EH) is a benign vascular tumor that most commonly arises on the skin but may also occur in other anatomical locations, including deep soft tissue, bone, visceral organs, penis, and mucosal sites. A hallmark of EH is overexpression of FOS and FOSB...

Fabry Disease: An Updated Perspective and Review of Treatment and Therapies

Fabry disease (FD) is a progressive, multisystemic, X-linked lysosomal storage disorder that when untreated leads to decreased quality of life, chronic pain, and end organ disease; however, advances in therapy have significantly altered its original natural history. This paper br...

Predictive functional network connectivity signature of infancy age and eye-region fixation behavior

Functional connectivity (FC) has been established as a fundamental property of brain organization, intricately linked to both neurodevelopmental processes and the emergence of social behavior. Prior research has demonstrated that individual variability in brain age is associated...

The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023

Background The cardiovascular-kidney-liver-metabolic (CKLM) framework represents the multi-organ interplay of systemic metabolic disorders that drive the global burden of cardiovascular diseases (CVD). Methods This study is a descriptive epidemiological analysis of the Global Bur...