Research works

Bioeconomy: from a national project to industrial development

National projects, which have been developed since 2018, are recognized as the most important key areas of socio economic development of our country. Project management, which underpins the idea of national projects, and its advantages are examined. Targeted financing of developm...

Extrachromosomal DNA: A New Therapeutic Frontier for Overcoming Cancer Drug Resistance

Extrachromosomal DNAs (ecDNAs) are acentric circular DNA molecules that frequently harbor amplified oncogenes and their regulatory elements. Although ecDNAs occur at low levels in normal cells, oncogenic ecDNAs are enriched in cancer, where they promote tumor evolution, intratumo...

Nanoamphizymes: Self‐Assembled Amphiphilic Enzymatic Nanomaterials for High‐Performance Biocatalysis and Biosensing

ABSTRACT Nanomaterials offer versatile platforms for biocatalysis by modulating enzyme stability and activity at the nano–bio interface. However, strong interfacial interactions often disrupt enzyme structure and cause substantial activity loss, while the largely empirical nature...

Entanglement, Entropy and Negentropy - Metabolism of Life

The third law of thermodynamics places absolute zero at the bottom of the temperature scale, but this floor is not where entanglement fails: it is where entanglement is maximal. We argue that what temperature destroys is the purity of the state rather than quantum correlation its...

Fluorination‐Driven Molecular Polarization Engineering in Hydroxyfluorooxoborates for Generating Strong Short‐Wavelength Nonlinear Optical Responses

ABSTRACT The short‐wavelength ultraviolet (UV, <280 nm) all‐solid‐state lasers, which rely on nonlinear optical (NLO) crystals for second‐harmonic generation (SHG), are of great significance for advanced scientific and industrial. However, the inherent randomness of obtaining non...

Techno-Economic Assessment of Membrane Distillation for Green Hydrogen Production in Australia

As global momentum builds toward decarbonisation, green hydrogen has emerged as a key pillar in Australia’s transition to a net-zero emissions future. However, the freshwater demands of large-scale electrolysis poses a significant social hurdle, particularly in a nation facing ac...

Ocean circulation changes rather than global warming drove temperature trends across the Miocene Climatic Optimum

Early-to-Middle Miocene [23 to 13.8 million years ago (Ma)] climates were ∼6° to 9°C warmer than today. Around 16.9 Ma, benthic foraminiferal oxygen isotope (δ 18 O) records suggest pronounced warming, known as the Miocene Climatic Optimum (MCO) onset. However, explaining this pu...

Designing a hybrid surgical ICU to avoid intrahospital transport in selected critically Ill patients: the CUHK-SZ institutional concept

Intrahospital transport for surgery exposes critically ill patients to equipment failure, displacement of tubes and lines, interrupted monitoring, and physiologic instability. Although transport protocols can reduce these hazards, they do not address the underlying physical decou...

Synthesis and Preliminary Biological Evaluation of a Structurally Modified Niraparib-Based PARP-Targeted PET Tracer for Tumor Imaging

Abstract Poly(ADP-ribose) polymerase (PARP) is highly expressed in various malignancies and represents an important therapeutic target. Noninvasive evaluation of PARP expression is therefore of potential clinical significance for patient stratification. In this study, we develope...

The Impact of 360-Degree Video on Social Media Word of Mouth Intention in Luxury Hospitality: The Roles of Telepresence and Experience

This study examines how 360-degree (vs. traditional) videos influence social media word-of-mouth (WOM) intention in the luxury hospitality sector. Across four studies, results show that 360-degree videos outperform traditional formats, with telepresence and luxury experience expl...

Molecular basis of phosphatidylinositol 4-kinase alpha (PI4KA) regulation by regulatory protein partners and post-translational modifications

Type III phosphatidylinositol 4-kinase alpha (PI4KA) is a lipid kinase that generates the primary pool of phosphatidylinositol 4-phosphate (PI4P) at the plasma membrane (PM). It is a master regulator of PM asymmetry and identity and provides PI4P substrate for downstream PI(4,5)P...

Financial inclusion as a pathway to sustainability goals for marginalized communities in India

India has made remarkable strides over the past two decades in expanding financial access through digital payment systems, mobile banking, and ambitious government programs. Yet this journey toward universal financial inclusion reveals a sobering paradox: as we bring more people...

Spontaneous resolution of vestibular schwannoma: A singular phenomenon

Background: The natural history of vestibular schwannoma (VS) is variable, with concerns about observation management rather than hearing loss. Shrinkage is well documented, with an undetermined hearing outcome. Case Description: We report the case of a 62-year-old female followe...

Clinical, Patient Experience and Service Outcomes of a Leisure Centre–Based NHS Musculoskeletal Physiotherapy Service: A Service Evaluation

BACKGROUND: Musculoskeletal (MSK) conditions place substantial burden on individuals and healthcare systems, increasing the demand for accessible, community-based care. This service evaluation assessed an NHS MSK physiotherapy pilot delivered in a leisure centre in a socioeconomi...

Performance Characteristics and Sensitivity Analysis of an Ammonia-Diesel Dual-Fuel Engine Under Varying Ammonia Energy Ratios and Diesel Injection Parameters

Ammonia can partially replace diesel in compression ignition engines, but the relative influences of the ammonia energy ratio (AER), pilot–main injection timing advance, and injection pressure on engine performance remain insufficiently quantified. This study evaluated these infl...

Structure, Biostratigraphy, and Numerical Modelling of the Nizampur Basin (Pakistan): Implications for Deformation in the Himalayan Fold‐Thrust Belt

ABSTRACT The Nizampur Basin in northern Pakistan preserves a structurally important segment of the Himalayan fold‐thrust belt between the Attock‐Cherat Range (ACR) and the Kalachitta Range. Its architecture records interaction among the Hissartang Fault, the Main Boundary Thrust...

Performance Evaluation of Electrostatic Particle Ionization and Electro-Nanospray for Inlet Air Treatment in Livestock Facilities Under Controlled Conditions

Disease outbreaks impose substantial economic impacts on livestock production systems due to mortality, mandatory depopulation, reduced productivity, and additional costs associated with disease mitigation and biosecurity strategies. The introduction of viruses into commercial li...

An analysis of emergency department visits for injuries among students at a large U.S. public university

Abstract Background Injuries are a significant source of morbidity and mortality among college students.While previous studies identified the most common causes of injuries among college students globally, none have examined electronic health record narratives through a qualitati...

Protein‐Polymer Dynamic Hydrogels Utilizing Native Ligand Binding for Injectable Therapeutic Delivery and 3D Printing

Dynamic hydrogels comprising networks formed from reversible interactions have shown utility in minimally invasive delivery of encapsulated therapeutics, as well as in extrusion-based 3D printing of tissue-mimetic structures. Here, we report dynamic nanocolloidal hydrogels formed...

Optimized scandium doping in Al₂Mo₃O₁₂ with NP co-doped carbon coating for enhanced low-temperature lithium storage

The development of low-temperature anode materials is crucial for the practical application of lithium-ion batteries (LIBs). Al 2− x Sc x Mo 3 O 12 ( x = 0, 0.5, 1, 1.5) materials were synthesized using a high-temperature solid-state method, and the effects of scandium doping on...