Baylor College of Medicine

Injury Severity and Near-Absent Helmet Use in NTDB-Eligible Pediatric E-Scooter Trauma: A Single-Center Descriptive Series

Pediatric e-scooter injuries have risen rapidly, yet single-center data describing injury severity, admission patterns, and helmet use within high-acuity trauma populations remain limited. We describe a single-center retrospective series of 31 National Trauma Data Bank (NTDB)–eli...

The Impact of Earthquake-Induced Healthcare Disruption on an Established Developmental Hip Dysplasia Screening Program in an Earthquake Zone

Background/Objectives: Pandemics and natural disasters may delay the diagnosis and treatment of developmental dysplasia of the hip (DDH). In this study, we evaluated the effect of 2023 Kahramanmaraş earthquake-induced healthcare disruption on the DDH screening program. Methods: M...

The Triple Win: The Influence of Institution-Sponsored Volunteering on Faculty and Staff Wellbeing and Satisfaction

Abstract Employer-supported volunteering, including volunteer time-off (VTO), has been associated with positive work-related outcomes and may mitigate burnout. This report describes a five-year VTO initiative for faculty and staff at Baylor College of Medicine’s School of Health...

Pregnancy Ambivalence, History of Pregnancy, Condom Use, and Contraceptive Use Among U.S. Youth Experiencing Homelessness

Youth experiencing homelessness (YEH) are 5–8 times more likely than housed peers to become pregnant. A more nuanced examination of YEH pregnancy desire may better inform pregnancy and pregnancy prevention guidance. This study examined pregnancy ambivalence, pregnancy history, co...

Growth Differentiation Factor-15 in Acute Coronary Syndromes: Prognostic Value and Barriers to Clinical Implementation

High-sensitivity cardiac troponin has made the diagnosis of myocardial infarction (MI) faster and more precise, but it does not measure the broader biological vulnerability that often determines the outcome after an acute coronary syndrome (ACS). Growth differentiation factor-15...

The impact of structural variation on Alzheimer’s disease in the Alzheimer’s disease sequencing project

Structural variants (SV), genomic alterations spanning more than 50 base pairs, can significantly impact gene expression and protein function. However, their contribution to Alzheimer’s disease (AD) remains poorly understood. Leveraging a novel SV calling pipeline, we identified...

HIF1A-dependent induction of alveolar miR-147b dampens SARS-CoV-2-associated ARDS via direct targeting of viral RNA

BACKGROUND: Acute respiratory distress syndrome (ARDS) causes significant morbidity and mortality during viral pneumonia, including SARS-CoV-2 infections. Nevertheless, most patients with SARS-CoV-2 infections recover seamlessly without developing ARDS, suggesting the existence o...

Molecular Machines Enhance Insulin Release in Pancreatic Beta Cells

ABSTRACT The production and secretion of insulin by pancreatic beta cells plays a critical role in glucose homeostasis. Insulin signaling dysfunction typically results in diabetes mellitus, which affects over 415 million people worldwide. The development of new tools to induce in...

Adapting the MasSpec Pen for noninvasive detection of oral cavity squamous cell carcinoma

Oral Cavity Squamous Cell Carcinoma (OCSCC) is a common and deadly form of head and neck cancer which disproportionately afflicts low- and middle-income communities. Since the majority of OCSCC lesions are visible within the oral cavity, visual exam-guided biopsy remains the stan...

Impact of an unrestricted clear liquid fasting protocol on pediatric perioperative outcomes: a prospective interventional study

PURPOSE: Traditional preoperative fasting guidance (6-4-2) aims to reduce aspiration risk but frequently produces prolonged fasting and discomfort in children. We evaluated whether progressively liberalizing the clear-liquid fasting policy reduces fasting time and improves the pe...