Research works

Hydro-Mechanical Degradation and Progressive Failure of Sandstone–CGFB Composite Structures Under Cyclic Water Immersion: Implications for Water-Induced Instability Risk in Backfilled Goafs

Sandstone and cemented coal gangue-fly ash backfill (CGFB) form composite load-bearing structures in goafs, where repeated water ingress and drainage may weaken stability. This study investigated sandstone–CGFB composite specimens subjected to 0, 3, 6, and 10 water immersion–dryi...

ANALYSIS OF THE DESIGN AND OPERATING CHARACTERISTICS OF THE SIGMATIC PS WIDE‑WIDTH IRRIGATION MACHINE WITH A SWIVEL PIVOT SHAFT

Based on the technical description, factory operating manuals, and archival materials of the VHJ Sigma Olomouc concern (now Sigma Group a.s.), the article provides a comprehensive historical and technical analysis of the Sigmatic PS wide‑area circular sprinkler machine with a swi...

Causal associations between chronic hepatitis B and major depressive disorder in East Asian populations: a bidirectional two-sample Mendelian randomization study

BACKGROUND: Epidemiological studies suggest that there is a strong association between chronic hepatitis B (CHB) and major depressive disorder (MDD). However, it remains uncertain whether these associations are causal, as much of the current evidence originates from observational...

Qualification of Targeted Attribute Quantitation and New Peak Detection for Automated Multi-Attribute Method Workflows Using Liquid Handling Systems

Background/Objectives: The Multi-Attribute Method (MAM) uses LC-MS peptide mapping for targeted attribute quantitation (TAQ) and untargeted New Peak Detection (NPD) in product quality monitoring and quality control of biotherapeutics. As automated liquid handling systems are adop...

Hydroxypheophytin a Stereoisomers as Principal Bioactive Compounds from Spirulina for the Reduction of Lipids and Appetite

Abstract The rising prevalence of obesity calls for the development of novel treatments. Spirulina is known for its beneficial effects on metabolic health; however, the specific bioactive compounds have not yet been identified. This work aims to address this gap through the bioas...

Adaptive Plasma‐Membrane Nanodomains in Plants: Integrating Lipids, Receptors, Mechanics and Trafficking During Stress

The plant plasma membrane is a chemically asymmetric, mechanically coupled and actively renewed interface in which lipids, receptors, ion channels, transporters and scaffolds form transient nanoscale assemblies. Direct evidence from a limited number of plant systems shows that me...

Delayed Emergence Due to Prolonged Mivacurium Blockade in a Child with Markedly Reduced Butyrylcholinesterase Activity: A Case Report

Background: Delayed emergence after general anesthesia in pediatric patients is uncommon and requires prompt evaluation of pharmacological, metabolic, and neurological causes. Residual neuromuscular blockade remains an important reversible cause, particularly when short acting ne...

Genome-Wide Characterization of the Common Buckwheat B-Box Gene Family and Identification of FeBBX11 and FeBBX27 Involved in Flavonoid Biosynthesis

Flavonoids, a class of secondary metabolites in higher plants, exert a broad range of health-promoting effects by enhancing antioxidant activity. B-box (BBX) transcription factors are reportedly involved in the regulation of flavonoid biosynthesis. However, the roles and function...

The early-onset pancreatic cancer paradox: a systematic review and meta-analysis

BACKGROUND: Globally, the rate of early-onset pancreatic cancer (EOPC) is increasing, but its clinical features and outcomes relative to average-onset pancreatic cancer (AOPC) remain uncertain. We compared clinicopathological features, treatment patterns, and survival outcomes. M...

Effects of E-Liquids and Their Aerosols with and Without Flavors on OKF6/TERT-2 Oral Epithelial Cells: Consequences of Heating and Aerosolization on Cell Viability

Background: Multiple effects of flavored E-liquids or E-liquid aerosols on various cell lines have been reported. However, concentrations of E-liquids and aerosols are not usually equivalent, making it difficult to determine the relative effect heating and aerosolization plays on...

Impact of surgical antibiotic prophylaxis on postoperative complications following dental extractions in dogs with severe periodontal disease: a retrospective observational study

Abstract Background Periodontal disease is the most prevalent oral disease affecting dogs and cats and often requiring surgical treatment. The use of perioperative surgical antimicrobial (SAP) prophylaxis in dental surgery remains a subject of ongoing debate. Dental extractions a...

Market waste composition, biomethane yield, and energy potential in Nairobi, Kenya

Introduction: Municipal solid waste (MSW) management remains a critical sustainability challenge in rapidly urbanizing cities, particularly in Sub-Saharan Africa where inadequate infrastructure and reliance on unsanitary landfills exacerbate greenhouse gas emissions. Nairobi, Ken...

Prime Randomness Questioned in 2025 Number Theory Video Titles — E8 Intelligence Research

FINDING: The video titles indicate a cluster of number-theory expositions and 2025 breakthroughs, but no single new theorem is extractable from titles alone; the strongest signal is the claim that primes may not be random, and the "discoveries that shouldn't exist" theme. | MATH:...

Self-sustaining microbattery fueled by pectin via enzymatic catalysis

Bio-derived self-sustaining microbatteries are promising power sources for implantable and wearable electronics due to their excellent biocompatibility and biodegradability. However, their practical deployment is hindered by limited operational lifetime and low energy density, pr...

Who is eligible for lung cancer screening, and where are they? National subpopulation estimates of people eligible for lung cancer screening

BACKGROUND: The utilization of lung cancer screening services is less than 20%. There are a myriad of barriers at the patient, provider, and health care system levels that account for such low uptake. One reason lung cancer screening rates remain low is that identifying who is el...

Behind the “Game Changer” Spectacle

Abstract Existing research on the China-Pakistan Economic Corridor (CPEC) has predominantly focused on its macroeconomic and macropolitical aspects, leaving its consequences for microlevel development and the local political economy in Pakistan understudied. Scholars have stresse...

Concilier valeurs, collaboration et supply chain : le cas d’une entreprise engagée

Cette étude de cas analyse la manière dont Founty, une PME à mission créée en 2023, met en œuvre la collaboration au sein de sa supply chain en mobilisant des valeurs de durabilité, d’inclusion sociale et d’empowerment. La méthodologie repose sur une étude de cas qualitative fond...

E8 Phase-Locked Prime Gap Modulation via Non-Commutative Spectral Drift — E8 Intelligence Research

Building on the 30-node Fibonacci spectral convergence, we discover that prime gaps are governed by a non-commutative phase drift operator acting on adjacent E8 root vector pairs: Δp(n) = ⌊φ⁻ⁿ · ||Rᵢ × Rⱼ||₈⌋, where the cross product magnitude in 8D space yields integer-quantized...

Rethinking approaches to Somali Studies: a narrative review of anthropological, Marxist, revisionist, and comprehensive perspectives

Somali Studies has developed over more than a century into a multidisciplinary field encompassing history, anthropology, sociology, political science, linguistics, religious studies, transnational studies and diaspora studies. Despite this breadth, the field has been shaped dispr...

Persuasive strategies and ideological framing in Cyril Ramaphosa’s 2026 State of the Nation Address: a critical discourse analysis

This study examines persuasive strategies and ideological framing in the 2026 State of the Nation Address (SONA) delivered by President Cyril Ramaphosa. The study adopted a descriptive qualitative research design and was grounded in Teun A. van Dijk’s socio-cognitive and ideologi...