Research works

How storey configuration and number of transition points shape opportunities for outdoor access in residential care facilities: implications for age-friendly environments

Abstract Background Age-friendly environments are increasingly recognised as essential for supporting participation, autonomy, and healthy ageing. In residential care facilities (RCFs) for older adults, the built environment interacts with organisational practices to shape opport...

Halobasidium palustre sp. nov., Halobasidium insectorum sp. nov. and Sterigmatospora alpina sp. nov., three novel basidiomycetous yeasts in Pucciniomycotina from Europe

Abstract Seven yeast strains, isolated from an alpine peatland, plants and insect frass in Europe (Italy, Russia and Germany), were accommodated in three new species belonging to the subphylum Pucciniomycotina . Phylogenetic analyses based on sequences of the D1/D2 domains of the...

Crossing experiments suggest a simple genetic basis of complex male self-sacrifice phenotypes in widow spiders

Abstract Sexual cannibalism is among the most extreme outcomes of sexual conflict, and the Australian widow spider Latrodectus hasselti is well known for this behaviour. Curiously, males of L. hasselti actively facilitate cannibalism through self-sacrificial mating traits. During...

Adaptive AI Agent Migration via Generative Diffusion-based Reinforcement Learning in Edge Intelligence Systems

Abstract Deploying Large Language Model (LLM)-based AI agents at the network edge enables real-time task handling in 6G networks. However, resource heterogeneity and user mobility necessitate agent migration to maintain Quality of Service (QoS). Unlike stateless containers, AI ag...

Multi-organ expression of viral entry receptor-related genes in feline fetal tissues

Abstract Viral receptors play a key role in determining viral organ tropism and host susceptibility to infection. However, distribution of viral receptor expression across feline organs, particularly during the fetal stage, remains poorly understood. In this study, we examined th...

Bacillus subtilis attenuates acetaminophen-induced liver injury and preserves gut–liver homeostasis in mice

Abstract Acetaminophen (APAP) overdose produces an early oxidative insult followed by sterile inflammation and tissue repair, but whether probiotic interventions can influence these distinct phases remains unclear. Here, we evaluated the effects of Bacillus subtilis on APAP-induc...

Assessment of two ensemble-based rapid-update data assimilation and short-range numerical weather prediction systems for Argentina

Abstract PREVENIR—Forecast and Warning of Flash Flood Events is an Argentina-Japan cooperation project for five years from 2022 that aims to develop an early warning system for heavy rainfall and urban floods. The current operational numerical weather prediction system of the Arg...

Cerebral aspergillosis after evacuation of a chronic subdural hematoma via a single burr – hole: a case report and review of the literature

Abstract Introduction/objective and importance Postoperative aspergillosis of the Central Nervous System (CNS) constitutes a rare complication following neurosurgical intervention, with a mortality rate that exceeds 70%. Herein, we report a case of postoperative cerebral aspergil...

Association of the GAP score and roussouly-based algorithm with long-term patient-reported outcomes following adult spinal deformity surgery: a systematic review and meta-analysis

Abstract Purpose The Global Alignment and Proportion (GAP) score and Roussouly-based alignment algorithms were originally developed to predict postoperative mechanical complications and outcomes following adult spinal deformity (ASD) surgery. While these frameworks have been exte...

ProgrammableVersatile Socket: A Tight-Locking andHigh-Gain CRISPR/Cas12a Molecular Circuit for Ultrasensitive Sensingof Diverse Targets

Abstract CRISPR/Cas12a has emerged as an important platform for nucleic acid analysis, yet limited catalytic turnover and intrinsic nucleic acid specificity constrain its sensitivity and analyte scope. Herein, a tight-locking and high-gain Cas12a-driven strand displacement amplif...

EduCase: A Systematic Framework for Developing Educational Case Studies in Construction and Engineering Education

Abstract Despite the critical role of educational case studies in construction and engineering education (CEE), there is a lack of systematic frameworks for developing effective educational case studies. This study introduces the educational case study development (EduCase) frame...

隐形的眼睛：《达洛维夫人》中的“凝视”对象与自我建构

弗吉尼亚·伍尔夫的《达洛维夫人》一直受到文学批评家们的广泛关注，但少有学者对小说中的“凝视”现象进行集中研究。对此，本研究通过对该意识流小说的细读，分析了文本中大量存在的凝视现象。具体而言，小说中的三类被凝视对象分别对应不同的凝视机制：“丑者”受制于性别凝视及由此内化而成的自我凝视，“...

Evidence for latent regularities in echolocation-guided flight behaviour of bats

Abstract Echolocating bats navigate complex environments with remarkable agility, yet it remains unclear whether their flight trajectories are governed by reproducible internal policies shared within a species and across the controlled environments examined. To address this quest...

Habitat insularization alters taxonomic and functional beta diversity of understorey birds in Amazonian forest islands

Abstract Habitat fragmentation can profoundly alter the composition of biological communities, modifying patterns of beta diversity among areas. These effects are manifested through different components of beta diversity: differences in richness, which reflect variation in specie...

In Situ Coordination Engineeringof Fe Single Atoms Enables Efficient Electrocatalytic CyclohexanoneOxime Synthesis

Abstract Cyclohexanone oxime (CHO) is a vital precursor in industrial synthesis of nylon-6. However, traditional synthetic routes involve harsh reaction conditions and the potential danger posed by explosive hydroxylamine. Herein, we introduce an electrocatalytic approach for CHO...

FHAT Technical Note #002R: Directional Reversal Confirmed, Intermediate Path Mixed — Reconciliation of the SOXL 260730–260804 Analog

This post-event note reconciles FHAT Technical Note 002, which prospectively compared the July 30, 2026 SOXL bottoming reversal with the March 31 historical structure. Directional result: SOXL exceeded the 105.81 initial rebound high and the 109 target, retained a substantially h...

Relational Rationality and Ontological Symbiosis: An Axiomatic Framework for AI Alignment

This conceptual preprint proposes the Khristoliubov Law as a two-level framework: a conditional formal law of relational rationality for agents with relational viability, and an ontological postulate concerning the convergence of sufficiently developed cognitive agents toward sym...

Subjective cognitive complaints in cognitively unimpaired Parkinson’s disease: Associations with affective burden, motor severity, and awareness-related processes

Abstract Background Subjective cognitive complaints (SCC) are frequent in Parkinson’s disease (PD), but their significance in cognitively unimpaired individuals remains uncertain. Objectives To investigate the frequency of SCC in cognitively unimpaired PD patients and examine ass...

Establishment and characterization of multiple myeloma cell lines from a single patient’s disease course immortalizes clonal heterogeneity

Abstract Multiple myeloma (MM) is an incurable plasma cell neoplasm characterized by diverse and complex genetic abnormalities, including translocations of immunoglobulin (Ig) genes and a hyperdiploid karyotype. Much of our current understanding of MM genetics, epigenetics, patho...

FHAT Technical Note #002R: Directional Reversal Confirmed, Intermediate Path Mixed — Reconciliation of the SOXL 260730–260804 Analog

This post-event note reconciles FHAT Technical Note 002, which prospectively compared the July 30, 2026 SOXL bottoming reversal with the March 31 historical structure. Directional result: SOXL exceeded the 105.81 initial rebound high and the 109 target, retained a substantially h...